Viral genome excision

Most temperate phages encode an integrase for both integration and excision. Excision may require an accessory protein called excisionase or recombination directionality factor to promote excision Excision is the recombination event that leads to the release of a viral genome that was formerly integrated into the host DNA chromosome as a provirus. This release is usually induced upon changes in the host cell physiology (induction).

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NB. Aberrant excision may occur. Small pieces of bacterial DNA may become excised and packaged into the bacteriophage capsid together with the bacteriophage genome. This exchange of genetic information is called transduction .

Matching UniProtKB/Swiss-Prot entries

17 entries grouped by protein (browse by keywords)

1 entry

Recombination directionality factor (RDF) (Gene product 3) (gp3)

RDF_BPPHC
Streptomyces phage phiC31 (Bacteriophage phi-C31) reference strain

1 entry

Probable terminase, large subunit gp28 (EC 3.1.-.-) (Gene product 28) (gp28) (Gene product E) (gpE) (Pacase, large subunit) (Packaging protein E)

TERL_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

1 entry

Probable terminase, small subunit gp27 (Gene product 27) (gp27) (Gene product D) (gpD) (Pacase, small subunit) (Packaging protein D)

TERS_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

1 entry

Integrase (EC 2.7.7.-) (EC 3.1.-.-)

VINT_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

13 entries

Excisionase

Select_allDeselect_all
VXIS_BPAPS
Acyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1) reference strain

Probable excisionase (p40)

VXIS_BPHK6
Enterobacteria phage HK620 (Bacteriophage HK620) reference strain

Probable excisionase hkaC

VXIS_BPMD2
Mycobacterium phage D29 (Mycobacteriophage D29) reference strain

Excisionase (Gp36)

VXIS_BPML5
Mycobacterium phage L5 (Mycobacteriophage L5) reference strain

Excisionase (Gene product 36) (Gp36)

VXIS_BPP22
Salmonella phage P22 (Bacteriophage P22) reference strain
VXIS_BPSF5
Shigella phage SfV (Shigella flexneri bacteriophage V) (Bacteriophage SfV) reference strain
VXIS_BPSFV
Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI) reference strain

Probable excisionase hkaC

VXIS_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
VXIS_BP434
Enterobacteria phage 434 (Bacteriophage 434)
VXIS_BPHK0
Escherichia phage HK022 (Bacteriophage HK022)
VXIS_BPL54
Staphylococcus phage L54a (Bacteriophage L54a)
VXIS_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)
VXIS_BPPH8
Enterobacteria phage phi80 (Bacteriophage phi-80)