Syncytium formation induced by viral infection

Syncytia is formed by fusion of an infected cells with neighboring cells leading to the formation of multi-nucleate enlarged cells. This event is induced by surface expression of viral fusion protein that are fusogenic directly at the host cell membrane.
Syncytia canonly happen with viruses able to directly fuse at the cellular surface without the need of endocytosis.

Matching UniProtKB/Swiss-Prot entries

10 entries grouped by protein (browse by keywords)

Only complete proteome entries are shown (view all 21 entries)

3 entries

Fusion glycoprotein F0 (Protein F)

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FUS_BRSVA
Bovine respiratory syncytial virus (strain A51908) (BRS) reference strain

Fusion glycoprotein F0

FUS_HRSVA
Human respiratory syncytial virus A (strain A2) reference strain
FUS_HRSVB
Human respiratory syncytial virus B (strain B1) reference strain

7 entries

Envelope glycoprotein K (Syncytial protein)

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GK_EHV1B
Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain
GK_GAHVM
Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain

Envelope glycoprotein K

GK_HHV11
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain
GK_HHV2H
Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain
GK_PSHV1
Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) reference strain
GK_VZVD
Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain
GK_VZVO
Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)