Ceduovirus

VIRION

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Nonenveloped, head-tail structure. The prolate head is about 56 nm in length and 41 nm in width with a collar. The tail is cross-banded with a length of 86-111 nm and 8 nm in width. Tail has short fibers.

GENOME

Linear, dsDNA genome of about 22 kb with cos sites, containing about 40 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Viral exolysin degrades host cell wall locally.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by DNA strand displacement replication.
  6. Transcription and translation of late genes
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fibers assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.