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Polyomaviridae (taxid:151341)

VIRION

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Non-enveloped capsid with a T=7d icosahedral symmetry, about 50 nm in diameter.
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GENOME

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Circular dsDNA about 5 kb in size, associated with cellular histones in a chromatin-like complex. Encodes for 5-9 proteins.
On rare non-specific recombination, the viral genome can be integrated in host chromosome. This inactivates the integrated virus but can give the host cell a replicative advantage sometimes leading to malignant tumours.

GENE EXPRESSION

Transcription is nuclear, in two phases; early (replication), late (virion assembly/exit). 5-9 proteins are expressed from the two pre-MRNA by alternative splicing. All genes are transcribed by host RNA pol II.

REPLICATION

NUCLEAR

  1. Attachement of the viral proteins to host receptors triggers lipid-mediated endocytosis of the virus into the host cell.
  2. Virion transits through endoplasmic reticulum where host protein disulfide isomerases rearrange its capsid structure
  3. Export of misfolded virion to the cytoplasm possibly through host ERAD pathway
  4. Loss of VP1 in the low-calcium conditions of the cytosol
  5. Import of genomic DNA into host nucleus.
  6. Transcription of early genes (LT and sT genes)
  7. Replication of the DNA genome in the nucleus.
  8. Transcription of late genes encoding for structural proteins (VP1, VP2 and VP3).
  9. Assembly of new virions in nuclear viral factories.
  10. Virions are released by lysis of the cell.
DB LINKS image image

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TAXONOMY Group I: dsDNA viruses
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cossaviricota
Class: Papovaviricetes
Order: Sepolyvirales
Family: Polyomaviridae
Genus: Alphapolyomavirus
Betapolyomavirus
Deltapolyomavirus
Gammapolyomavirus
VIRUS
REFERENCE STRAIN Simian virus 40
Sequence | Genome assembly | Proteome

Host

NATURAL HOSTS Mammals and birds
CELL TROPISM JCPyV: respiratory system, kidneys, or brain.
BKPyV: respiratory system, latency in kidneys.
INTERACTIONS Cell receptors: SV-40: Gangliosides
JCPyV: terminal alpha(2,6)-linked sialic acids
BFPyV and MPyV: alpha(2,3)-linked sialic acids
Host-virus interaction

Ecology and disease

GEOGRAPHY Worldwide
ASSOCIATED DISEASES JCPyV: progressive multifocal leukoencephalopathy.
BKPyV: mild respiratory infection.
Some cancers may be associated with polyoma viruses
In birds: Budgerigar Fledgling Disease
TRANSMISSION BFPyV: contaminated feces and aerosolized dust. Egg transmission.
VACCINE None
ANTIVIRAL DRUGS None

Host-virus interaction

Cell-cycle modulation

The large T antigen binds to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53 and induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.

GENERAL Back to polyomaviridae page
NATURAL HOSTS Mammals and birds
CELL TROPISM JCPyV: respiratory system, kidneys, or brain.
INTERACTIONS Cell receptors SV-40: Gangliosides
JCPyV: terminal alpha(2,6)-linked sialic acids
BFPyV and MPyV: alpha(2,3)-linked sialic acids
ASSOCIATED DISEASES JCPyV: progressive multifocal leukoencephalopathy.
BKPyV: mild respiratory infection.
Some cancers may be associated with polyoma viruses
In birds: Budgerigar Fledgling Disease
TRANSMISSION BFPyV: contaminated feces and aerosolized dust. Egg transmission.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

91 entries grouped by protein

7 entries

Agnoprotein (Agno)

Select_allDeselect_all
AGNO_POVBO
Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1) reference strain

Bovine agnoprotein (Agno)

AGNO_POVJC
JC polyomavirus (JCPyV) (JCV) reference strain

pdb 2MJ2; 5NHQ

AGNO_POVSM
Squirrel monkey polyomavirus reference strain

Squirrel monkey agnoprotein (Agno)

AGNO_SV40
Simian virus 40 (SV40) reference strain

Agnoprotein

AGNO_POVBA
BK polyomavirus (strain AS) (BKPyV)
AGNO_POVBK
BK polyomavirus (BKPyV) (Human polyomavirus 1)
AGNO_POVS1
Simian virus 12 (strain wt100) (SV-12) (Baboon polyomavirus 1)

1 entry

Avian agnoprotein 1a (Agno-1a)

AGNO1_BFPYV
Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1)

1 entry

Avian agnoprotein 2b (Agno-2b)

AGNO2_BFPYV
Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1) reference strain

20 entries

Large T antigen (LT) (LT-AG) (EC 5.6.2.4) (DNA 3'-5' helicase large T antigen)

Select_allDeselect_all
LT_BFPYV
Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1) reference strain
LT_POVBO
Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1) reference strain
LT_POVHA
Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1) reference strain
LT_POVJC
JC polyomavirus (JCPyV) (JCV) reference strain

pdb 4LIF; 4LMD; 4NBP; 5CYN; 5J40; 5J47; 5J4V; 5J4Y; 8SUD

LT_POVLY
B-lymphotropic polyomavirus (LPV) reference strain
LT_POVMA
Murine polyomavirus (strain A2) (MPyV) reference strain
LT_POVSM
Squirrel monkey polyomavirus reference strain
LT_POVWU
WU polyomavirus (WUPyV) reference strain

pdb 8TUS

LT_SV40
Simian virus 40 (SV40) reference strain

pdb 1EJL; 1GH6; 1N25; 1Q1S; 1Q1T; 1SVL; 1SVM; 1SVO; 1TBD; 1Z1D; 2FUF; 2H1L; 2IF9; 2IPR; 2ITJ; 2ITL; 2NL8; 2NTC; 2TBD; 3QK2; 3QN2; 4E2I; 4FGN; 4GDF; 4RXH; 5D9I; 9EVH; 9EVP; 9EXD; 9F3T; 9F3U; 9F5I; 9F73; 9F74; 9F75; 9F7N; 9F9N; 9F9O; 9F9W; 9F9X; 9FA1; 9FA2; 9FB0; 9FB4; 9FB5; 9FB6; 9KAE; 9KAK

LT_POVBA
BK polyomavirus (strain AS) (BKPyV)
LT_POVBG
Murine polyomavirus (strain BG) (MPyV)

pdb 4FB3

LT_POVBK
BK polyomavirus (BKPyV) (Human polyomavirus 1)
LT_POVK3
KI polyomavirus (isolate Stockholm 380) (KIPyV)
LT_POVK6
KI polyomavirus (isolate Stockholm 60) (KIPyV)

pdb 8Q8K

LT_POVKI
KI polyomavirus (isolate Stockholm 350) (KIPyV)
LT_POVM1
Mus musculus polyomavirus 1 (MPyV)
LT_POVM3
Murine polyomavirus (strain A3) (MPyV)

pdb 1FAF

LT_POVMC
Murine polyomavirus (strain Crawford small-plaque) (MPyV)
LT_POVMK
Murine polyomavirus (strain Kilham) (MPyV) (Murine pneumotropic virus)
LT_POVS1
Simian virus 12 (strain wt100) (SV-12) (Baboon polyomavirus 1)

6 entries

Middle T antigen (MT) (MT-AG)

Select_allDeselect_all
MT_POVHA
Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1) reference strain

pdb 1AOT; 1AOU; 1LCJ; 1SPS; 4U1P

MT_POVMA
Murine polyomavirus (strain A2) (MPyV) reference strain

pdb 1YGU

MT_POVBG
Murine polyomavirus (strain BG) (MPyV)

pdb 1FU5; 1QJB

MT_POVM1
Mus musculus polyomavirus 1 (MPyV)
MT_POVM3
Murine polyomavirus (strain A3) (MPyV)
MT_POVMC
Murine polyomavirus (strain Crawford small-plaque) (MPyV)

1 entry

SV40 early leader protein (SELP)

SELP_SV40
Simian virus 40 (SV40) reference strain

18 entries

Small t antigen (ST) (ST-AG)

Select_allDeselect_all
ST_BFPYV
Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1) reference strain
ST_POVBO
Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1) reference strain
ST_POVHA
Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1) reference strain
ST_POVJC
JC polyomavirus (JCPyV) (JCV) reference strain
ST_POVLY
B-lymphotropic polyomavirus (LPV) reference strain
ST_POVMA
Murine polyomavirus (strain A2) (MPyV) reference strain
ST_POVSM
Squirrel monkey polyomavirus reference strain
ST_POVWU
WU polyomavirus (WUPyV) reference strain
ST_SV40
Simian virus 40 (SV40) reference strain

pdb 2PF4; 2PKG

ST_POVBA
BK polyomavirus (strain AS) (BKPyV)
ST_POVBK
BK polyomavirus (BKPyV) (Human polyomavirus 1)
ST_POVK3
KI polyomavirus (isolate Stockholm 380) (KIPyV)
ST_POVK6
KI polyomavirus (isolate Stockholm 60) (KIPyV)
ST_POVKI
KI polyomavirus (isolate Stockholm 350) (KIPyV)
ST_POVM3
Murine polyomavirus (strain A3) (MPyV)
ST_POVMC
Murine polyomavirus (strain Crawford small-plaque) (MPyV)
ST_POVMK
Murine polyomavirus (strain Kilham) (MPyV) (Murine pneumotropic virus)
ST_POVS1
Simian virus 12 (strain wt100) (SV-12) (Baboon polyomavirus 1)

19 entries

Major capsid protein VP1 (Major structural protein VP1)

Select_allDeselect_all
VP1_BFPYV
Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1) reference strain

pdb 3IYS

VP1_POVBO
Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1) reference strain
VP1_POVJC
JC polyomavirus (JCPyV) (JCV) reference strain

pdb 3NXD; 3NXG; 4JCD; 4JCE; 4JCF; 4WDY; 4WDZ; 4WE0; 4X14; 4X15; 4X16; 4X17; 7PA6; 7PA8; 7PA9; 7PAA; 7ZIL; 7ZIM; 7ZIN; 7ZIO

VP1_POVMA
Murine polyomavirus (strain A2) (MPyV) reference strain
VP1_POVSM
Squirrel monkey polyomavirus reference strain
VP1_POVWU
WU polyomavirus (WUPyV) reference strain

pdb 3S7X

VP1_SV40
Simian virus 40 (SV40) reference strain

pdb 1SVA; 3BWQ; 3BWR

VP1_POVBA
BK polyomavirus (strain AS) (BKPyV)
VP1_POVBK
BK polyomavirus (BKPyV) (Human polyomavirus 1)

pdb 4MJ0; 4MJ1; 5FUA; 6ESB; 6GG0; 7B69; 7B6A; 7B6C; 7PA7; 7ZIP; 8AGH; 8AGO; 8AH0; 8AH1

VP1_POVHA
Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1)
VP1_POVK3
KI polyomavirus (isolate Stockholm 380) (KIPyV)
VP1_POVK6
KI polyomavirus (isolate Stockholm 60) (KIPyV)

pdb 3S7V

VP1_POVKI
KI polyomavirus (isolate Stockholm 350) (KIPyV)
VP1_POVLY
B-lymphotropic polyomavirus (LPV)

pdb 4MBX; 4MBY; 4MBZ

VP1_POVM3
Murine polyomavirus (strain A3) (MPyV)
VP1_POVMC
Murine polyomavirus (strain Crawford small-plaque) (MPyV)
VP1_POVMK
Murine polyomavirus (strain Kilham) (MPyV) (Murine pneumotropic virus)
VP1_POVMP
Murine polyomavirus (strain P16 small-plaque) (MPyV)

Capsid protein VP1

pdb 1CN3; 1SID; 1SIE; 1VPN; 1VPS; 5CPU; 5CPW; 5CPX; 5CPY; 5CPZ; 5CQ0; 7K25

VP1_POVS1
Simian virus 12 (strain wt100) (SV-12) (Baboon polyomavirus 1)

18 entries

Minor capsid protein VP2 (Minor structural protein VP2)

Select_allDeselect_all
VP2_BFPYV
Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1) reference strain
VP2_POVBO
Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1) reference strain
VP2_POVHA
Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1) reference strain
VP2_POVJC
JC polyomavirus (JCPyV) (JCV) reference strain
VP2_POVLY
B-lymphotropic polyomavirus (LPV) reference strain
VP2_POVMA
Murine polyomavirus (strain A2) (MPyV) reference strain
VP2_POVMK
Murine polyomavirus (strain Kilham) (MPyV) (Murine pneumotropic virus) reference strain
VP2_POVSM
Squirrel monkey polyomavirus reference strain
VP2_POVWU
WU polyomavirus (WUPyV) reference strain
VP2_SV40
Simian virus 40 (SV40) reference strain
VP2_POVBA
BK polyomavirus (strain AS) (BKPyV)
VP2_POVBK
BK polyomavirus (BKPyV) (Human polyomavirus 1)

pdb 6ESB

VP2_POVK3
KI polyomavirus (isolate Stockholm 380) (KIPyV)
VP2_POVK6
KI polyomavirus (isolate Stockholm 60) (KIPyV)
VP2_POVKI
KI polyomavirus (isolate Stockholm 350) (KIPyV)
VP2_POVM3
Murine polyomavirus (strain A3) (MPyV)
VP2_POVMC
Murine polyomavirus (strain Crawford small-plaque) (MPyV)

pdb 1CN3

VP2_POVS1
Simian virus 12 (strain wt100) (SV-12) (Baboon polyomavirus 1)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Adelie penguin polyomavirus taxid:1590650

Protein ModelArchive
Large T antigen ma-jd-viral-21151
Minor capsid protein ma-jd-viral-31174
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29766
Small T antigen ma-jd-viral-16533
VP1 ma-jd-viral-14763

African elephant polyomavirus 1 taxid:1399914

Protein ModelArchive
Large T antigen ma-jd-viral-21194
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14806
Minor capsid protein ma-jd-viral-31182
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29807
Small T antigen ma-jd-viral-16625

Alphapolyomavirus apaniscus taxid:1236391

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14775
Large T antigen ma-jd-viral-21185
Minor capsid protein ma-jd-viral-29844
Small T antigen ma-jd-viral-16548

Alphapolyomavirus chlopygerythrus taxid:1891719

Protein ModelArchive
Large T antigen ma-jd-viral-21219
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48379
Small T antigen ma-jd-viral-16545
VP1 major capsid protein ma-jd-viral-14755

Alphapolyomavirus molossi taxid:1606504

Protein ModelArchive
Large T-antigen ma-jd-viral-21172
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48377
Small t-antigen ma-jd-viral-16603
VP1 structural protein ma-jd-viral-14810

Alphapolyomavirus quartipanos taxid:1891736

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14785
Large T antigen ma-jd-viral-21121
Minor capsid protein ma-jd-viral-29757
Small T antigen ma-jd-viral-16567

Alphapolyomavirus quintipanos taxid:1891737

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14761
Large T antigen ma-jd-viral-21214
Minor capsid protein ma-jd-viral-29808
Small T antigen ma-jd-viral-16576

Alphapolyomavirus septipanos taxid:1891739

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14712
Large T antigen ma-jd-viral-21178
Minor capsid protein ma-jd-viral-31166
Small T antigen ma-jd-viral-16628

Alphapolyomavirus sextipanos taxid:1891738

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14705
Large T antigen ma-jd-viral-21119
Minor capsid protein ma-jd-viral-31161
Small T antigen ma-jd-viral-16645

Alphapolyomavirus tertichlopygerythrus taxid:1891720

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14756
Large T antigen ma-jd-viral-21104
Minor capsid protein ma-jd-viral-31144
Minor capsid protein ma-jd-viral-29767
Small T antigen ma-jd-viral-16541

Alphapolyomavirus tertipanos taxid:1891735

Protein ModelArchive
Large T antigen ma-jd-viral-21111
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48364
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48392
Small T antigen ma-jd-viral-16592
VP1 ma-jd-viral-14707

BK polyomavirus taxid:1891762

Protein ModelArchive
Agnoprotein ma-jd-viral-59844
Agnoprotein (Agno) ma-jd-viral-59844
Capsid protein VP1 ma-jd-viral-14726
Large T antigen (LT) (LT-AG) (EC 3.6.4.-) ma-jd-viral-21153
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14726
Minor capsid protein ma-jd-viral-29763
Minor capsid protein ma-jd-viral-29803
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29803
Small t antigen ma-jd-viral-16584
Small t antigen ma-jd-viral-16584
Small t antigen (ST) (ST-AG) ma-jd-viral-16584

Bank vole polyomavirus taxid:1737522

Protein ModelArchive
Large T antigen ma-jd-viral-21142
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14700
Small t antigen ma-jd-viral-16543
VP2 ma-jd-viral-37809
VP3 ma-jd-viral-38151

Bat polyomavirus 5a taxid:1623687

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14735
Large T antigen ma-jd-viral-21140
Minor capsid protein ma-jd-viral-29843
Small t antigen ma-jd-viral-16632

Bat polyomavirus 6a taxid:1623685

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14724
Large T antigen ma-jd-viral-21152
Minor capsid protein ma-jd-viral-31177
Small t antigen ma-jd-viral-16540

Bat polyomavirus 6b taxid:1623689

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14711
Large T antigen ma-jd-viral-21112
Minor capsid protein ma-jd-viral-31138
Small t antigen ma-jd-viral-16577

Bat polyomavirus 6c taxid:1623688

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14741
Large T antigen ma-jd-viral-21195
Minor capsid protein ma-jd-viral-31176
Small t antigen ma-jd-viral-16572

Bat polyomavirus 6d taxid:1623686

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14779
Large T antigen ma-jd-viral-21210
Minor capsid protein ma-jd-viral-31149
Small t antigen ma-jd-viral-16591

Betapolyomavirus calbifrons taxid:1236392

Protein ModelArchive
Large T antigen ma-jd-viral-21205
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14713
Minor capsid protein ma-jd-viral-31157
Small t antigen ma-jd-viral-16607

Betapolyomavirus cercopitheci taxid:1236395

Protein ModelArchive
Agnoprotein ma-jd-viral-59846
Capsid protein VP1 ma-jd-viral-14797
Large T antigen ma-jd-viral-21107
Minor capsid protein ma-jd-viral-29840
Small t antigen ma-jd-viral-16538

Betapolyomavirus equi taxid:1891761

Protein ModelArchive
Large T antigen ma-jd-viral-21162
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14798
Minor capsid protein ma-jd-viral-31152
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29774
Small t antigen ma-jd-viral-16598

Betapolyomavirus lepweddellii taxid:1925019

Protein ModelArchive
ALTO ma-jd-viral-66403
Agno ma-jd-viral-59788
Large T antigen ma-jd-viral-21124
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14796
Minor capsid protein ma-jd-viral-31155
Minor capsid protein ma-jd-viral-29823
Small t antigen ma-jd-viral-16642

Betapolyomavirus mafricanus taxid:1891769

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14793
Large T antigen ma-jd-viral-21116
Minor capsid protein ma-jd-viral-31146
Minor capsid protein ma-jd-viral-29761
Small t antigen ma-jd-viral-16624

Betapolyomavirus mastomysis taxid:1891768

Protein ModelArchive
Agnoprotein ma-jd-viral-49865
Capsid protein VP1 ma-jd-viral-14729
Large T antigen ma-jd-viral-21215
Minor capsid protein ma-jd-viral-31160
Minor capsid protein ma-jd-viral-29783
Small T antigen ma-jd-viral-16537

Betapolyomavirus ptedavyi taxid:1891773

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14811
Large T antigen ma-jd-viral-21120
Minor capsid protein ma-jd-viral-31165
Minor capsid protein ma-jd-viral-29798
Small t antigen ma-jd-viral-16593

Betapolyomavirus secuchlopygerythrus taxid:1891758

Protein ModelArchive
Agnoprotein ma-jd-viral-59842
Capsid protein VP1 ma-jd-viral-14737
Large T antigen ma-jd-viral-21201
Minor capsid protein ma-jd-viral-29796
Minor capsid protein ma-jd-viral-29825
Small t antigen ma-jd-viral-16550

Betapolyomavirus securanorvegicus taxid:1919247

Protein ModelArchive
ALTO ma-jd-viral-40309
Large T antigen ma-jd-viral-21212
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14777
Small t antigen ma-jd-viral-16549
VP2 ma-jd-viral-37808
VP3 ma-jd-viral-38152

Betapolyomavirus tertihominis taxid:1891764

Protein ModelArchive
Large T antigen ma-jd-viral-21159
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14807
Small t antigen ma-jd-viral-16626
VP2 ma-jd-viral-37811
VP3 ma-jd-viral-38153

Black sea bass polyomavirus 1 taxid:1572341

Protein ModelArchive
Large T antigen ma-jd-viral-21223
SLT ma-jd-viral-21225
SVP1 ma-jd-viral-14691
VP1 ma-jd-viral-14690
VP2 ma-jd-viral-38176

Bornean orang-utan polyomavirus taxid:1604874

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14768
Large T antigen ma-jd-viral-21134
Minor capsid protein ma-jd-viral-29836
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29770
Small T antigen ma-jd-viral-16633

Butcherbird polyomavirus taxid:1394033

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14719
Large T antigen ma-jd-viral-21145
Minor capsid protein ma-jd-viral-31175
Minor capsid protein ma-jd-viral-29835
Small T antigen ma-jd-viral-16536
VP4 ma-jd-viral-33992

California sea lion polyomavirus 1 taxid:715223

Protein ModelArchive
Large T antigen ma-jd-viral-21206
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14720
Minor capsid protein ma-jd-viral-31154
Minor capsid protein ma-jd-viral-29788
Putative agnoprotein ma-jd-viral-41574
Small t antigen ma-jd-viral-16578

Canary polyomavirus taxid:881945

Protein ModelArchive
Large T antigen ma-jd-viral-21149
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-31153
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29759
Small t antigen ma-jd-viral-16535
Virus protein 1 ma-jd-viral-14744

Chaerephon polyomavirus 1 taxid:1276181

Protein ModelArchive
Large T antigen ma-jd-viral-21109
Major structural protein VP1 ma-jd-viral-14764
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48373
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48394
Small T antigen ma-jd-viral-16596

Chimpanzee polyomavirus Bob taxid:2035845

Protein ModelArchive
Large T antigen ma-jd-viral-21166
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48363
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48384
Small T antigen ma-jd-viral-16562
VP1 protein ma-jd-viral-14734

Common vole polyomavirus taxid:1737523

Protein ModelArchive
Large T antigen ma-jd-viral-21132
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14758
Small t antigen ma-jd-viral-16539
VP2 ma-jd-viral-38155
VP3 ma-jd-viral-38154

Gammapolyomavirus corvi taxid:1891748

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14804
Large T antigen ma-jd-viral-21171
Minor capsid protein ma-jd-viral-29794
Minor capsid protein ma-jd-viral-29814
ORF-X ma-jd-viral-33993
Small t antigen ma-jd-viral-16532

Gammapolyomavirus pypyrrhula taxid:1891751

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14792
Large T antigen ma-jd-viral-21130
Minor capsid protein ma-jd-viral-31179
Minor capsid protein ma-jd-viral-29842
Putative ORF-X ma-jd-viral-64734
Putative small T antigen ma-jd-viral-16530

Gorilla gorilla gorilla polyomavirus 1 taxid:928214

Protein ModelArchive
Large T antigen ma-jd-viral-21154
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48386
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48391
Small T antigen ma-jd-viral-16653
VP1 ma-jd-viral-14721

Hamster polyomavirus taxid:1891729

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14736
Capsid protein VP1 ma-jd-viral-14736
Large T antigen ma-jd-viral-21170
Middle T antigen ma-jd-viral-09787
Middle T antigen (MT) (MT-AG) ma-jd-viral-09787
Minor capsid protein ma-jd-viral-31167
Minor capsid protein ma-jd-viral-29839
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-31167
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29839
Small T antigen ma-jd-viral-16594
Small t antigen (ST) (ST-AG) ma-jd-viral-16594

Human polyomavirus 6 taxid:746830

Protein ModelArchive
Large T antigen ma-jd-viral-21211
Large T antigen ma-jd-viral-21211
Small T antigen ma-jd-viral-16573
Small T antigen ma-jd-viral-16573
VP1 ma-jd-viral-14733
VP1 ma-jd-viral-14733
VP2 ma-jd-viral-37805
VP2 ma-jd-viral-37805
VP3 ma-jd-viral-38149
VP3 ma-jd-viral-38149

Human polyomavirus 7 taxid:746831

Protein ModelArchive
Large T antigen ma-jd-viral-21163
Small T antigen ma-jd-viral-16597
VP1 ma-jd-viral-14771
VP2 ma-jd-viral-37806
VP3 ma-jd-viral-38147

Human polyomavirus 9 taxid:943908

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14805
Capsid protein VP1 ma-jd-viral-14805
Gp5 protein (Small T antigen) ma-jd-viral-16566
Large T antigen ma-jd-viral-21136
Minor capsid protein ma-jd-viral-31159
Minor capsid protein ma-jd-viral-29778

JC polyomavirus taxid:10632

Protein ModelArchive
Agnoprotein ma-jd-viral-59845
Agnoprotein (Agno) ma-jd-viral-59845
Capsid protein VP1 ma-jd-viral-14787
Large T antigen ma-jd-viral-21189
Large T antigen (LT) (LT-AG) (EC 3.6.4.-) ma-jd-viral-21189
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14787
Minor capsid protein ma-jd-viral-29812
Minor capsid protein ma-jd-viral-29833
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29812
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29833
Small t antigen ma-jd-viral-16620
Small t antigen (ST) (ST-AG) ma-jd-viral-16620

MW polyomavirus taxid:1203539

Protein ModelArchive
Large T antigen ma-jd-viral-21143
Major capsid protein VP1 ma-jd-viral-14754
Minor capsid protein ma-jd-viral-29795
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29799
Small T antigen ma-jd-viral-16557

Macaca fascicularis polyomavirus 1 taxid:1236398

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14725
Large T antigen ma-jd-viral-21115
Minor capsid protein ma-jd-viral-31140
Small T antigen ma-jd-viral-16583

Marbled eel polyomavirus taxid:1662286

Protein ModelArchive
LO5 (ORF08R) ma-jd-viral-52029
ORF01L ma-jd-viral-21101
ORF01R ma-jd-viral-32472
ORF02L ma-jd-viral-58345
ORF02R ma-jd-viral-67141
ORF03L ma-jd-viral-34953
ORF03R ma-jd-viral-60989
ORF04L ma-jd-viral-65206
ORF04R ma-jd-viral-14029
ORF05L ma-jd-viral-65249
ORF05R ma-jd-viral-18061
ORF06R ma-jd-viral-64365
ORF07R ma-jd-viral-00110
ORF09R ma-jd-viral-32057
ORF10R ma-jd-viral-42963
ORF11R ma-jd-viral-45532

Meles meles polyomavirus 1 taxid:1608323

Protein ModelArchive
Large T antigen ma-jd-viral-21182
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14742
Minor capsid protein ma-jd-viral-31136
Minor capsid protein ma-jd-viral-29775
Small t antigen ma-jd-viral-16569

Merkel cell polyomavirus taxid:493803

Protein ModelArchive
Capsid protein (Major capsid protein) (VP1) ma-jd-viral-14698
Large T antigen (T antigen) ma-jd-viral-21218
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48371
Small T antigen (T antigen) ma-jd-viral-16589

Murine polyomavirus (strain BG) taxid:179241

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14714
Large T antigen (LT) (LT-AG) (EC 3.6.4.-) ma-jd-viral-21155
Middle T antigen (MT) (MT-AG) ma-jd-viral-09788
Minor capsid protein ma-jd-viral-29753
Minor capsid protein ma-jd-viral-29764
Small T antigen ma-jd-viral-16585

New Jersey polyomavirus-2013 taxid:1497391

Protein ModelArchive
Alternative T antigen ma-jd-viral-45454
Large T antigen ma-jd-viral-21220
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48361
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48378
Small T antigen ma-jd-viral-16553
VP1 ma-jd-viral-14739

Otomops polyomavirus KY156 taxid:2035998

Protein ModelArchive
Large T antigen ma-jd-viral-21131
Major structural protein VP1 ma-jd-viral-14773
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48365
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48397
Small T antigen ma-jd-viral-16652

Otomops polyomavirus KY157 taxid:2035999

Protein ModelArchive
Large T antigen ma-jd-viral-21216
Major structural protein VP1 ma-jd-viral-14704
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48362
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48389
Small T antigen ma-jd-viral-16579

Pan troglodytes troglodytes polyomavirus 1 taxid:1236400

Protein ModelArchive
Agnoprotein ma-jd-viral-59847
Capsid protein VP1 ma-jd-viral-14708
Large T antigen ma-jd-viral-21110
Minor capsid protein ma-jd-viral-29756
Minor capsid protein ma-jd-viral-29797
Small T antigen ma-jd-viral-16604

Pan troglodytes verus polyomavirus 1a taxid:928211

Protein ModelArchive
Large T antigen ma-jd-viral-21213
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48382
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48396
Small T antigen ma-jd-viral-16588
VP1 ma-jd-viral-14717

Pan troglodytes verus polyomavirus 8 taxid:1762023

Protein ModelArchive
Agnoprotein ma-jd-viral-59841
Capsid protein VP1 ma-jd-viral-14730
Large T antigen ma-jd-viral-21108
Minor capsid protein ma-jd-viral-29771
Minor capsid protein ma-jd-viral-29821
Small t antigen ma-jd-viral-16542

Piliocolobus rufomitratus polyomavirus 1 taxid:1236407

Protein ModelArchive
Large T antigen ma-jd-viral-21207
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48367
Small T antigen ma-jd-viral-16616
VP1 ma-jd-viral-14784

Polyomavirus sp. taxid:36362

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14716
Large T antigen ma-jd-viral-21150
Minor capsid protein ma-jd-viral-31148
Small T antigen ma-jd-viral-16558

Raccoon polyomavirus taxid:1219896

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14748
Large T antigen ma-jd-viral-21199
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48374
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48393
Small T antigen ma-jd-viral-21196

Rattus norvegicus polyomavirus 1 taxid:1679933

Protein ModelArchive
195 T antigen ma-jd-viral-16647
95 T antigen ma-jd-viral-34865
Capsid protein VP1 ma-jd-viral-14752
Large T antigen ma-jd-viral-21204
Middle T antigen ma-jd-viral-09790
Minor capsid protein ma-jd-viral-31178
Minor capsid protein ma-jd-viral-29815
Small T antigen ma-jd-viral-16618

STL polyomavirus taxid:1277649

Protein ModelArchive
Large T antigen ma-jd-viral-21148
Middle T antigen ma-jd-viral-16606
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-31151
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29782
Small T antigen ma-jd-viral-16599
VP1 ma-jd-viral-14774

Sea otter polyomavirus 1 taxid:1552409

Protein ModelArchive
Agnoprotein ma-jd-viral-60499
Capsid protein VP1 ma-jd-viral-14747
Large T antigen ma-jd-viral-21117
Minor capsid protein ma-jd-viral-31139
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29829
Small T antigen ma-jd-viral-16623

Sheep polyomavirus 1 taxid:1634381

Protein ModelArchive
ALTO ma-jd-viral-53700
Agno ma-jd-viral-40359
Capsid protein VP1 ma-jd-viral-14702
Large T antigen ma-jd-viral-21128
Minor capsid protein ma-jd-viral-31156
Minor capsid protein ma-jd-viral-29804
Small t antigen ma-jd-viral-16646

Sparus aurata polyomavirus 1 taxid:1885927

Protein ModelArchive
Large T antigen ma-jd-viral-21224
ORF1 ma-jd-viral-31901
ORF2 ma-jd-viral-67381
VP1 ma-jd-viral-14693
VP2 ma-jd-viral-40078

Squirrel monkey polyomavirus taxid:452475

Protein ModelArchive
Agno ma-jd-viral-53217
Capsid protein VP1 ma-jd-viral-14795
Large T antigen (LT) (LT-AG) (EC 3.6.4.-) ma-jd-viral-21125
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14795
Minor capsid protein ma-jd-viral-29772
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-31170
Small t antigen (ST) (ST-AG) ma-jd-viral-16650
Squirrel monkey agnoprotein (Agno) ma-jd-viral-53217

Sumatran orang-utan polyomavirus taxid:1604875

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14738
Large T antigen ma-jd-viral-21106
Minor capsid protein ma-jd-viral-29827
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29800
Small T antigen ma-jd-viral-16564

Tadarida brasiliensis polyomavirus 1 taxid:1588048

Protein ModelArchive
Large T antigen ma-jd-viral-21126
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48360
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48376
Small T antigen ma-jd-viral-16648
VP1 ma-jd-viral-14800

Tadarida brasiliensis polyomavirus 2 taxid:1588049

Protein ModelArchive
Large T antigen ma-jd-viral-21217
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48368
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48375
Small T antigen ma-jd-viral-16590
VP1 ma-jd-viral-14695

Trichodysplasia spinulosa-associated polyomavirus taxid:862909

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14780
Large T antigen ma-jd-viral-21187
Minor capsid protein ma-jd-viral-29754
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-29776
Small T antigen ma-jd-viral-16630

WU polyomavirus taxid:440266

Protein ModelArchive
Large T antigen ma-jd-viral-21122
Large T antigen (LT) (LT-AG) (EC 3.6.4.-) ma-jd-viral-21122
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14709
Major capsid protein VP1 (Major structural protein VP1) ma-jd-viral-14709
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-37804
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-38157
Small t antigen ma-jd-viral-16629
Small t antigen (ST) (ST-AG) ma-jd-viral-16629
VP2 ma-jd-viral-37804
VP3 ma-jd-viral-38157

Yellow baboon polyomavirus 1 taxid:1286213

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14789
Large T antigen ma-jd-viral-21193
Minor capsid protein ma-jd-viral-29758
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-31143
Small T antigen ma-jd-viral-16571

bat polyomavirus 2a taxid:2758131

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14703
Large T antigen ma-jd-viral-21190
Minor capsid protein ma-jd-viral-31180
Minor capsid protein ma-jd-viral-29790
Small t antigen ma-jd-viral-16621

bat polyomavirus 2b taxid:2758132

Protein ModelArchive
Capsid protein VP1 ma-jd-viral-14743
Large T antigen ma-jd-viral-21192
Minor capsid protein ma-jd-viral-31162
Minor capsid protein ma-jd-viral-29773
Small t antigen ma-jd-viral-16631

bat polyomavirus 4b taxid:2758138

Protein ModelArchive
Large T antigen ma-jd-viral-21105
Minor capsid protein VP2 (Minor structural protein VP2) ma-jd-viral-48398
Small t-antigen ma-jd-viral-16614
VP1 structural protein ma-jd-viral-14776