Luteoviridae

VIRION

Non-enveloped, spherical virion about 25-30 nm in diameter with T=3 icosahedral symmetry composed of 180 CP proteins.

GENOME

Monopartite, linear, ssRNA(+) genome of 5.3-5.7 kb. Poleroviruses and enamoviruses have a VPg bound at the 5' end. There is no poly(A) tail or tRNA-like structure at the 3' end.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The viral polymerase is expressed by a ribosomal frameshifting at the end of ORF1.

Depending on the genus, several proteins can be produced by Leaky scanning. Suppression of termination of the CP stop codon produces CP-RTD (CP extended), the capsid subunit essential for aphid transmission.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA ORF1 and ORF2 are translated to produce the RdRp fusion protein.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the 3' coterminal sgRNAs. Traduction of these sgRNAs yields the capsid, CP-RTD and movement proteins.
  7. Virus assembly.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Polerovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation .

Enamovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation

Barley yellow dwarf virus protein P6 acts as a suppressor of RNA silencing

Matching UniProtKB/Swiss-Prot entries

50 entries grouped by protein (browse by keywords)

All proteins are shown (view only 37 complete proteome entries)

12 entries

Major capsid protein (Coat protein) (CP)

Select_allDeselect_all
CAPSD_BYDV1
Barley yellow dwarf virus (isolate MAV-PS1) (BYDV) reference strain
CAPSD_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain
CAPSD_PEMVW
Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain
CAPSD_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
CAPSD_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain
CAPSD_BLRV
Bean leafroll virus (BLRV)
CAPSD_BYDVM
Barley yellow dwarf virus (isolate MAV) (BYDV)
CAPSD_BYDVN
Barley yellow dwarf virus (isolate NY-RPV) (BYDV)
CAPSD_BYDVR
Barley yellow dwarf virus (isolate P-PAV) (BYDV)
CAPSD_PLRV
Potato leafroll virus (PLrV)
CAPSD_PLRVR
Potato leafroll virus (strain Potato/Canada/Rowhani/1979) (PLrV)
CAPSD_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

5 entries

Minor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)

Select_allDeselect_all
MCAPS_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

Minor capsid protein (P74) (Readthrough protein) (RT protein)

MCAPS_PEMVW
Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain

Minor capsid protein P3-RTD (Readthrough protein) (RT protein)

MCAPS_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
MCAPS_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain
MCAPS_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

11 entries

Movement protein (MP) (17 kDa protein)

Select_allDeselect_all
MVP_BYDV1
Barley yellow dwarf virus (isolate MAV-PS1) (BYDV) reference strain
MVP_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain
MVP_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
MVP_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

Movement protein (MP) (20 kDa protein)

MVP_BLRV
Bean leafroll virus (BLRV)

Movement protein (MP) (16 kDa protein)

MVP_BWYVG
Beet western yellows virus (isolate GB1) (BWYV)

Movement protein (MP) (20 kDa protein)

MVP_BYDVN
Barley yellow dwarf virus (isolate NY-RPV) (BYDV)
MVP_BYDVR
Barley yellow dwarf virus (isolate P-PAV) (BYDV)
MVP_PLRV
Potato leafroll virus (PLrV)

Movement protein (MP) (17 kDa protein) (MP17)

MVP_PLRVR
Potato leafroll virus (strain Potato/Canada/Rowhani/1979) (PLrV)
MVP_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

1 entry

Protein ORF3a

ORF3A_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

1 entry

Uncharacterized protein ORF6

ORF6_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

1 entry

Uncharacterized protein ORF7

ORF7_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

4 entries

Suppressor of silencing P0 (28 kDa protein) (Protein ORF0)

Select_allDeselect_all
P0_PEMVW
Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain

Suppressor of silencing P0 (ORF0 protein)

P0_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
P0_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

Suppressor of silencing P0 (29 kDa protein) (Protein ORF0)

P0_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

4 entries

Protein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1)

Select_allDeselect_all
P1_PEMVW
Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain

Protein P1 (Genome-linked protein precursor) (ORF1 protein)

P1_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
P1_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

Protein P1 (66.2 kDa protein) (Genome-linked protein precursor) (Protein ORF1)

P1_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

2 entries

Uncharacterized protein P6 (ORF6 protein)

Select_allDeselect_all
P6_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
P6_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

2 entries

Replication-associated protein (Rap1)

Select_allDeselect_all
RAP1_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain
RAP1_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

7 entries

Putative RNA-directed RNA polymerase (EC 2.7.7.48)

Select_allDeselect_all
RDRP_BYDV1
Barley yellow dwarf virus (isolate MAV-PS1) (BYDV) reference strain
RDRP_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain
RDRP_PEMVW
Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain

Protein P1-P2

RDRP_PLRV1
Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain

Protein P1-P2

RDRP_TYYVF
Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

Protein P1-P2

RDRP_BYDVR
Barley yellow dwarf virus (isolate P-PAV) (BYDV)
RDRP_PLRVW
Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

Protein P1-P2