Salasvirus (taxid:186846)
VIRION
|
Non-enveloped, head-tail structure. The prolate capsid is about 45 x 54 nm, with a T=3, Q=5 symmetry . The tail is non-contractile and has a collar with 12 appendages attached to the neck region that are important for host cell recognition and entry. The 55 capsid (head) fibers are not always present and may have been lost in some lab strains. They may enhance the attachment of the virions onto the host cell wall.
GENOME
Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes, with a terminal protein covalently attached at the 5' end.
GENE EXPRESSION
ENZYMES
- DNA dependent DNA polymerase [DNA pol]
- Protease (Peptidase G2) [Pre-neck appendage protein]
- Protein-primed terminal transferase [TP]
- Endolysin
REPLICATION
CYTOPLASMIC
- Adsorption: the phage attaches to target cell through its tail fibers.
- Ejection by short tail system: viral DNA is injected in host cell periplasm.
- Transcription and translation of early genes
- Replication of genomic DNA by strand displacement by the viral DNA polymerase, formation of viral genome concatemers.
- Transcription and translation of late genes
- Assembly of empty procapsids and viral genome packaging.
- Mature virions are released from the cell by lysis.
Kyung H. Choi, Marc C. Morais, Dwight L. Anderson, Michael G. Rossmann
Structure November 2006; 14: 1723-1727
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)58 entries grouped by protein
2 entries
Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
2 entries
Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
2 entries
Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
3 entries
DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
2 entries
Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase) (Protein p15)
2 entries
Pre-neck appendage protein (Gene product 12) (gp12) (NP1) (Protein p12)
2 entries
DNA replication protein 1 (Gene product 1) (gp1)
2 entries
Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13)
3 entries
Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
3 entries
Gene product 16.6 (gp16.6) (Protein p16.6)
3 entries
DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
3 entries
Gene product 16.8 (gp16.8) (Protein p16.8)
3 entries
Gene product 16.9 (gp16.9) (Protein p16.9)
3 entries
DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
2 entries
Gene product 5.5 (gp5.5) (Gene product 5B) (gp5B) (Protein p5.5)
2 entries
Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14)
2 entries
Histone-like protein p6 (Double-stranded DNA-binding protein p6) (Gene product 6) (gp6) (Nucleoid-associated protein p6) (Protein p6)
2 entries
Protein p56
2 entries
DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
2 entries
Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) (gp19) (Head-to-tail connector) (Probable portal protein) (Protein p10) (Upper collar protein)
2 entries
Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) (Scaffold protein)
2 entries
Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
2 entries
DNA terminal protein (Gene product 3) (gp3) (Protein p3)
2 entries
Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
2 entries
Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)
1 entry