Lederbergvirus (taxid:186794)

VIRION

Non-enveloped, head-tail structure. The capsid is about 60-65 nm in diameter, with a T=7 laevo icosahedral symmetry . The tail is non-contractile, has 6 prominent tail spikes.

GENOME

Linear, dsDNA genome of about 41 kb encoding for at least 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

Adsorption: the phage attaches to the target cell through its tail fibers.
Ejection of the viral DNA into host cell cytoplasm.
Transcription and translation of early genes.
Replication of genomic DNA. Transcription and translation of late genes.
Assembly of an empty procapsid and packaging of the genome.
Viral tail fibers assembly and viral tail assembly.
Mature virions are released from the cell by lysis.

DB LINKS

TAXONOMY Group I: dsDNA viruses

Realm:	Duplodnaviria
Kingdom:	Heunggongvirae
Phylum:	Uroviricota
Class:	Caudoviricetes
Order:	Unassigned
Family:	Unassigned
Genus:	P22virus

VIRUS

Salmonella virus P22
Salmonella virus BTP1
Salmonella virus HK620
Salmonella virus ST64T
Shigella virus Sf6

REFERENCE STRAINS Enterobacteria phage P22 virus
Sequence | Genome assembly | Proteome

Host

NATURAL HOSTS Bacteria

Ecology and disease

GEOGRAPHY Worldwide

TRANSMISSION Passive diffusion through medium

ANTIVIRAL DRUGS

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

76 entries grouped by protein

reorder by strain

1 entry

Anti-RecBCD protein 1 (Protein abc1)

1 entry

Anti-RecBCD protein 2 (Protein abc2)

1 entry

Major capsid protein (Gene product 5) (gp5) (Major head protein)

1 entry

Decoration protein (Dec)

1 entry

Ead protein

1 entry

Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

1 entry

Essential recombination function protein

1 entry

Head-to-tail adapter protein gp4 (Gene product 4) (Gp4) (Internal virion protein gp4) (Peptidoglycan hydrolase gp4) (Tail adapter protein gp4)

2 entries

Tail spike protein (TSP) (Endo-1,3-alpha-L-rhamnosidase) (EC 3.2.1.-) (Endorhamnosidase)

FIBER_BPP22

Salmonella phage P22 (Bacteriophage P22) reference strain

Tail spike protein (TSP) (Endo-1,3-alpha-L-rhamnosidase) (EC 3.2.1.-) (Endorhamnosidase) (Gene product 9) (gp9)

1CLW; 1LKT; 1QA1; 1QA2; 1QA3; 1QQ1; 1QRB; 1QRC; 1TSP; 1TYU; 1TYV; 1TYW; 1TYX; 2VFM; 2VFN; 2VFO; 2VFP; 2VFQ; 2VKY; 2VNL; 2XC1; 3TH0; 5GAI; 8EAN; 8EB7; 8TVR; 8U10; 8U11; 8U1O

FIBER_BPSFV

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI)

2VBE; 2VBK; 2VBM; 4URR; 7SG7; 7UKJ

1 entry

Internal virion protein gp16 (Ejection protein gp16) (E protein gp16)

1 entry

Internal virion protein gp20 (Ejection protein gp20) (E protein gp20)

1 entry

Internal virion protein gp7 (Ejection protein gp7) (E protein gp7)

1 entry

Bactoprenol-linked glucose translocase

1 entry

Bactoprenol glucosyl transferase (EC 2.4.1.-)

1 entry

Antiholin (Lysis inhibitor 13-108)

1 entry

Tail hub protein gp10

3 entries

Tail needle protein gp26 (Head completion protein) (Packaged DNA stabilization protein) (Tail accessory factor gp26)

NEEDL_BPHK6

Enterobacteria phage HK620 (Bacteriophage HK620) reference strain

5BU5; 5BU8; 5BVZ

NEEDL_BPP22

Salmonella phage P22 (Bacteriophage P22) reference strain

2POH; 3C9I; 4LIN; 4ZKP; 4ZKU; 4ZXQ; 8EAP

NEEDL_BPSFV

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI) reference strain

Tail needle protein (Head completion protein) (Packaged DNA stabilization protein) (Tail accessory factor gp9)

3RWN

1 entry

Protein ninB

1 entry

Protein ninD

1 entry

Protein ninE

1 entry

Protein ninF

1 entry

Protein ninG

1 entry

Protein ninH

1 entry

Putative protein ninX

1 entry

Putative protein ninY

1 entry

O-acetyl transferase (EC 2.3.1.-) (O-antigen acetylase)

1 entry

Portal protein (Gene product 1) (Gp1) (Head-to-tail connector)

1 entry

Restriction inhibitor protein ral (Antirestriction protein)

1 entry

Antirepressor protein ant

1 entry

Transcriptional repressor arc

1 entry

Regulatory protein cro (Antirepressor)

1 entry

Probable regulatory protein N

1 entry

Antitermination protein Q

1 entry

Regulatory protein mnt

1 entry

Transcriptional activator protein C1

1 entry

Repressor protein C2

1 entry

Regulatory protein C3 (CIII)

1 entry

Scaffolding protein (Gene product 8) (gp8)

1 entry

Superinfection exclusion protein A

1 entry

Superinfection exclusion protein B

1 entry

Spanin, inner membrane subunit (i-spanin) (Gene product 15) (Gp15) (Lysis protein Rz)

1 entry

Probable spanin, outer lipoprotein subunit (o-spanin) (Rz1 protein)

1 entry

Terminase, large subunit (DNA-packaging protein gp2)

2 entries

Terminase, small subunit (DNA-packaging protein gp3)

TERS_BPP22

Salmonella phage P22 (Bacteriophage P22) reference strain

3P9A

TERS_BPLP7

Enterobacteria phage LP7 (Bacteriophage LP7)

1 entry

Accessory recombination function protein

1 entry

Eaa protein

1 entry

Eac protein

1 entry

Eae protein

1 entry

Eaf protein

1 entry

Eag protein

1 entry

Eai protein

2 entries

DNA transfer protein gp7

VG07_BPHK6

Enterobacteria phage HK620 (Bacteriophage HK620) reference strain

VG07_BPST6

Salmonella phage ST64T (Bacteriophage ST64T) reference strain

1 entry

Replicative DNA helicase (EC 5.6.2.3) (DNA 5'-3' helicase gp12) (Replication protein gp12)

1 entry

Protein gp14

1 entry

Superinfection exclusion protein (Protein gp17)

1 entry

DNA replication protein gp18

2 entries

Integrase (EC 2.7.7.-) (EC 3.1.-.-)

VINT_BPP22

Salmonella phage P22 (Bacteriophage P22) reference strain

VINT_BPSFV

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI)

1 entry

Protein kil

3 entries

Probable excisionase hkaC

VXIS_BPHK6

Enterobacteria phage HK620 (Bacteriophage HK620) reference strain

VXIS_BPP22

Salmonella phage P22 (Bacteriophage P22) reference strain

Excisionase

VXIS_BPSFV

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI) reference strain

1 entry

Uncharacterized 22.8 kDa protein in gp15-gp3 intergenic region (ORF201)

1 entry

Uncharacterized 55.3 kDa protein in gtrB 5'region (ORF485)

1 entry

Uncharacterized 6.4 kDa protein in sieA-mnt intergenic region (ORF59A)

1 entry

Uncharacterized 6.6 kDa protein in eae-abc2 intergenic region (ORF56)

1 entry

Uncharacterized 7.7 kDa protein in gp5-gp4 intergenic region (ORF 109) (ORF69)

1 entry

Uncharacterized 7.8 kDa protein in ral-gp17 intergenic region (ORF67)

1 entry

Uncharacterized 8.6 kDa protein in ral-gp17 intergenic region (ORF78)

1 entry

Uncharacterized 9.0 kDa protein in gp15-gp3 intergenic region (ORF80)

1 entry

Lederbergvirus (taxid:186794)

VIRION

GENOME

GENE EXPRESSION

REPLICATION

Host

Ecology and disease

Matching UniProtKB/Swiss-Prot entries

Anti-RecBCD protein 1 (Protein abc1)

Anti-RecBCD protein 2 (Protein abc2)

Major capsid protein (Gene product 5) (gp5) (Major head protein)

Decoration protein (Dec)

Ead protein

Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Essential recombination function protein

Head-to-tail adapter protein gp4 (Gene product 4) (Gp4) (Internal virion protein gp4) (Peptidoglycan hydrolase gp4) (Tail adapter protein gp4)

Tail spike protein (TSP) (Endo-1,3-alpha-L-rhamnosidase) (EC 3.2.1.-) (Endorhamnosidase)

Internal virion protein gp16 (Ejection protein gp16) (E protein gp16)

Internal virion protein gp20 (Ejection protein gp20) (E protein gp20)

Internal virion protein gp7 (Ejection protein gp7) (E protein gp7)

Bactoprenol-linked glucose translocase

Bactoprenol glucosyl transferase (EC 2.4.1.-)

Antiholin (Lysis inhibitor 13-108)

Tail hub protein gp10

Tail needle protein gp26 (Head completion protein) (Packaged DNA stabilization protein) (Tail accessory factor gp26)

Protein ninB

Protein ninD

Protein ninE

Protein ninF

Protein ninG

Protein ninH

Putative protein ninX

Putative protein ninY

O-acetyl transferase (EC 2.3.1.-) (O-antigen acetylase)

Portal protein (Gene product 1) (Gp1) (Head-to-tail connector)

Restriction inhibitor protein ral (Antirestriction protein)

Antirepressor protein ant

Transcriptional repressor arc

Regulatory protein cro (Antirepressor)

Probable regulatory protein N

Antitermination protein Q

Regulatory protein mnt

Transcriptional activator protein C1

Repressor protein C2

Regulatory protein C3 (CIII)

Scaffolding protein (Gene product 8) (gp8)

Superinfection exclusion protein A

Superinfection exclusion protein B

Spanin, inner membrane subunit (i-spanin) (Gene product 15) (Gp15) (Lysis protein Rz)

Probable spanin, outer lipoprotein subunit (o-spanin) (Rz1 protein)

Terminase, large subunit (DNA-packaging protein gp2)

Terminase, small subunit (DNA-packaging protein gp3)

Accessory recombination function protein

Eaa protein

Eac protein

Eae protein

Eaf protein

Eag protein

Eai protein

DNA transfer protein gp7

Replicative DNA helicase (EC 5.6.2.3) (DNA 5'-3' helicase gp12) (Replication protein gp12)

Protein gp14

Superinfection exclusion protein (Protein gp17)

DNA replication protein gp18

Integrase (EC 2.7.7.-) (EC 3.1.-.-)

Protein kil

Probable excisionase hkaC

Uncharacterized 22.8 kDa protein in gp15-gp3 intergenic region (ORF201)

Uncharacterized 55.3 kDa protein in gtrB 5'region (ORF485)

Uncharacterized 6.4 kDa protein in sieA-mnt intergenic region (ORF59A)

Uncharacterized 6.6 kDa protein in eae-abc2 intergenic region (ORF56)

Uncharacterized 7.7 kDa protein in gp5-gp4 intergenic region (ORF 109) (ORF69)

Uncharacterized 7.8 kDa protein in ral-gp17 intergenic region (ORF67)

Uncharacterized 8.6 kDa protein in ral-gp17 intergenic region (ORF78)

Uncharacterized 9.0 kDa protein in gp15-gp3 intergenic region (ORF80)

Uncharacterized 5.8 kDa protein (ORF48)