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ViralZone resources

Betacoronavirus fact sheet image Genome and expressionimage Variants image
Coronavirus life cycle image Proteome image Interactome image
COVID-19 and treatment image Vaccines image Antiviral drugs image


External resources:


COVID-19 UniProt resource

image 		Cellosaurus
Cell culture for SARS-Cov-2image 		Nextstrain

Genomic epidemiology of SARSCoV2 image

SIB SARS-CoV-2 resources image 		NCBI SARS-CoV-2
image 		Elixir SARS-CoV-2
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PDB structures
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Worldmeter of COVID-19 infections/deaths
image 		Medical data on COVID-19
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Coronaviruses 101:
Focus on Molecular Virology
by Britt Glaunsinger, University of California image
DB LINKS Nucleotide DB: NCBI
Protein DB: UniProtKB
Virus DB:
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TAXONOMY Group IV: ssRNA positive-strand viruses
Order:Nidovirales
Family:Coronaviridae
Subfamily: Coronavirinae
Genus: Betacoronavirus
ETYMOLOGY Coronavirus: from latin corona (crown), referring to the shape of proteins around the virion
SPECIES
REFERENCE STRAINS SARS-CoV-2
Sequence | UCSC genome | Proteome

Host

NATURAL HOSTS Human. Occasional: Mink, great apes (gorrilla,.), Feline (cats,lion, tigers,.), dogs, bats, pangolin.
TROPISM Primary site of infection: epithelial cells of respiratory or enteric tracts. secondary: Central Nervous System, kidney, heart tissues?
INTERACTIONS Cell receptors:

SARS-CoV-2: ACE2

Ecology and disease

GEOGRAPHY Worldwide, Emerged in China.
ASSOCIATED DISEASES COVID-19: Mainly respiratory diseases (pneumonia), with cardiac complications.
TRANSMISSION Respiratory droplets, fomites.
VACCINE
ANTIVIRAL DRUGS Remdesivir (Experimental, viral polymerase inhibitor)