Virus
|
Family
|
|
virion
|
Host
|
function
|
Viral protein
|
Receptor
|
Type
|
Host expression
|
Virus tropism
|
entry mode
|
Feline leukemia virus A |
Retroviridae, gammaretrovirus |
RT |
Env |
Felidae |
Entry |
Envelope glycoprotein |
SLC19A2(Pit2) |
Transporter |
? |
Lymphocytes? |
? |
Feline leukemia virus B |
Retroviridae, gammaretrovirus |
RT |
Env |
Felidae |
Entry |
Envelope glycoprotein |
SLC20A1(Pit1), SLC20A2(Pit2) |
Transporter |
Muscle. placenta, heart, liver and kidney. |
Lymphocytes? |
Fusion with host cell membrane |
Feline leukemia virus C |
Retroviridae,gammaretrovirus |
RT |
Env |
Felidae |
Entry |
Envelope glycoprotein |
FLVCR1 |
Transporter |
Lymphocytes |
Lymphocytes? |
Fusion with host cell membrane |
Feline leukemia virus T |
Retroviridae, gammaretrovirus |
RT |
Env |
Felidae |
Entry |
Envelope glycoprotein |
FeLIX |
endogenous retrovirus surface protein |
Lymphocytes |
T-Lymphocytes? |
Fusion with host cell membrane |
Feline leukemia virus T |
Retroviridae, gammaretrovirus |
RT |
Env |
Felidae |
Entry |
Envelope glycoprotein |
SLC20A1(Pit1) |
Transporter |
Muscle. placenta, heart, liver and kidney |
T-Lymphocytes |
Fusion with host cell membrane |
Gibbon ape leukemia virus |
Retroviridae, gammaretrovirus |
RT |
Env |
Apes |
Entry |
Envelope glycoprotein |
SLC20A1(Pit1) |
Transporter |
Muscle. placenta, heart, liver and kidney |
Lymphocytes |
Fusion with host cell membrane |
Murine leukemia virus |
Retroviridae, gammaretrovirus |
RT |
Env |
Rodent |
Entry |
Envelope glycoprotein |
SLC19A2(Pit2) |
Transporter |
? |
Lymphocyte |
Fusion with host cell membrane |
Endogenous murine type C ecotropic retrovirus |
Retroviridae, gammaretrovirus |
RT |
Env |
Mouse |
Entry |
Envelope glycoprotein |
Slc7a1(CAT1) |
Transporter |
Skin, pancreas, gastrointestinal tract |
? |
Caveolin-mediated endocytosis |
Endogenous xenotropic and polytropic murine leukemia virus |
Retroviridae, gammaretrovirus |
RT |
Env |
Mouse |
Entry |
Envelope glycoprotein |
XPR1 |
Transporter |
? |
? |
Fusion with host cell membrane |
Endogenous subgroup A avian leukosis and sarcoma virus |
Retroviridae, alpharetrovirus |
RT |
Env |
Chicken |
Entry |
Envelope glycoprotein |
Tva |
Receptor |
? |
Mostly lymphocytes |
? |
Endogenous subgroup B, D and E avian leukosis and sarcoma virus |
Retroviridae, alpharetrovirus |
RT |
Env |
Chicken |
Entry |
Envelope glycoprotein |
Tvb |
Receptor |
? |
Mostly lymphocytes |
? |
Bovine leukemia virus |
Retroviridae, deltaretrovirus |
RT |
Env |
Bovine, Ovine |
Entry |
Envelope glycoprotein |
Blvr |
? |
? |
B lymphocytes |
? |
Mouse mammary tumor virus |
Retroviridae, betaretrovirus |
RT |
Env |
Mouse |
Entry |
Envelope glycoprotein |
Transferin receptor (TFRC) |
Receptor |
Monocytes, lymphocytes, erythrocytes |
primary: macrophages in Peyer s patches of the gastrointestinal tracts, secondary B and T lymphocytes |
Fusion with host cell membrane |
Spleen necrosis virus |
Retroviridae, gammaretrovirus |
RT |
Env |
Duck |
Entry |
Envelope glycoprotein |
SLC1A5 |
Transporter |
Ubiquitous |
? |
? |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Adhesion |
Envelope gp120 |
CD4 |
Receptor |
T-lymphocytes, macrophages, dendritic cells |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Adhesion |
Envelope gp120 |
DC-SIGN |
Lectin |
Dendritic cells |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Adhesion |
Envelope gp120 |
CLEC4M(L-SIGN) |
Lectin |
liver sinusoidal endothelial cells and lymph node |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Atdhesion |
Envelope gp120 |
Heparan sulfate |
Polysaccharide |
? |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Adhesion |
Envelope gp120 |
? |
Glycosphingolipid |
? |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Adhesion |
Host ICAM1 |
LFA1 |
Adhesion molecule |
Lymphocytes |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Entry |
Envelope gp120 |
CCr5 |
Receptor |
T-lymphocytes, macrophages, dendritic cells |
T-lymphocytes |
Clathrin-mediated endocytosis |
HIV-1 |
Retroviridae, lentivirus |
RT |
Env |
Human |
Entry |
Envelope gp120 |
CXCR4 |
Receptor |
Lymphocytes |
T-lymphocytes |
Clathrin-mediated endocytosis |
Simian immunodeficiency virus |
Retroviridae, lentivirus |
RT |
Env |
Apes |
Adhesion |
Envelope glycoprotein |
CD4 |
Receptor |
T-lymphocytes, macrophages, dendritic cells |
T lymphocytes |
? |
Feline immunodefficiency virus |
Retroviridae, lentivirus |
RT |
Env |
Felidae |
Adhesion |
Envelope glycoprotein |
TNFRSF4 |
Receptor |
Lymphocyte |
T4 Lymphocyte |
? |
Feline immunodefficiency virus |
Retroviridae, lentivirus |
RT |
Env |
Felidae |
? |
Envelope glycoprotein |
CXCr4 |
Receptor |
Lymphocytes |
T4 Lymphocyte |
? |
Hepatitis B virus |
Hepadnaviridae, Orthohepadnavirus |
RT |
Env |
Human |
Adhesion |
Large envelope protein |
Heparan sulfate |
Polysaccharide |
? |
Hepatocyte |
Caveolin-mediated endocytosis |
Hepatitis B virus |
Hepadnaviridae, Orthohepadnavirus |
RT |
Env |
Human |
Adhesion |
Large envelope protein |
SLC10A1(NTCP) |
Transporter |
hepatocyte |
Hepatocyte |
Caveolin-mediated endocytosis |
Hepatitis B virus |
Hepadnaviridae, Orthohepadnavirus |
RT |
Env |
Human |
Adhesion |
Large envelope protein |
Mannose receptor(MRC1) |
Receptor |
Macrophages, dendritic cells, dermal fibroblasts and keratinocytes |
Hepatocyte |
Caveolin-mediated endocytosis |
Avian hepatitis B virus |
Hepadnaviridae, Avihepadnavirus |
RT |
Env |
Birds |
Entry |
Large envelope protein |
Carboxypeptidase D |
Peptidase |
? |
hepatocyte |
Caveolin-mediated endocytosis |
Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility
Gary Chan, Maciej T. Nogalski, Andrew D. Yurochko
Proc. Natl. Acad. Sci. U.S.A. December 29, 2009; 106: 22369?22374
Influenza entry pathways in polarized MDCK cells
Yueting Zhang, Gary R. Whittaker
Biochem. Biophys. Res. Commun. July 18, 2014; 450: 234?239
Fusion of Sendai virus and individual host cells and inhibition of fusion by lipophosphoglycan measured with image correlation spectroscopy
B. J. Rasmusson, T. D. Flanagan, S. J. Turco, R. M. Epand, N. O. Petersen
Biochim. Biophys. Acta September 16, 1998; 1404: 338?352
Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2
Teresa R. Johnson, Jason S. McLellan, Barney S. Graham
J. Virol. February 2012; 86: 1339?1347
The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus
Wy Ching Ng, Sarah L. Londrigan, Najla Nasr, Anthony L. Cunningham, Stuart Turville, Andrew G. Brooks, Patrick C. Reading
J. Virol. 2015; 90: 206?221
A Sialylated Voltage-Dependent Ca(2+) Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells.
Fujioka Y, Nishide S, Ose T, Suzuki T, Kato I, Fukuhara H, Fujioka M, Horiuchi
K, Satoh AO, Nepal P, Kashiwagi S, Wang J, Horiguchi M, Sato Y, Paudel S, Nanbo
A, Miyazaki T, Hasegawa H, Maenaka K, Ohba Y.
Cell Host Microbe. 2018 Jun 13;23(6):809-818
A putative thiamine transport protein is a receptor for feline leukemia virus subgroup A
Ramon Mendoza, Maria M Anderson, Julie Overbaugh
J. Virol. April 2006; 80: 3378?3385
Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus
Y Takeuchi, R G Vile, G Simpson, B O?Hara, M K Collins, R A Weiss
J. Virol. February 1992; 66: 1219?1222
Cloning of the cellular receptor for feline leukemia virus subgroup C (FeLV-C), a retrovirus that induces red cell aplasia
J G Quigley, C C Burns, M M Anderson, E D Lynch, K M Sabo, J Overbaugh, J L Abkowitz
Blood February 1, 2000; 95: 1093?1099
Feline leukemia virus T entry is dependent on both expression levels and specific interactions between cofactor and receptor
Heather H Cheng, Maria M Anderson, Julie Overbaugh
Virology March 1, 2007; 359: 170?178
Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus
B O?Hara, S V Johann, H P Klinger, D G Blair, H Rubinson, K J Dunn, P Sass, S M Vitek, T Robins
Cell Growth Differ. March 1990; 1: 119?127
Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus
D G Miller, R H Edwards, A D Miller
Proc. Natl. Acad. Sci. U.S.A. January 4, 1994; 91: 78?82
Identification of a cellular cofactor required for infection by feline leukemia virus
M M Anderson, A S Lauring, C C Burns, J Overbaugh
Science March 10, 2000; 287: 1828?1830
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
L M Albritton, L Tseng, D Scadden, J M Cunningham
Cell May 19, 1989; 57: 659?666
A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: possible role in G protein-coupled signal transduction
J L Battini, J E Rasko, A D Miller
Proc. Natl. Acad. Sci. U.S.A. February 16, 1999; 96: 1385?1390
A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor
P Bates, J A Young, H E Varmus
Cell September 24, 1993; 74: 1043?1051
Identification and characterization of a shared TNFR-related receptor for subgroup B, D, and E avian leukosis viruses reveal cysteine residues required specifically for subgroup E viral entry
H B Adkins, J Brojatsch, J A Young
J. Virol. April 2000; 74: 3572?3578
Isolation of the missing 5?-end of the encoding region of the bovine leukemia virus cell receptor gene
J Ban, A T Truong, B Horion, C Altaner, A Burny, D Portetelle, R Kettmann
Arch. Virol. 1994; 138: 379?383
Mouse mammary tumor virus uses mouse but not human transferrin receptor 1 to reach a low pH compartment and infect cells
Enxiu Wang, Nyamekye Obeng-Adjei, Qihua Ying, Laurent Meertens, Tanya Dragic, Robert A Davey, Susan R Ross
Virology November 25, 2008; 381: 230?240
The RD114/simian type D retrovirus receptor is a neutral amino acid transporter
J E Rasko, J L Battini, R J Gottschalk, I Mazo, A D Miller
Proc. Natl. Acad. Sci. U.S.A. March 2, 1999; 96: 2129?2134
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
P J Maddon, A G Dalgleish, J S McDougal, P R Clapham, R A Weiss, R Axel
Cell November 7, 1986; 47: 333?348
The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site
Elodie Crublet, Jean-Pierre Andrieu, Romain R Viv?s, Hugues Lortat-Jacob
J. Biol. Chem. May 30, 2008; 283: 15193?15200
HIV: cell binding and entry
Craig B Wilen, John C Tilton, Robert W Doms
Cold Spring Harb Perspect Med 2012; 2
Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1
A Alfsen, P Iniguez, E Bouguyon, M Bomsel
J. Immunol. May 15, 2001; 166: 6257?6265
The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule
Q J Sattentau, P R Clapham, R A Weiss, P C Beverley, L Montagnier, M F Alhalabi, J C Gluckmann, D Klatzmann
AIDS April 1988; 2: 101?105
Use of CD134 as a primary receptor by the feline immunodeficiency virus
Masayuki Shimojima, Takayuki Miyazawa, Yasuhiro Ikeda, Elizabeth L McMonagle, Hayley Haining, Hiroomi Akashi, Yasuhiro Takeuchi, Margaret J Hosie, Brian J Willett
Science February 20, 2004; 303: 1192?1195
Shared usage of the chemokine receptor CXCR4 by primary and laboratory-adapted strains of feline immunodeficiency virus
J Richardson, G Pancino, R Merat, T Leste-Lasserre, A Moraillon, J Schneider-Mergener, M Alizon, P Sonigo, N Heveker
J. Virol. May 1999; 73: 3661?3671
Role of DC-SIGN and L-SIGN receptors in HIV-1 vertical transmission
Ronaldo Celerino da Silva, Ludovica Segat, Sergio Crovella
Hum. Immunol. April 2011; 72: 305?311