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G1/S host cell cycle checkpoint dysregulation by virus (kw:KW-1078)

Upon infection, viruses alter the environment of infected cells in order to replicate more efficiently. Modulation of host cell cycle progression is commonly used to maximize viral replication. Among the key steps, transition from the G1 to S phase is deregulated by many viral proteins. Members of the retinoblastoma (Rb) family of tumors repressors are transcriptional regulators that critically regulate the G1 phase.

Many viruses deregulate G1/S transition of the host cell cycle either to inhibit or to activate the transition.

Viral molecular biology Virion
Virus entry
Virus latency
Transcription and replication
Host-virus interactions
Virus exit
Modulation of host cell cycle Host G2/M cell cycle arrest by virus
G1/S host cell cycle checkpoint dysregulation by virus
G0/G1 host cell cycle checkpoint dysregulation by virus
Modulation of host cell cycle by viral cyclin-like protein
Inhibition of host mitotic exit by virus
Links Uniprot Keyword:
GO ontology: GO:0039645
Virus -Mouse cytomegalovirus
(Herpesviridae , Muromegalovirus)
-Herpes simplex virus
(Herpesviridae , Simplexvirus)
-Human cytomegalovirus (HHV-5)
(Herpesviridae , Cytomegalovirus)
-Epstein-barr virus
(Herpesviridae , Lymphocryptovirus)
-Adenovirus
(Adenoviridae , Mastadenovirus)
-HPV
(Papillomaviridae , alphapillomaviridae)
-SV40
(Polyomaviridae , Polyomavirus)
-HCV (Flaviviridae , Hepacivirus)
-HTLV-1 (Retroviridae , Deltaretrovirus)
-Bean yellow dwarf virus (Geminiviridae , Mastrevirus)
-SARS-CoV (Coronaviridae , Betacoronavirus)

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

201 entries grouped by strain

4 entries

Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) reference strain

Select_allDeselect_all
EAD_EBVB9 DNA polymerase processivity factor BMRF1 (Early Antigen Diffused) (EA-D) (Polymerase accessory ...

pdb 2Z0L

BZLF1_EBVB9 Lytic switch protein BZLF1 (EB1) (Protein Z) (Trans-activator protein BZLF1) (Zta) (bZIP ...

pdb 1ZSD; 2AK4; 2AXF; 2AXG; 2C9L; 2C9N; 2NX5; 3KWW; 3KXF; 3SPV; 3VFN; 3VFO; 3VFP; 3VFR; 5SZX; 7NX5

EBNA6_EBVB9 Epstein-Barr nuclear antigen 6 (EBNA-6) (EBV nuclear antigen 6) (Epstein-Barr nuclear antigen 3C) ...

pdb 1CG9; 2BSR; 3DX6; 3DX7; 3DX8; 3DXA

CEP2_EBVB9 Cytoplasmic envelopment protein 2 (Tegument protein BGLF2)

4 entries

Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) reference strain

Select_allDeselect_all
PP71_HCMVA Protein pp71 (pp71) (71 kDa upper matrix phosphoprotein) (Phosphoprotein UL82) (ppUL82) (Tegument ...

pdb 8QDO

VIE2_HCMVA Viral transcription factor IE2 (IE2) (Protein UL122)

pdb 6K5R; 6K5T

VIE1_HCMVA Immediate early protein IE1 (IE1) (55 kDa immediate-early protein 1) (IE1p72) (IE72)

pdb 6TGZ

ICP27_HCMVA mRNA export factor ICP27 homolog

4 entries

Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5) reference strain

Select_allDeselect_all
PP71_HCMVM Protein pp71
VIE1_HCMVM Immediate early protein IE1 (IE1) (55 kDa immediate-early protein 1) (IE1p72) (IE72)
VIE2_HCMVM Viral transcription factor IE2 (IE2) (Protein UL122)
ICP27_HCMVM mRNA export factor ICP27 homolog

3 entries

Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4) reference strain

Select_allDeselect_all
EAD_EBVA8 DNA polymerase processivity factor BMRF1 (Early Antigen Diffused) (EA-D) (Polymerase accessory ...
CEP2_EBVA8 Cytoplasmic envelopment protein 2 (Tegument protein BGLF2)
EBNA6_EBVA8 Epstein-Barr nuclear antigen 6 (EBNA-6) (EBV nuclear antigen 6) (Epstein-Barr nuclear antigen 3C) ...

2 entries

Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2) reference strain

Select_allDeselect_all
REP68_AAV2S Protein Rep68 (EC 3.6.4.12)

pdb 1S9H; 1U0J; 4ZO0; 4ZQ9; 5DCX; 6XB8; 7JSE; 7JSF; 7JSG; 7JSH; 7JSI; 9BC5; 9BU7

REP78_AAV2S Protein Rep78

pdb 5BYG

1 entry

B-lymphotropic polyomavirus (LPV) reference strain

LT_POVLY Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Bean yellow dwarf virus (BeYDV) reference strain

REPA_BEYDV Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Bovine papillomavirus type 1 reference strain

VE7_BPV1 Protein E7

1 entry

Bovine papillomavirus type 3 reference strain

VE7_BPV3 Protein E7

1 entry

Bovine papillomavirus type 5 reference strain

VE7_BPV5 Protein E7

1 entry

Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1) reference strain

LT_POVBO Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1) reference strain

LT_BFPYV Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Canine adenovirus serotype 2 (strain Toronto A 26-61) (CAdV-2) (Canine adenovirus 2 (strain Toronto A 26-61)) reference strain

E1A_ADECT Early E1A protein (Early E1A 25 kDa protein)

1 entry

Canine oral papillomavirus (strain Y62) (COPV) reference strain

VE7_COPV6 Protein E7

1 entry

Chloris striate mosaic virus (CSMV) reference strain

REPA_CSMV Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Cottontail rabbit papillomavirus (strain Kansas) (CRPV) (Papillomavirus sylvilagi) reference strain

VE7_CRPVK Protein E7

1 entry

European elk papillomavirus (EEPV) reference strain

VE7_PAPVE Protein E7

1 entry

Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain

MEQ_GAHVM Oncoprotein MEQ (MEQ)

1 entry

Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1) reference strain

LT_POVHA Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Hepatitis C virus genotype 1a (isolate H77) (HCV) reference strain

POLG_HCV77 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1A1R; 1A1V; 1CWX; 1HEI; 1JR6; 1N1L; 1ONB; 1R7C; 1R7D; 1R7E; 1R7F; 1R7G; 1RGQ; 2A4R; 2F9V; 2HD0; 2JXF; 2KDR; 2N1P; 2O8M; 2OBO; 2OBQ; 2OC0; 2OC1; 2OC7; 2OC8; 2OIN; 2P59; 2QV1; 2XI2; 2XI3; 2XNI; 3RC4; 3RC5; 4CL1; 4JZN; 4JZO; 4MWF; 4N0Y; 4Q0X; 4XVJ; 4Z0X; 5EOC; 5ERW; 5FGB; 5FGC; 5JZI; 5YXN; 5YXU; 6BQJ; 6BQK; 6BZU; 6BZV; 6BZW; 6BZY; 6UYD; 6WO5; 6WOQ; 7DUU

1 entry

Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) reference strain

TAX_HTL1C Protein Tax-1 (Protein X-LOR) (Protein PX) (Trans-activating transcriptional regulatory protein of ...

pdb 1AO7; 1BD2; 1HHK; 1IM3; 2AV1; 2AV7; 5IRO; 6UZ1; 7QRS; 7QRT; 7QS8

1 entry

Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) reference strain

TAX_HTL1A Protein Tax-1 (Protein X-LOR) (Protein PX) (Trans-activating transcriptional regulatory protein of ...

pdb 7P73; 7PC3; 7PC4; 7PC9

1 entry

Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12) reference strain

E1A_ADE12 Early E1A protein (Early E1A 29.5 kDa protein)

1 entry

Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2) reference strain

E1A_ADE02 Early E1A protein (Early E1A 32 kDa protein)

1 entry

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) reference strain

E1A_ADE05 Early E1A protein (Early E1A 32 kDa protein)

pdb 2KJE; 2R7G; 6H6D; 6H6H

1 entry

Human adenovirus F serotype 40 (HAdV-40) (Human adenovirus 40) reference strain

E1A_ADE40 Early E1A protein (Early E1A 27 kDa protein)

1 entry

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain

ICP27_HHV11 mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)

pdb 2KT5; 4YXP; 5BQK

1 entry

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain

ICP27_HHV2H mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)

1 entry

Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus) reference strain

KBZIP_HHV8P E3 SUMO-protein ligase K-bZIP (EC 2.3.2.-) (E3 SUMO-protein transferase K-bZIP)

1 entry

Human papillomavirus 11 reference strain

VE7_HPV11 Protein E7

1 entry

Human papillomavirus 15 reference strain

VE7_HPV15 Protein E7

1 entry

Human papillomavirus 21 reference strain

VE7_HPV21 Protein E7

1 entry

Human papillomavirus 22 reference strain

VE7_HPV22 Protein E7

1 entry

Human papillomavirus 23 reference strain

VE7_HPV23 Protein E7

1 entry

Human papillomavirus 24 reference strain

VE7_HPV24 Protein E7

1 entry

Human papillomavirus 27 reference strain

VE7_HPV27 Protein E7

1 entry

Human papillomavirus 29 reference strain

VE7_HPV29 Protein E7

1 entry

Human papillomavirus 30 reference strain

VE7_HPV30 Protein E7

1 entry

Human papillomavirus 31 reference strain

VE7_HPV31 Protein E7

1 entry

Human papillomavirus 35 reference strain

VE7_HPV35 Protein E7

1 entry

Human papillomavirus 39 reference strain

VE7_HPV39 Protein E7

1 entry

Human papillomavirus 4 reference strain

VE7_HPV04 Protein E7

1 entry

Human papillomavirus 44 reference strain

VE7_HPV44 Protein E7

1 entry

Human papillomavirus 5 reference strain

VE7_HPV05 Protein E7

1 entry

Human papillomavirus 56 reference strain

VE7_HPV56 Protein E7

1 entry

Human papillomavirus 7 reference strain

VE7_HPV07 Protein E7

1 entry

Human papillomavirus 9 reference strain

VE7_HPV09 Protein E7

1 entry

Human papillomavirus type 1 (Human papillomavirus type 1a) reference strain

VE7_HPV1 Protein E7

pdb 2B9D

1 entry

Human papillomavirus type 10 reference strain

VE7_HPV10 Protein E7

1 entry

Human papillomavirus type 16 reference strain

VE7_HPV16 Protein E7

pdb 4YOZ; 6APN; 7SQP; 7SR0; 7SR3; 7SR4; 7SSH; 7ST3

1 entry

Human papillomavirus type 18 reference strain

VE7_HPV18 Protein E7

pdb 6IWD

1 entry

Human papillomavirus type 26 reference strain

VE7_HPV26 Protein E7

1 entry

Human papillomavirus type 32 reference strain

VE7_HPV32 Protein E7

1 entry

Human papillomavirus type 34 reference strain

VE7_HPV34 Protein E7

1 entry

Human papillomavirus type 41 reference strain

VE7_HPV41 Protein E7

1 entry

Human papillomavirus type 48 reference strain

VE7_HPV48 Protein E7

1 entry

Human papillomavirus type 50 reference strain

VE7_HPV50 Protein E7

1 entry

Human papillomavirus type 54 reference strain

VE7_HPV54 Protein E7

1 entry

Human papillomavirus type 60 reference strain

VE7_HPV60 Protein E7

1 entry

Human papillomavirus type 61 reference strain

VE7_HPV61 Protein E7

1 entry

Human papillomavirus type 63 reference strain

VE7_HPV63 Protein E7

1 entry

Human papillomavirus type 70 reference strain

VE7_HPV70 Protein E7

1 entry

JC polyomavirus (JCPyV) (JCV) reference strain

LT_POVJC Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

pdb 4LIF; 4LMD; 4NBP; 5CYN; 5J40; 5J47; 5J4V; 5J4Y; 8SUD

1 entry

Macaca mulata papillomavirus 1 (Rhpv 1) (Rhesus papillomavirus type 1) reference strain

VE7_MMPV1 Protein E7

1 entry

Maize streak virus genotype A (isolate South Africa) (MSV) reference strain

REPA_MSVS Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Maize streak virus genotype D (isolate Raw) (MSV) reference strain

REPA_MSVRA Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Miscanthus streak virus (isolate 91) (MiSV) reference strain

REPA_MISV9 Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Murid herpesvirus 1 (strain Smith) (MuHV-1) (Mouse cytomegalovirus) reference strain

VIE3_MUHVS Immediate-early protein 3 (IE3)

1 entry

Murine minute virus (strain MVM prototype) (MVM) (Murine minute virus (strain MVM(p))) reference strain

NS1_MUMIP Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

pdb 3WRN; 3WRO; 3WRQ; 3WRR; 3WRS; 4PP4; 4R94

1 entry

Murine polyomavirus (strain A2) (MPyV) reference strain

LT_POVMA Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Odocoileus virginianus papillomavirus 1 (DPV) (Deer papillomavirus) reference strain

VE7_OVPVD Protein E7

1 entry

Panicum streak virus (isolate Kenya) (PanSV) reference strain

REPA_PASVK Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Pygmy chimpanzee papillomavirus type 1 (PCPV-1) reference strain

VE7_PCPV1 Protein E7

1 entry

Simian virus 40 (SV40) reference strain

LT_SV40 Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

pdb 1EJL; 1GH6; 1N25; 1Q1S; 1Q1T; 1SVL; 1SVM; 1SVO; 1TBD; 1Z1D; 2FUF; 2H1L; 2IF9; 2IPR; 2ITJ; 2ITL; 2NL8; 2NTC; 2TBD; 3QK2; 3QN2; 4E2I; 4FGN; 4GDF; 4RXH; 5D9I; 9EVH; 9EVP; 9EXD; 9F3T; 9F3U; 9F5I; 9F73; 9F74; 9F75; 9F7N; 9F9N; 9F9O; 9F9W; 9F9X; 9FA1; 9FA2; 9FB0; 9FB4; 9FB5; 9FB6; 9KAE; 9KAK

1 entry

Squirrel monkey polyomavirus reference strain

LT_POVSM Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Sugarcane streak virus (isolate South Africa) (SSV) (Sugarcane streak virus (isolate Natal)) reference strain

REPA_SSVN Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

WU polyomavirus (WUPyV) reference strain

LT_POVWU Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

pdb 8TUS

1 entry

Wheat dwarf virus (isolate Sweden) (WDV) reference strain

REPA_WDVS Replication-associated protein A (RepA) (EC 3.1.21.-)

3 entries

Epstein-Barr virus (strain GD1) (HHV-4) (Human gammaherpesvirus 4)

Select_allDeselect_all
CEP2_EBVG Cytoplasmic envelopment protein 2 (Tegument protein BGLF2)
EAD_EBVG DNA polymerase processivity factor BMRF1 (Early Antigen Diffused) (EA-D) (Polymerase accessory ...
EBNA6_EBVG Epstein-Barr nuclear antigen 6 (EBNA-6) (EBV nuclear antigen 6) (Epstein-Barr nuclear antigen 3C) ...

3 entries

Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)

Select_allDeselect_all
VIE1_HCMVT Immediate early protein IE1 (IE1) (55 kDa immediate-early protein 1) (IE1p72) (IE72)

pdb 4QRU; 5E5A

VIE2_HCMVT Viral transcription factor IE2 (IE2) (Protein UL122)
IE247_HCMVT 45 kDa immediate-early protein 2 (IE2)

1 entry

BK polyomavirus (BKPyV) (Human polyomavirus 1)

LT_POVBK Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

BK polyomavirus (strain AS) (BKPyV)

LT_POVBA Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Bos taurus papillomavirus 2 (Bovine papillomavirus 2)

VE7_BPV2 Protein E7

1 entry

Bos taurus papillomavirus 4 (Bovine papillomavirus 4)

VE7_BPV4 Protein E7

1 entry

Bos taurus papillomavirus 6 (Bovine papillomavirus 6)

VE7_BPV6 Protein E7

1 entry

Canine adenovirus serotype 1 (strain CLL) (CAdV-1) (Canine adenovirus 1 (strain CLL))

E1A_ADECC Early E1A protein (Early E1A 25 kDa protein)

1 entry

Canine adenovirus serotype 1 (strain Glaxo) (CAdV-1) (Canine adenovirus 1 (strain Glaxo))

E1A_ADECG Early E1A protein (Early E1A 20 kDa protein)

1 entry

Canine adenovirus serotype 1 (strain RI261) (CAdV-1) (Canine adenovirus 1 (strain RI261))

E1A_ADECR Early E1A protein (Early E1A 20 kDa protein)

1 entry

Canine adenovirus serotype 2 (CAdV-2) (Canine adenovirus 2)

E1A_ADEC2 Early E1A protein (Early E1A 20 kDa protein)

1 entry

Canine parvovirus type 2 (isolate Dog/United States/CPV-N/1978) (CPV-2)

NS1_PAVCN Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Cottontail rabbit papillomavirus (strain Washington B) (CRPV) (Papillomavirus sylvilagi)

VE7_CRPVW Protein E7

1 entry

Feline panleukopenia virus (strain 193) (FPV)

NS1_FPV19 Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Hamster parvovirus H1

NS1_PAVHH Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Hepatitis C virus genotype 1a (isolate 1) (HCV)

POLG_HCV1 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1RTL; 2A4G; 2GVF; 3EYD; 3HKW; 3KN2; 3QGH; 3QGI; 3RC4; 3RC5; 3SU4; 6MVO; 6N4N; 6VDO; 7MM3; 7MM4; 7MM9; 7MMA; 7MMB; 7MMC; 7MMD; 7MME; 7MMK; 7MML

1 entry

Hepatitis C virus genotype 1b (isolate BK) (HCV)

POLG_HCVBK Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1A1Q; 1BT7; 1C2P; 1CSJ; 1CU1; 1GX5; 1GX6; 1JXP; 1NHU; 1NHV; 1NS3; 1OS5; 1QUV; 2AWZ; 2AX0; 2AX1; 2BRK; 2BRL; 2DXS; 2GIQ; 2GIR; 2HAI; 2HWH; 2HWI; 2I1R; 2JC0; 2JC1; 2O5D; 2WCX; 2WHO; 2WRM; 2XWY; 2ZKU; 3BR9; 3BSA; 3BSC; 3CDE; 3CIZ; 3CJ0; 3CJ2; 3CJ3; 3CJ4; 3CJ5; 3CO9; 3CVK; 3CWJ; 3D28; 3D5M; 3E51; 3FQK; 3FRZ; 3G86; 3GYN; 3H2L; 3H59; 3H5S; 3H5U; 3H98; 3IGV; 3MF5; 3RVB; 3UA7; 3UDL; 3VQS; 4A92; 4B6E; 4B6F; 4B71; 4B73; 4B74; 4B75; 4B76; 4DGV; 4DGY; 4EO6; 4EO8; 4IH5; 4IH6; 4IH7; 4K8B; 4KAI; 4KB7; 4KBI; 4KE5; 4MIA; 4MIB; 4MK7; 4MK8; 4MK9; 4MKA; 4MKB; 4TN2; 4WXP; 5FPS; 5FPT; 5FPY; 5KZP; 5W2E; 6MVP; 6W4G; 8OHM

1 entry

Hepatitis C virus genotype 1b (isolate Con1) (HCV)

POLG_HCVCO Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1ZH1; 2JY0; 2KWT; 2KWZ; 3FQL; 3FQM; 3FQQ; 3KN2; 3KQH; 3KQK; 3KQL; 3KQN; 3KQU; 3Q0Z; 3QGD; 3QGE; 3QGF; 3QGG; 4NLD; 4U01; 5E4F; 5PZK; 5PZL; 5PZM; 5PZN; 5PZO; 5PZP; 5TRH; 5TRI; 5TRJ; 5TRK; 5TWN

1 entry

Hepatitis C virus genotype 1b (isolate HC-J1) (HCV)

POLG_HCVJ1 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 2KNU; 3MRG; 3MRH; 3MRI; 3MRJ; 3MRL

1 entry

Hepatitis C virus genotype 1b (isolate HC-JT) (HCV)

POLG_HCVJT Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate HCR6) (HCV)

POLG_HCVR6 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate Japanese) (HCV)

POLG_HCVJA Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1DXP; 1DY8; 1DY9; 1W3C; 2K8J; 3OYP; 3P8N; 3P8O; 4A1T; 4A1V; 4A1X; 4I31; 4I32; 4I33; 4JMY; 4KTC

1 entry

Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)

POLG_HCVTW Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1N64; 2ZJO

1 entry

Hepatitis C virus genotype 1b (strain HC-J4) (HCV)

POLG_HCVJ4 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1NB4; 1NB6; 1NB7; 2F55; 2MTS; 2XHU; 2XHV; 2XHW; 2YOJ; 3CSO; 3GNV; 3GNW; 3GOL; 3HKY; 3LKH; 3MWV; 3MWW; 3SKA; 3SKE; 3SKH; 3TYQ; 3TYV; 3U4O; 3U4R; 3UPH; 3UPI; 4DRU; 4EAW; 4GMC; 4IZ0; 4J02; 4J04; 4J06; 4J08; 4J0A; 4JJS; 4JJU; 4JTW; 4JTY; 4JTZ; 4JU1; 4JU2; 4JU3; 4JU4; 4JU6; 4JU7; 4JVQ; 4JY0; 4JY1; 4MZ4; 4OOW; 4RY4; 4RY5; 4RY6; 4RY7; 5CZB; 5NPH; 5NPI

1 entry

Hepatitis C virus genotype 1c (isolate HC-G9) (HCV)

POLG_HCVH9 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1c (isolate India) (HCV)

POLG_HCVIN Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2a (isolate HC-J6) (HCV)

POLG_HCVJ6 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1YUY; 1YV2; 1YVX; 1YVZ; 2XWH; 4ADP

1 entry

Hepatitis C virus genotype 2a (isolate JFH-1) (HCV)

POLG_HCVJF Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 2KZQ; 2LIF; 2LVG; 2XXD; 2XYM; 3I5K; 4AEP; 4AEX; 4E76; 4E78; 4E7A; 4J1V; 4OBC; 4WT9; 4WTA; 4WTC; 4WTD; 4WTE; 4WTF; 4WTG; 4WTI; 4WTJ; 4WTK; 4WTL; 4WTM; 5NPJ; 5QJ0; 5QJ1; 5TWM; 5UJ2; 6HT4

1 entry

Hepatitis C virus genotype 2b (isolate HC-J8) (HCV)

POLG_HCVJ8 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 1XCQ; 1XCT; 1XF5; 3GSZ; 3HVO

1 entry

Hepatitis C virus genotype 2b (isolate JPUT971017) (HCV)

POLG_HCVJP Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2c (isolate BEBE1) (HCV)

POLG_HCVBB Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2k (isolate VAT96) (HCV)

POLG_HCVVA Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3a (isolate NZL1) (HCV)

POLG_HCVNZ Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 6P6S

1 entry

Hepatitis C virus genotype 3a (isolate k3a) (HCV)

POLG_HCVK3 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3b (isolate Tr-Kj) (HCV)

POLG_HCVTR Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3k (isolate JK049) (HCV)

POLG_HCVJK Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 4a (isolate ED43) (HCV)

POLG_HCVED Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 6P6Z

1 entry

Hepatitis C virus genotype 5a (isolate EUH1480) (HCV)

POLG_HCVEV Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

pdb 2M6X

1 entry

Hepatitis C virus genotype 5a (isolate SA13) (HCV)

POLG_HCVSA Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6a (isolate 6a33) (HCV)

POLG_HCV6A Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6a (isolate EUHK2) (HCV)

POLG_HCVEU Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6b (isolate Th580) (HCV)

POLG_HCVT5 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6d (isolate VN235) (HCV)

POLG_HCVVN Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6g (isolate JK046) (HCV)

POLG_HCVJL Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6h (isolate VN004) (HCV)

POLG_HCVVP Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6k (isolate VN405) (HCV)

POLG_HCVVO Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Human T-cell leukemia virus 1 (isolate Melanesia mel5 subtype C) (HTLV-1)

TAX_HTL1L Protein Tax-1 (Protein X-LOR) (Trans-activating transcriptional regulatory protein of HTLV-1)

1 entry

Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1)

TAX_HTL1F Protein Tax-1 (Protein X-LOR) (Trans-activating transcriptional regulatory protein of HTLV-1)

pdb 1BD2; 4E5X; 4FTV

1 entry

Human adenovirus B serotype 7 (HAdV-7) (Human adenovirus 7)

E1A_ADE07 Early E1A protein (Early E1A 28 kDa protein)

1 entry

Human adenovirus E serotype 4 (HAdV-4) (Human adenovirus 4)

E1A_ADE04 Early E1A protein (Early E1A 28 kDa protein)

1 entry

Human adenovirus F serotype 41 (HAdV-41) (Human adenovirus 41)

E1A_ADE41 Early E1A protein (Early E1A 27 kDa protein)

1 entry

Human herpesvirus 1 (strain HFEM) (HHV-1) (Human herpes simplex virus 1)

ICP27_HHV1E mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27)

pdb 6FAD

1 entry

Human papillomavirus 12

VE7_HPV12 Protein E7

1 entry

Human papillomavirus 13

VE7_HPV13 Protein E7

1 entry

Human papillomavirus 17

VE7_HPV17 Protein E7

1 entry

Human papillomavirus 19

VE7_HPV19 Protein E7

1 entry

Human papillomavirus 20

VE7_HPV20 Protein E7

1 entry

Human papillomavirus 25

VE7_HPV25 Protein E7

1 entry

Human papillomavirus 28

VE7_HPV28 Protein E7

1 entry

Human papillomavirus 33

VE7_HPV33 Protein E7

1 entry

Human papillomavirus 36

VE7_HPV36 Protein E7

1 entry

Human papillomavirus 37

VE7_HPV37 Protein E7

1 entry

Human papillomavirus 38

VE7_HPV38 Protein E7

1 entry

Human papillomavirus 40

VE7_HPV40 Protein E7

1 entry

Human papillomavirus 42

VE7_HPV42 Protein E7

1 entry

Human papillomavirus 45

VE7_HPV45 Protein E7

pdb 2EWL; 2F8B

1 entry

Human papillomavirus 47

VE7_HPV47 Protein E7

1 entry

Human papillomavirus 51

VE7_HPV51 Protein E7

1 entry

Human papillomavirus 52

VE7_HPV52 Protein E7

1 entry

Human papillomavirus 57

VE7_HPV57 Protein E7

1 entry

Human papillomavirus 58

VE7_HPV58 Protein E7

1 entry

Human papillomavirus 65

VE7_HPV65 Protein E7

1 entry

Human papillomavirus 66

VE7_HPV66 Protein E7

1 entry

Human papillomavirus 68

VE7_HPV68 Protein E7

1 entry

Human papillomavirus 69

VE7_HPV69 Protein E7

1 entry

Human papillomavirus type 2a

VE7_HPV2A Protein E7

1 entry

Human papillomavirus type 49

VE7_HPV49 Protein E7

1 entry

Human papillomavirus type 53

VE7_HPV53 Protein E7

1 entry

Human papillomavirus type 55

VE7_HPV55 Protein E7

1 entry

Human papillomavirus type 5b

VE7_HPV5B Protein E7

1 entry

Human papillomavirus type 6a

VE7_HPV6A Protein E7

1 entry

Human papillomavirus type 6b

VE7_HPV6B Protein E7

1 entry

Human papillomavirus type 8

VE7_HPV08 Protein E7

1 entry

Human papillomavirus type 94

VE7_HPV94 Protein E7

1 entry

Human papillomavirus type ME180

VE7_HPVME Protein E7

1 entry

KI polyomavirus (isolate Stockholm 350) (KIPyV)

LT_POVKI Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

KI polyomavirus (isolate Stockholm 380) (KIPyV)

LT_POVK3 Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

KI polyomavirus (isolate Stockholm 60) (KIPyV)

LT_POVK6 Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

pdb 8Q8K

1 entry

Maize streak virus genotype A (isolate Kenya) (MSV)

REPA_MSVK Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Maize streak virus genotype A (isolate Nigeria) (MSV)

REPA_MSVN Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Maize streak virus genotype B (isolate Tas) (MSV)

REPA_MSVTA Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Maize streak virus genotype C (isolate Set) (MSV)

REPA_MSVSE Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Maize streak virus genotype E (isolate Pat) (MSV)

REPA_MSVPA Replication-associated protein A (RepA) (EC 3.1.21.-)

1 entry

Mink enteritis virus (strain Abashiri) (MEV)

NS1_MEVA Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Murine adenovirus A serotype 1 (MAdV-1) (Murine adenovirus 1)

E1A_ADEM1 Early E1A 21 kDa protein

1 entry

Murine minute virus (strain MVMi) (MVM) (Murine parvovirus)

NS1_MUMIM Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Murine polyomavirus (strain A3) (MPyV)

LT_POVM3 Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

pdb 1FAF

1 entry

Murine polyomavirus (strain BG) (MPyV)

LT_POVBG Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

pdb 4FB3

1 entry

Murine polyomavirus (strain Crawford small-plaque) (MPyV)

LT_POVMC Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Murine polyomavirus (strain Kilham) (MPyV) (Murine pneumotropic virus)

LT_POVMK Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Mus musculus polyomavirus 1 (MPyV)

LT_POVM1 Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Parvovirus LuIII

NS1_PAVL3 Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Porcine parvovirus (strain Kresse) (PPV)

NS1_PAVPK Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Porcine parvovirus (strain NADL-2) (PPV)

NS1_PAVPN Initiator protein NS1 (NS1) (EC 3.1.21.-) (EC 3.6.4.12) (NCVP1) (Non-capsid protein NS-1) ...

1 entry

Simian adenovirus serotype 7 (SAdV-7) (Simian adenovirus 7)

E1A_ADES7 Early E1A protein (Early E1A 28 kDa protein)

1 entry

Simian virus 12 (strain wt100) (SV-12) (Baboon polyomavirus 1)

LT_POVS1 Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

1 entry

Tobacco yellow dwarf virus (strain Australia) (TYDV)

REPA_TYDVA Replication-associated protein A (RepA) (EC 3.1.21.-)