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RetroMA-fold

RetroMA-fold proteins form a matrix under the virion membrane

Origin

The retroviral matrix protein exhibits striking structural and functional similarity to the bacterial integron recombinase, suggesting that it was likely exapted from this ancestral system .

Topology

Retroviral matrix protein is composed of a core structure of 4 alpha helixes arranged in two layers.

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HIV-1 MA 4ZV5