Natareviridae

VIRION

Unknown, discovered using viral metagenomics. Presumably enveloped.

GENOME

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Monopartite Negative-stranded RNA linear genome about 13 kb
Encodes for four proteins.

GENE EXPRESSION

Viral RNA-dependent RNA polymerase (L) binds to a promoter on each segment and transcribes a messenger RNA. Genomic RNA is possibly encapsidated by N protein.

REPLICATION

NUCLEAR or CYTOPLASMIC?

  1. Virus invades host cells by unknown mechanism: genomic segments are released in cytoplasm.
  2. Transcription
  3. Replication
  4. Unknown mechanism of propagation.