Spbetavirus

VIRION

Non-enveloped, head-tail structure. The head is about 81 nm in diameter. The tail is relatively rigid, about 355 nm in length and 10 nm in width and possesses 6 club-shaped terminal fibers. There is no collar.

GENOME

Linear, dsDNA genome of about 134 kb, containing about 187 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Viral exolysin degrades host cell wall locally.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA.
  6. Transcription and translation of late genes
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fiber assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.