Lambdavirus

VIRION

Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).

GENOME

Linear, dsDNA genome of about 48 kb, containing about 70 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. The baseplate of the virion attaches to the entry receptor.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by theta replication.
  6. Replication of genomic DNA by rolling circle.
  7. Transcription and translation of late genes.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

108 entries grouped by protein (browse by keywords)

1 entry

Lipoprotein bor

BOR_LAMBD
Escherichia phage lambda (Bacteriophage lambda)

2 entries

Major capsid protein (Gene product 7) (Gene product E) (gpE) (Major head protein)

Select_allDeselect_all
CAPSD_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Major capsid protein (Gene product E) (gpE) (Major head protein)

CAPSD_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)

COMPL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

2 entries

Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)

Select_allDeselect_all
DECO_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
DECO_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

Head decoration protein (Head protein GPshp)

1 entry

DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)

DPOL_BPSP2
Bacillus phage SP02 (Bacteriophage SP02)

2 entries

Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36)

Select_allDeselect_all
DTX_CORBE
Corynephage beta
DTX_COROM
Corynephage omega

1 entry

Diphtheria toxin homolog CRM228

DTXH_CORBE
Corynephage beta

1 entry

Protein ea10

EA10_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Protein ea22

EA22_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Protein ea31

EA31_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Protein ea47

EA47_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Protein ea59

EA59_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Protein ea8.5

EA85_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

4 entries

SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)

Select_allDeselect_all
ENLYS_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Endolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

ENLYS_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)
ENLYS_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)
ENLYS_BPPA2
Enterobacteria phage PA-2 (Bacteriophage PA-2)

1 entry

Exonuclease (EC 3.1.11.3)

EXO_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

DNA-packaging protein FI

FI_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail fiber protein (stf) (Gene product 27) (gp27)

FIBER_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)

FII_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) (TAC)

G_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Host-nuclease inhibitor protein gam

GAM_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail assembly protein GT (Gene product 15) (gp15) (Gene product GT) (gpGT) (Minor tail protein GT)

GT_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Head completion protein (HCP) (Head-tail joining protein W) (gpW)

HCP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

2 entries

Antiholin

Select_allDeselect_all
HOLIN_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Antiholin (Lysis inhibitor S-107)

HOLIN_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Modification methylase Rho11sI (M.Rho11sI) (EC 2.1.1.37) (Bsu P11s) (Cytosine-specific methyltransferase Rho11sI)

MTBR_BPRH1
Bacillus phage rho11s (Bacteriophage rho-11s)

1 entry

Modification methylase SPRI (M.SPRI) (EC 2.1.1.37) (Cytosine-specific methyltransferase SPRI)

MTBS_BPSPR
Bacillus phage SPR (Bacteriophage SPR)

2 entries

Protein ninB

Select_allDeselect_all
NINB_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
NINB_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Protein ninD

NIND_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

4 entries

Protein ninE

Select_allDeselect_all
NINE_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Protein ninE (Nin60)

NINE_BP82
Enterobacteria phage 82 (Bacteriophage 82)
NINE_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)
NINE_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

3 entries

Protein ninF

Select_allDeselect_all
NINF_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
NINF_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)
NINF_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

3 entries

Protein ninG

Select_allDeselect_all
NING_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
NING_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)
NING_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

2 entries

Protein ninH

Select_allDeselect_all
NINH_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
NINH_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)

1 entry

Outer membrane porin protein LC

PORI_BPPA2
Enterobacteria phage PA-2 (Bacteriophage PA-2)

2 entries

Portal protein B (GpB) (Minor capsid protein B)

Select_allDeselect_all
PORTL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
PORTL_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Serine/threonine-protein phosphatase (EC 3.1.3.16)

PP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Restriction inhibitor protein ral (Antirestriction protein)

RAL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

2 entries

Regulatory protein cro

Select_allDeselect_all
RCRO_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
RCRO_BP434
Enterobacteria phage 434 (Bacteriophage 434)

Regulatory protein cro (Antirepressor)

1 entry

Antitermination protein N (Regulatory protein N) (PN)

REGN_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

3 entries

Antitermination protein Q

Select_allDeselect_all
REGQ_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
REGQ_BP82
Enterobacteria phage 82 (Bacteriophage 82)
REGQ_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)

2 entries

Protein rexA

Select_allDeselect_all
REXA_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
REXA_BP434
Enterobacteria phage 434 (Bacteriophage 434)

1 entry

Protein rexB

REXB_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Repressor protein cI

RPC1_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

2 entries

Regulatory protein CII

Select_allDeselect_all
RPC2_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Transcriptional activator II

RPC2_BP434
Enterobacteria phage 434 (Bacteriophage 434)

1 entry

Protease inhibitor III

RPC3_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Crossover junction endodeoxyribonuclease rusA (EC 3.1.22.4) (Holliday junction nuclease rusA) (Holliday junction resolvase)

RUSA_BP82
Enterobacteria phage 82 (Bacteriophage 82)

1 entry

Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)

SCAF_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Superinfection exclusion protein B

SIEB_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

2 entries

Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)

Select_allDeselect_all
SPAN1_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
SPAN1_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

2 entries

Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)

Select_allDeselect_all
SPAN2_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
SPAN2_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC 3.2.2.22) (Verocytotoxin 1 subunit A) (Verotoxin 1 subunit A) (rRNA N-glycosidase 1)

STXA_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)

1 entry

Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) (Verotoxin 1 subunit B)

STXB_BPH19
Enterobacteria phage H19B (Bacteriophage H19B)

2 entries

Terminase, large subunit (DNA-packaging protein A) (Large terminase protein) (gpA)

Select_allDeselect_all
TERL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
TERL_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

Terminase, large subunit (DNA-packaging protein) (DNA-packaging protein gp2) (Gene product 2) (gp2) (Large terminase protein)

2 entries

Terminase small subunit (EC 3.6.4.-) (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)

Select_allDeselect_all
TERS_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
TERS_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

Terminase, small subunit (Gp1)

1 entry

Tail fiber assembly protein

TFA_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail tip assembly protein I

TIPI_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tip attachment protein J (Central tail fiber) (Host specificity protein J)

TIPJ_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)

TIPK_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail tip protein L

TIPL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail tip protein M

TIPM_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H)

TMP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail sheath-stabilizing protein) (Tail-to-head joining protein) (THJP)

TTTP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)

TUBE_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Recombination protein bet

VBET_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5)

VG05_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

3 entries

Integrase (EC 2.7.7.-) (EC 3.1.-.-)

Select_allDeselect_all
VINT_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
VINT_BP434
Enterobacteria phage 434 (Bacteriophage 434)
VINT_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Protein kil

VKIL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Outer membrane protein lom (ORF 206A)

VLOM_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Protein ren

VREN_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Replication protein O

VRPO_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Replication protein P

VRPP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

3 entries

Excisionase

Select_allDeselect_all
VXIS_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain
VXIS_BP434
Enterobacteria phage 434 (Bacteriophage 434)
VXIS_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining protein)

W_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Uncharacterized nin region protein ORF290

Y290_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Putative uncharacterized protein ORF64

Y64_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

1 entry

Uncharacterized protein in rusA 5'region (ORF151)

YBCN_BP82
Enterobacteria phage 82 (Bacteriophage 82)

1 entry

Putative nuclease ybcO (EC 3.1.-.-)

YBCO_BP82
Enterobacteria phage 82 (Bacteriophage 82)

1 entry

Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region

YG78_BPP21
Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

1 entry

Uncharacterized protein in rusA 3'region (ORF45)

YLCG_BP82
Enterobacteria phage 82 (Bacteriophage 82)

1 entry

Uncharacterized 3.7 kDa protein in rusA 5'region (ORF33)

YLCH_BP82
Enterobacteria phage 82 (Bacteriophage 82)