Lambdavirus (taxid:186765)
VIRION
Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).
GENOME
Linear, dsDNA genome of about 48 kb, containing about 70 genes.
GENE EXPRESSION
ENZYMES
- Terminase [TermS, TermL]
- Integrase
- Exonuclease [P03697]
- Serine protease (Peptidase S49) [P03711]
- Endolysin [P03706]
- Phosphatase [P03772]
REPLICATION
CYTOPLASMIC
- Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
- The baseplate of the virion attaches to the entry receptor.
- Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
- Transcription and translation of early genes.
- Replication of genomic DNA by theta replication.
- Replication of genomic DNA by rolling circle.
- Transcription and translation of late genes.
- Assembly of empty procapsids and viral genome packaging.
- Mature virions are released from the cell by lysis.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)108 entries grouped by protein
1 entry
Lipoprotein bor
2 entries
Major capsid protein (Gene product 7) (Gene product E) (gpE) (Major head protein)
1 entry
Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)
2 entries
Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)
1 entry
DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)
2 entries
Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36)
1 entry
Diphtheria toxin homolog CRM228
1 entry
Protein ea10
1 entry
Protein ea22
1 entry
Protein ea31
1 entry
Protein ea47
1 entry
Protein ea59
1 entry
Protein ea8.5
4 entries
SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)
1 entry
Exonuclease (EC 3.1.11.3)
1 entry
DNA-packaging protein FI
1 entry
Tail fiber protein (stf) (Gene product 27) (gp27)
1 entry
Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)
1 entry
Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) (TAC)
1 entry
Host-nuclease inhibitor protein gam
1 entry
Tail assembly protein GT (Gene product 15) (gp15) (Gene product GT) (gpGT) (Minor tail protein GT)
1 entry
Head completion protein (HCP) (Head-tail joining protein W) (gpW)
2 entries
Antiholin
1 entry
Orphan methyltransferase M.Rho11sI (M.Rho11sI) (EC 2.1.1.37) (Bsu P11s) (Cytosine-specific methyltransferase Rho11sI) (Modification methylase Rho11sI)
2 entries
Protein ninB
1 entry
Protein ninD
4 entries
Protein ninE
3 entries
Protein ninF
3 entries
Protein ninG
2 entries
Protein ninH
1 entry
Outer membrane porin protein LC
2 entries
Portal protein B (GpB) (Minor capsid protein B)
1 entry
Serine/threonine-protein phosphatase (EC 3.1.3.16)
1 entry
Restriction inhibitor protein ral (Antirestriction protein)
2 entries
Regulatory protein cro
1 entry
Antitermination protein N (Regulatory protein N) (PN)
3 entries
Antitermination protein Q
2 entries
Protein rexA
1 entry
Protein rexB
1 entry
Repressor protein cI
2 entries
Regulatory protein CII
1 entry
Protease inhibitor III
1 entry
Crossover junction endodeoxyribonuclease rusA (EC 3.1.21.10) (Holliday junction nuclease rusA) (Holliday junction resolvase)
1 entry
Staphylokinase (Neutral proteinase) (Protease III) (SakSTAR)
1 entry
Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)
1 entry
Superinfection exclusion protein B
2 entries
Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
2 entries
Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
1 entry
Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC 3.2.2.22) (Verocytotoxin 1 subunit A) (Verotoxin 1 subunit A) (rRNA N-glycosidase 1)
1 entry
Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) (Verotoxin 1 subunit B)
2 entries
Terminase, large subunit (DNA-packaging protein A) (Large terminase protein) (gpA)
2 entries
Terminase small subunit (EC 3.6.4.-) (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)
1 entry
Tail fiber assembly protein
1 entry
Tail tip assembly protein I
1 entry
Tip attachment protein J (Central tail fiber) (Host specificity protein J) (gpJ protein)
1 entry
Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)
1 entry
Tail tip protein L
1 entry
Tail tip protein M
1 entry
Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H)
1 entry
Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail sheath-stabilizing protein) (Tail-to-head joining protein) (THJP)
1 entry
Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)
1 entry
Recombination protein bet
1 entry
Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5)
3 entries
Integrase (EC 2.7.7.-) (EC 3.1.-.-)
1 entry
Protein kil
1 entry
Outer membrane protein lom (ORF 206A)
1 entry
Protein ren
1 entry
Replication protein O
1 entry
Helicase loader (Lambda P helicase loader) (Replication protein P)
3 entries
Excisionase
1 entry
Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining protein)
1 entry
Uncharacterized nin region protein ORF290
1 entry
Putative uncharacterized protein ORF64
1 entry
Uncharacterized protein in rusA 5'region (ORF151)
1 entry
Putative nuclease ybcO (EC 3.1.-.-)
1 entry
Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region
1 entry
Uncharacterized protein in rusA 3'region (ORF45)
1 entry