Luteovirus

VIRION

Non-enveloped, spherical virion about 25-30 nm in diameter with T=3 icosahedral symmetry composed of 180 CP proteins.

GENOME

Monopartite, linear, ssRNA(+) genome of 5.3-5.7 kb in size. Poleroviruses and enamoviruses have a VPg bound at the 5' end. There is no poly(A) tail or tRNA-like structure at the 3' end.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The only proteins translated directly from genomic RNA are the polymerase (ORF2), which is expressed as a fusion protein by a -1 ribosomal frameshifting at the end of ORF1, and ORF1 protein. All other ORFs are translated from subgenomic RNAs (sgRNAs).

The movement protein and P3a are expressed by leaky scanning of the subgenomic mRNA. Suppression of termination of the CP stop codon produces CP-RTD (CP extended), the capsid subunit essential for aphid transmission.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA ORF1 and ORF2 are translated to produce the RdRp fusion protein.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the 3' coterminal sgRNAs. Traduction of these sgRNAs yields the capsid, CP-RTD and movement proteins.
  7. Virus assembly.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Barley yellow dwarf virus protein P6 acts as a suppressor of RNA silencing

Matching UniProtKB/Swiss-Prot entries

17 entries grouped by protein (browse by keywords)

All proteins are shown (view only 9 complete proteome entries)

6 entries

Major capsid protein (Coat protein) (CP)

Select_allDeselect_all
CAPSD_BYDV1
Barley yellow dwarf virus (isolate MAV-PS1) (BYDV) reference strain
CAPSD_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain
CAPSD_BLRV
Bean leafroll virus (BLRV)
CAPSD_BYDVM
Barley yellow dwarf virus (isolate MAV) (BYDV)
CAPSD_BYDVN
Barley yellow dwarf virus (isolate NY-RPV) (BYDV)
CAPSD_BYDVR
Barley yellow dwarf virus (isolate P-PAV) (BYDV)

1 entry

Minor capsid protein (P74) (Readthrough protein) (RT protein)

MCAPS_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

5 entries

Movement protein (MP) (17 kDa protein)

Select_allDeselect_all
MVP_BYDV1
Barley yellow dwarf virus (isolate MAV-PS1) (BYDV) reference strain
MVP_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain
MVP_BLRV
Bean leafroll virus (BLRV)

Movement protein (MP) (16 kDa protein)

MVP_BYDVN
Barley yellow dwarf virus (isolate NY-RPV) (BYDV)
MVP_BYDVR
Barley yellow dwarf virus (isolate P-PAV) (BYDV)

1 entry

Uncharacterized protein ORF6

ORF6_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

1 entry

Uncharacterized protein ORF7

ORF7_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

3 entries

Putative RNA-directed RNA polymerase (EC 2.7.7.48)

Select_allDeselect_all
RDRP_BYDV1
Barley yellow dwarf virus (isolate MAV-PS1) (BYDV) reference strain
RDRP_BYDVP
Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain
RDRP_BYDVR
Barley yellow dwarf virus (isolate P-PAV) (BYDV)