Teseptimavirus (taxid:110456)
VIRION
Non-enveloped, head-tail structure. Head is about 60 nm in diameter. The tail is non-contractile, has 6 short subterminal fibers. The capsid is icosahedral with a T=7 symmetry.
GENOME
Linear, dsDNA genome of about 40-42 kb encoding for about 55 genes.
GENE EXPRESSION
ENZYMES
- T7 RNA polymerase [1]
- DNA-directed DNA polymerase [5]
- Primase [4]
- Terminase [19, 18]
- DNA ligase [1.3]
- Kinase [0.7]
- Endonuclease [3]
- Exonuclease [6]
- Nucleotide kinase [1.7]
- Endolysin [3.5]
- Peptidoglycan transglycosylase [gp16]
REPLICATION
CYTOPLASMIC
- The phage attaches to target cell adhesion receptors through its tail fibers.
- Ejection by short tail system: viral DNA is injected in host cell periplasm.
- Transcription of class I genes by host RNA polymerase before the viral genome completely exits out of capsid.
- Transcription of class II genes by T7 RNA polymerase.
- Bacterial genome degradation
- Replication of genomic DNA by T7 DNA polymerase, formation of viral genome concatemers.
- Transcription of class III genes by T7 RNA polymerase.
- Assembly of empty procapsids and viral genome packaging.
- Mature virions are released from the cell by lysis.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)57 entries grouped by protein
1 entry
Major capsid protein (Gene product 10A) (Gp10A) (Major head protein)
1 entry
Minor capsid protein (Gene product 10B) (Gp10B) (Minor head protein)
1 entry
DNA ligase (EC 6.5.1.1) (DNA ligase gp1.3) (Gene product 1.3) (Gp1.3)
1 entry
DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)
1 entry
Endonuclease I (EC 3.1.21.2) (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)
1 entry
Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (T7 endolysin)
1 entry
Peptidoglycan transglycosylase gp16 (EC 4.2.2.n1) (Internal core protein gp16)
1 entry
Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3)
1 entry
Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)
1 entry
Gene 0.4 protein (Gene product 0.4) (Gp0.4)
1 entry
Inhibitor of dGTPase (Gene product 1.2) (Gp1.2) (Inhibitor of dGTPase gp1.2)
1 entry
Probable scaffold protein gp13 (Gene product 13) (Gp13)
1 entry
Internal virion protein gp14 (Gene product 14) (Gp14)
1 entry
Internal virion protein gp15 (Gene product 15) (Gp15)
1 entry
Probable RecBCD inhibitor gp5.9 (Gene product 5.9) (Gp5.9)
1 entry
Protein 6.7 (Gene product 6.7) (Gp6.7)
1 entry
Protein 7.3 (Gene product 7.3) (Gp7.3)
1 entry
DNA helicase/primase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)
1 entry
Holin (Gene product 17.5) (Gp17.5)
1 entry
Inhibitor of toxin/antitoxin system (Gene product 4.5) (Gp4.5)
1 entry
Nucleotide kinase gp1.7 (Gene product 1.7) (Gp1.7) (EC 2.7.4.-)
1 entry
Protein Ocr (Gene product 0.3) (Gp0.3) (Overcome classical restriction) (Ocr)
1 entry
Protein kinase 0.7 (EC 2.7.11.1) (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)
1 entry
Portal protein (Gene product 8) (Gp8) (Head-to-tail connector)
1 entry
T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)
1 entry
Capsid assembly scaffolding protein (Gene product 9) (Gp9) (Head morphogenesis protein) (Scaffold protein)
1 entry
Protein suppressor of silencing (Gene product 5.5)
1 entry
Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)
1 entry
Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)
1 entry
Single-stranded DNA-binding protein (SSB protein) (2.5 protein) (Gene product 2.5) (gp2.5)
1 entry
Terminase, large subunit (DNA-packaging protein) (Gene product 19) (Gp19)
1 entry
Terminase, small subunit gp18 (DNA-packaging protein A) (Gene product 18) (Gp18)
1 entry
Tail tubular protein gp11 (Gene product 11) (Gp11)
1 entry
Tail tubular protein gp12 (Gene product 12) (Gp12)
1 entry
Fusion protein 5.5/5.7
1 entry
Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)
1 entry
Protein 0.5 (Gene product 0.5) (Gp0.5)
1 entry
Protein 0.6B
1 entry
Uncharacterized protein 1.1 (Gene product 1.1) (Gp1.1)
1 entry
Protein 1.4 (Gene product 1.4) (Gp1.4)
1 entry
Protein 1.5 (Gene product 1.5) (Gp1.5)
1 entry
Protein 1.6 (Gene product 1.6) (Gp1.6)
1 entry
Protein 1.8 (Gene product 1.8) (Gp1.8)
1 entry
Protein 19.2 (Gene product 19.2) (Gp19.2)
1 entry
Protein 19.3 (Gene product 19.3) (Gp19.2)
1 entry
Protein 19.5 (Gene product 19.5) (Gp19.5)
1 entry
Protein 2.8 (Gene product 2.8) (Gp2.8)
1 entry
Protein 3.8 (Gene product 3.8) (Gp3.8)
1 entry
Protein 4.1 (Gene product 4.1) (Gp4.1)
1 entry
Protein 4.2 (Gene product 4.2) (Gp4.2)
1 entry
Protein 4.3 (Gene product 4.3) (Gp4.3)
1 entry
Protein 4.7 (Gene product 4.7) (Gp4.7)
1 entry
Protein 5.3 (Gene product 5.3) (Gp5.3)
1 entry
Protein 6.3 (Gene product 6.3) (Gp6.3)
1 entry
Protein 6.5 (Gene product 6.5) (Gp6.5)
1 entry
Protein 7 (Gene product 7) (Gp7)
1 entry