Culicidavirus (taxid:2842620)

VIRION

Unknown, discovered using viral metagenomics. Presumably enveloped.

GENOME

Negative-stranded RNA linear genome, about 12 kb in size. Encodes for four proteins.

GENE EXPRESSION

Viral RNA-dependent RNA polymerase (L) binds to a promoter on each segment and transcribes a messenger RNA. Genomic RNA is possibly encapsidated by N protein.

ENZYMES

• RNA-dependent RNA polymerase [L]
• Mononega-type capping
  • RNA TPase, GTase, N7 Mtase, 2'O Mtase [L]

REPLICATION

NUCLEAR or CYTOPLASMIC

1. Virus invades host cells by unknown mechanism: genomic genome is released in cytoplasm.
2. Transcription
3. Replication
4. Unknown mechanism of propagation.