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DNA-directed RNA polymerase (kw:KW-0240)

Virally encoded protein (EC 2.7.7.6) which synthesizes RNA using DNA as a template. This enzyme activity might be necessary for the viral genome transcription of some viruses.

Links Uniprot Keyword: KW-0240

GO ontology: GO:0000428
Virus All these viruses have been shown to encode a viral DNA-directed RNA polymerase:



Ascoviridae

Asfarviridae

Baculoviridae

Possibly Myoviridae

Phycodnaviridae

Podoviridae

Poxviridae

Possibly Siphoviridae

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

133 entries grouped by protein

1 entry

Probable DNA-directed RNA polymerase subunit 343L (EC 2.7.7.6)

343L_IIV6
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) reference strain

1 entry

Putative DNA-directed RNA polymerase subunit 454R

454R_IIV6
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) reference strain

1 entry

DNA helicase/primase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)

HELIC_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Probable DNA-directed RNA polymerase catalytic subunit (EC 2.7.7.6) (Late expression factor 8)

LEF8_NPVAC
Autographa californica nuclear polyhedrosis virus (AcMNPV) reference strain

1 entry

Putative P4-specific DNA primase (EC 2.7.7.-) (EC 3.6.4.12)

PRIM_BPP4
Enterobacteria phage P4 (Bacteriophage P4) reference strain

pdb 1KA8

12 entries

DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

Select_allDeselect_all
RP07_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP07_MCV1
Molluscum contagiosum virus subtype 1 (MOCV) (MCVI) reference strain
RP07_MONPV
Monkeypox virus reference strain
RP07_MYXVL
Myxoma virus (strain Lausanne) (MYXV) reference strain
RP07_RFVKA
Rabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza)) reference strain
RP07_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 8C8H

RP07_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP07_VACCA
Vaccinia virus (strain Ankara) (VACV)

pdb 6RIE

RP07_VACCC
Vaccinia virus (strain Copenhagen) (VACV)

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP07_VACCT
Vaccinia virus (strain Tian Tan) (VACV)
RP07_VARV
Variola virus
RP07_YLDV
Yaba-like disease virus (YLDV)

15 entries

DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

Select_allDeselect_all
RP132_CAMPS
Camelpox virus (strain CMS) reference strain
RP132_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP132_MONPV
Monkeypox virus reference strain

DNA-directed RNA polymerase (EC 2.7.7.6)

RP132_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP132_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

pdb 6RIE; 8C8H

RP132_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain

DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

RP132_CAMPM
Camelpox virus (strain M-96)
RP132_CWPXB
Cowpox virus (strain Brighton Red) (CPV)
RP132_CWPXG
Cowpox virus (strain GRI-90 / Grishak) (CPV)
RP132_ECTVM
Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)
RP132_MONPZ
Monkeypox virus (strain Zaire-96-I-16) (MPX)
RP132_RABPU
Rabbitpox virus (strain Utrecht) (RPV)
RP132_VACCA
Vaccinia virus (strain Ankara) (VACV)

DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

RP132_VACCT
Vaccinia virus (strain Tian Tan) (VACV)

DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

RP132_VARV
Variola virus

DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

7 entries

DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)

Select_allDeselect_all
RP147_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP147_MONPV
Monkeypox virus reference strain
RP147_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP147_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 8C8H

RP147_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP147_VACCA
Vaccinia virus (strain Ankara) (VACV)

pdb 6RIE

RP147_VARV
Variola virus

7 entries

DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)

Select_allDeselect_all
RP18_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP18_MONPV
Monkeypox virus reference strain
RP18_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP18_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 8C8H

RP18_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP18_VACCA
Vaccinia virus (strain Ankara) (VACV)

pdb 6RIE

RP18_VARV
Variola virus

6 entries

DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)

Select_allDeselect_all
RP19_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP19_MONPV
Monkeypox virus reference strain
RP19_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP19_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 8C8H

RP19_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP19_VACCA
Vaccinia virus (strain Ankara) (VACV)

pdb 6RIE

7 entries

DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)

Select_allDeselect_all
RP22_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP22_MONPV
Monkeypox virus reference strain
RP22_MYXVL
Myxoma virus (strain Lausanne) (MYXV) reference strain

DNA-directed RNA polymerase 21 kDa subunit (EC 2.7.7.6)

RP22_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP22_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 6RIE; 8C8H

RP22_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP22_MYXVU
Myxoma virus (strain Uriarra) (MYXV)

DNA-directed RNA polymerase 21 kDa subunit (EC 2.7.7.6)

5 entries

DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)

Select_allDeselect_all
RP30_MONPV
Monkeypox virus reference strain
RP30_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP30_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 8C8H

RP30_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP30_VACCA
Vaccinia virus (strain Ankara) (VACV)

pdb 6RIE

8 entries

DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)

Select_allDeselect_all
RP35_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RP35_MONPV
Monkeypox virus reference strain
RP35_VACCC
Vaccinia virus (strain Copenhagen) (VACV) reference strain

pdb 8P0J; 8P0K; 8P0N; 8RQK

RP35_VACCW
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

pdb 8C8H

RP35_VAR67
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain
RP35_RABPU
Rabbitpox virus (strain Utrecht) (RPV)
RP35_VACCA
Vaccinia virus (strain Ankara) (VACV)

pdb 6RIE

RP35_VACCT
Vaccinia virus (strain Tian Tan) (VACV)

8 entries

DNA-directed RNA polymerase RPB1 homolog (RPB1 homolog) (EC 2.7.7.6)

Select_allDeselect_all
RPB1_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQX; 8YQY; 8YQZ

RPB1_FRG3G
Frog virus 3 (isolate Goorha) (FV-3) reference strain

Putative DNA-directed RNA polymerase 008R (EC 2.7.7.6)

RPB1_IIV3
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) reference strain

Probable DNA-directed RNA polymerase II subunit RPB1 homolog (EC 2.7.7.6)

RPB1_IIV6
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) reference strain

Probable DNA-directed RNA polymerase II subunit RPB1 homolog (EC 2.7.7.6)

RPB1_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)

DNA-directed RNA polymerase RPB1 homolog (EC 2.7.7.6)

RPB1_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB1_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB1_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

5 entries

DNA-directed RNA polymerase RPB10 homolog (RPB10 homolog)

Select_allDeselect_all
RPB10_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQY; 8YQZ

RPB10_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)
RPB10_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB10_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB10_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

8 entries

DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6)

Select_allDeselect_all
RPB2_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQY; 8YQZ

RPB2_FRG3G
Frog virus 3 (isolate Goorha) (FV-3) reference strain

Putative DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)

RPB2_IIV3
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) reference strain

Probable DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)

RPB2_IIV6
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) reference strain

Probable DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)

RPB2_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)
RPB2_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB2_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB2_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

5 entries

DNA-directed RNA polymerase RPB3-11 homolog (RPB3-11 homolog)

Select_allDeselect_all
RPB3_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQY; 8YQZ

RPB3_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)
RPB3_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB3_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB3_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

5 entries

DNA-directed RNA polymerase RPB5 homolog (RPB5 homolog)

Select_allDeselect_all
RPB5_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQY; 8YQZ

RPB5_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)
RPB5_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB5_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB5_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

5 entries

DNA-directed RNA polymerase RPB6 homolog (RPB6 homolog)

Select_allDeselect_all
RPB6_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQY; 8YQZ

RPB6_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)

DNA-directed RNA polymerase subunit 6 homolog (RPB6 homolog)

RPB6_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB6_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB6_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

DNA-directed RNA polymerase subunit 6 homolog (RPB6 homolog)

5 entries

DNA-directed RNA polymerase RPB7 homolog (RPB7 homolog)

Select_allDeselect_all
RPB7_ASFB7
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

pdb 8Q3B; 8Q3K; 8XX4; 8XX5; 8XXP; 8XXT; 8XY6; 8Y0E; 8YQT; 8YQU; 8YQV; 8YQW; 8YQX; 8YQY; 8YQZ

RPB7_ASFK5
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)
RPB7_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB7_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)
RPB7_ASFWA
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

2 entries

DNA-directed RNA polymerase RPB9 homolog (RPB9 homolog)

Select_allDeselect_all
RPB9_ASFM2
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)
RPB9_ASFP4
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)

1 entry

DNA-directed RNA polymerase subunit 1 (EC 2.7.7.6)

RPO1_MIMIV
Acanthamoeba polyphaga mimivirus (APMV) reference strain

1 entry

DNA-directed RNA polymerase subunit 2 (EC 2.7.7.6)

RPO2_MIMIV
Acanthamoeba polyphaga mimivirus (APMV) reference strain

2 entries

DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)

Select_allDeselect_all
RPO5_FOWPN
Fowlpox virus (strain NVSL) (FPV) reference strain
RPO5_MIMIV
Acanthamoeba polyphaga mimivirus (APMV) reference strain

DNA-directed RNA polymerase subunit 5 (EC 2.7.7.6)

1 entry

DNA-directed RNA polymerase subunit 6 (EC 2.7.7.6)

RPO6_MIMIV
Acanthamoeba polyphaga mimivirus (APMV) reference strain

2 entries

Probable DNA-directed RNA polymerase subunit beta (EC 2.7.7.6) (Late expression factor 8)

Select_allDeselect_all
RPOB_NPVOP
Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) reference strain
RPOB_NPVSL
Spodoptera littoralis nuclear polyhedrosis virus (SlNPV)

5 entries

DNA-directed RNA polymerase (EC 2.7.7.6)

Select_allDeselect_all
RPOL_BPKMV
Pseudomonas phage phiKMV reference strain
RPOL_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)

pdb 1ARO; 1CEZ; 1H38; 1MSW; 1QLN; 1S0V; 1S76; 1S77; 2PI4; 2PI5; 3E2E; 3E3J; 4RNP; 8DH0; 8DH1; 8DH2; 8DH3; 8DH4; 8DH5

RPOL_BPK11
Enterobacteria phage K11 (Bacteriophage K11)
RPOL_BPSP6
Enterobacteria phage SP6 (Bacteriophage SP6)
RPOL_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Virion DNA-directed RNA polymerase (vRNAP) (EC 2.7.7.6) (Gene product 50) (gp50)

RPOLV_BPN4
Enterobacteria phage N4 (Bacteriophage N4) reference strain

pdb 2PO4; 3C2P; 3C3L; 3C46; 3Q0A; 3Q22; 3Q23; 3Q24; 4FF1; 4FF2; 4FF3; 4FF4

2 entries

Late genes activator (Early protein GP4)

Select_allDeselect_all
VG4_BPB03
Bacillus phage B103 (Bacteriophage B103)
VG4_BPNF
Bacillus phage Nf (Bacteriophage Nf)

Late genes activator (Early protein GP4) (GPF)

1 entry

Putative DNA-directed RNA polymerase subunit L376 (EC 2.7.7.6)

YL376_MIMIV
Acanthamoeba polyphaga mimivirus (APMV) reference strain

1 entry

DNA-directed RNA polymerase YonO (EC 2.7.7.6) (DNA-dependent RNA polymerase YonO)

YONO_BPSPB
Bacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta) reference strain

1 entry

Putative DNA directed RNA polymerase subunit R470 (EC 2.7.7.6)

YR470_MIMIV
Acanthamoeba polyphaga mimivirus (APMV) reference strain