Viral attachment to host adhesion receptor (kw:KW-1233)
Adhesion receptors are attaching the virus in a reversible manner to target cells or organs. This adhesion is not mandatory for virus entry, and alone do not trigger entry. Nonetheless it enhances significantly infectivity by concentrating the virus in the vicinity of it's entry receptors, or bringing it to an organ in which are it's target cells.
In herpesviruses for example, gC makes the primary contact with the host cell surface, binding to heparan sulfate proteoglycans. Binding of gD to the entry receptors induces viral fusion to the host cell membrane and viral penetration .
Heldwein EE, Krummenacher C
Cell Mol Life Sci. 2008 Jun;65(11):1653-68
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)110 entries grouped by protein
4 entries
Capsid protein VP1 (Coat protein VP1)
13 entries
Depolymerase, capsule K1-specific (EC 4.-.-.-) (Dep_kpv71) (Gene product 52) (gp52) (Probable tail spike protein)
1 entry
Depolymerase, capsule K11-specific (Probable tail fiber protein)
1 entry
Depolymerase, capsule KN4-specific (Probable tail spike protein)
1 entry
Depolymerase, capsule K21-specific (Probable tail spike protein)
1 entry
Depolymerase, capsule KN5-specific (Probable tail fiber protein)
1 entry
Depolymerase, capsule K25-specific (Probable tail fiber protein)
1 entry
Probable tail spike protein (Depolymerase, capsule K35-specific)
1 entry
Depolymerase, capsule K1-specific (Probable tail fiber protein)
1 entry
Depolymerase, capsule K64-specific (Probable tail fiber protein)
1 entry
Depolymerase, capsule K30/K69-specific (Probable tail spike protein)
5 entries
Depolymerase 1, capsule K3-specific (Gene product 37) (gp37) (KP32gp37) (Probable tail spike protein)
5 entries
Depolymerase 2, capsule K5-specific (Gene product 38) (gp38) (K5 depolymerase) (Probable tail spike protein)
3 entries
Pre-neck appendage protein (Gene product 12) (gp12) (Late protein GP12) (NP1) (Protein p12)
1 entry
Long-tail fiber protein gp35 (Gene product 35) (gp35)
1 entry
Long-tail fiber protein gp36 (Gene product 36) (gp36)
1 entry
Long-tail fiber protein gp37 (Gene product 37) (gp37) (Receptor-recognizing protein)
1 entry
Tail fiber receptor-binding protein (Major tropism determinant protein)
8 entries
Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)
1 entry
Side tail fiber protein pb1 (STF-pb1) (EC 3.4.21.-) (LTF-pb1) (Tail protein pb1)
9 entries
Attachment protein G3P (Gene 3 protein) (G3P) (Minor coat protein)
11 entries
Envelope glycoprotein C
1 entry
Major surface glycoprotein G (Attachment glycoprotein G) (Membrane-bound glycoprotein) (mG)
3 entries
Maturation protein A2 (MP) (A2) (Assembly protein) (A protein)
1 entry
Non-contractile tail sheath (Gene product 65) (Gp65)
2 entries
Genome polyprotein
1 entry
Tail fiber protein S (Gene product 49) (gp49) (Gene product S) (gpS)
1 entry
Tail fiber protein S' (Gene product S') (gpS')
3 entries
Fiber protein 1
3 entries
Fiber protein 2
19 entries
Fiber protein (SPIKE) (Protein IV)
2 entries
Tail tubular protein A (TTPA) (Depolymerase) (EC 3.2.1.-) (Gene product 31) (gp31)
1 entry
Tail fiber assembly protein U (Gene product 50) (gp50) (Gene product U) (gpU)
1 entry