Chuviridae (taxid:2501952)

VIRION

Unknown, discovered using viral metagenomics. Presumably non enveloped.

GENOME

Segmented negative-stranded RNA linear genome, RNA1 segment is about 6.5kb, RNA2 segment about 1.3kb
Encodes for two proteins.

GENE EXPRESSION

Viral RNA-dependent RNA polymerase (L) binds to a promoter on each segment and transcribes a messenger RNA. Genomic RNA is possibly encapsidated by N protein.

ENZYMES

• RNA-dependent RNA polymerase L
• Mononega-type capping
  • RNA TPase, GTase, N7 Mtase, 2'O Mtase L

REPLICATION

NUCLEAR or CYTOPLASMIC

1. Virus invades host cells by unknown mechanism: genomic genome is released in cytoplasm.
2. Transcription
3. Replication
4. Unknown mechanism of propagation.