Viral attachment to host entry receptor (kw:KW-1234)
Entry receptors trigger virus entry by endocytosis/pinocytosis or by inducing fusion/penetration. The consequences of this binding are irreversible. They have often be named "co-receptors". Entry receptors are often difficult to access for the virion, which circumvents this problem by binding first to adhesion receptors, which increases the probability of binding to the entry receptor.
In herpesviruses for example, gC makes the primary contact with the host cell surface, binding to heparan sulfate proteoglycans. Binding of gD to the entry receptors induces viral fusion to the host cell membrane and viral penetration
.
In bacterial viruses, attachment to the entry receptor is often referred to as irreversible adsorption, based on experimental observations .
Rakhuba DV, Kolomiets EI, Dey ES, Novik GI
Pol J Microbiol. 2010;59(3):145-55
Heldwein EE, Krummenacher C
Cell Mol Life Sci. 2008 Jun;65(11):1653-68
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)141 entries grouped by strain
4 entries
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5) reference strain
4 entries
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) reference strain
2 entries
Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus) reference strain
1 entry
Avian leukosis virus subgroup A (isolate RSA) (ALV-A RSA) reference strain
1 entry
Bacillus phage SPP1 (Bacteriophage SPP1) reference strain
1 entry
Bhanja virus (BHAV) reference strain
1 entry
Bovine respiratory syncytial virus (strain A51908) (BRS) reference strain
1 entry
Chikungunya virus (strain S27-African prototype) (CHIKV) reference strain
1 entry
Enterobacteria phage I2-2 (Bacteriophage I2-2) reference strain
1 entry
Enterobacteria phage M13 (Bacteriophage M13) reference strain
1 entry
Enterobacteria phage T4 (Bacteriophage T4) reference strain
1 entry
Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain
1 entry
Escherichia phage If1 (Bacteriophage If1) reference strain
1 entry
Escherichia phage P2 (Bacteriophage P2) reference strain
1 entry
Escherichia phage T5 (Enterobacteria phage T5) reference strain
1 entry
Escherichia phage lambda (Bacteriophage lambda) reference strain
1 entry
Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain
1 entry
Guinea pig cytomegalovirus (strain 22122) (GPCMV) reference strain
1 entry
Hepatitis C virus genotype 1a (isolate H77) (HCV) reference strain
1 entry
Hepatitis E virus genotype 1 (isolate Human/China/HeBei/1987) (HEV) reference strain
1 entry
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain
1 entry
Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain
1 entry
Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic virus) reference strain
1 entry
Human respiratory syncytial virus B (strain B1) reference strain
1 entry
Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1) reference strain
1 entry
Murine pneumonia virus (strain 15) (MPV) reference strain
1 entry
Pseudomonas phage Pf1 (Bacteriophage Pf1) reference strain
1 entry
Pseudomonas phage Pf3 (Bacteriophage Pf3) reference strain
1 entry
Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) reference strain
1 entry
Rift valley fever virus (strain ZH-548 M12) (RVFV) reference strain
1 entry
SFTS phlebovirus (isolate SFTSV/Human/China/HB29/2010) (Severe fever with thrombocytopenia virus) reference strain
1 entry
Salmonella phage IKe (Bacteriophage IKe) reference strain
1 entry
Semliki forest virus (SFV) reference strain
1 entry
Seneca Valley virus (isolate -/United States/SSV-001/2002) (SVV) reference strain
1 entry
Sindbis virus (SINV) reference strain
1 entry
Uukuniemi virus (strain S23) (UUKV) reference strain
1 entry
Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain
1 entry
Vesicular stomatitis Indiana virus (strain San Juan) (VSIV) reference strain
1 entry
Vesicular stomatitis New Jersey virus (strain Ogden subtype Concan) (VSNJV) reference strain
1 entry
Xanthomonas phage phiLf (Bacteriophage phi-Lf) reference strain
1 entry
Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus) reference strain
1 entry
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
1 entry
Alphavirus salmon subtype 1 (SAV1) (Salmon pancreas disease virus subtype 1)
1 entry
Alphavirus salmon subtype 2 (SAV2) (Sleeping disease virus)
1 entry
Alphavirus salmon subtype 3 (SAV3) (Norwegian salmonid alphavirus)
1 entry
Aura virus (AURAV)
1 entry
Barmah forest virus (BFV)
1 entry
Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)
1 entry
Bovine herpesvirus 1.1 (strain P8-2) (BoHV-1) (Infectious bovine rhinotracheitis virus)
1 entry
Bovine herpesvirus 1.2 (strain ST) (BoHV-1) (Infectious bovine rhinotracheitis virus)
1 entry
Bovine respiratory syncytial virus (strain Copenhagen) (BRS)
1 entry
Bovine respiratory syncytial virus (strain Rb94) (BRS)
1 entry
Canine parvovirus type 2 (CPV-2)
1 entry
Canine parvovirus type 2 (isolate Dog/United States/CPV-N/1978) (CPV-2)
1 entry
Canine parvovirus type 2 (isolate Dog/United States/CPV-b/1978) (CPV-2)
1 entry
Canine parvovirustype 2 (isolate Dog/United States/CPV-d/1988) (CPV-2)
1 entry
Cercopithecine herpesvirus 1 (CeHV-1) (Simian herpes B virus)
1 entry
Chikungunya virus (strain 37997) (CHIKV)
1 entry
Chikungunya virus (strain Nagpur) (CHIKV)
1 entry
Classical swine fever virus (strain Alfort/Tuebingen) (CSFV) (Hog cholera virus)
1 entry
Classical swine fever virus (strain Brescia) (CSFV) (Hog cholera virus)
1 entry
Dabie bandavirus (Severe fever with thrombocytopenia virus) (Huaiyangshan banyangvirus)
1 entry
Eastern equine encephalitis virus (EEEV) (Eastern equine encephalomyelitis virus)
1 entry
Enterobacteria phage f1 (Bacteriophage f1)
1 entry
Enterobacteria phage fd (Bacteriophage fd)
1 entry
Equine herpesvirus 1 (strain AB1) (EHV-1) (Equine abortion virus)
1 entry
Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)
1 entry
Equine herpesvirus 1 (strain Kentucky D) (EHV-1) (Equine abortion virus)
1 entry
Escherichia phage SECphi27
1 entry
Getah virus (GETV)
1 entry
Hepatitis E virus genotype 1 (isolate Human/Burma) (HEV-1)
1 entry
Hepatitis E virus genotype 1 (isolate Human/India/Hyderabad) (HEV-1)
1 entry
Hepatitis E virus genotype 1 (isolate Human/Myanmar/HEVNE8L) (HEV-1)
1 entry
Hepatitis E virus genotype 1 (isolate Human/Pakistan/Sar-55) (HEV-1)
1 entry
Human cytomegalovirus (strain 1042) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 119) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 2387) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 4654) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 5035) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 5040) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 5160) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain 5508) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain PT) (HHV-5) (Human herpesvirus 5)
1 entry
Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)
1 entry
Human enterovirus 71 (strain 7423/MS/87) (EV71) (EV-71)
1 entry
Human herpesvirus 1 (strain Angelotti) (HHV-1) (Human herpes simplex virus 1)
1 entry
Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1)
1 entry
Human herpesvirus 1 (strain HZT) (HHV-1) (Human herpes simplex virus 1)
1 entry
Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)
1 entry
Human herpesvirus 1 (strain Patton) (HHV-1) (Human herpes simplex virus 1)
1 entry
Human herpesvirus 2 (strain 333) (HHV-2) (Human herpes simplex virus 2)
1 entry
Human respiratory syncytial virus
1 entry
Human respiratory syncytial virus A (strain A2)
1 entry
Human respiratory syncytial virus A (strain RSS-2)
1 entry
Human respiratory syncytial virus B (strain 18537)
1 entry
Lactococcus phage p2 (Lactococcus lactis bacteriophage p2)
1 entry
Mayaro virus (strain Brazil) (MAYV)
1 entry
Middelburg virus
1 entry
Nipah virus
1 entry
O'nyong-nyong virus (strain Gulu) (ONNV)
1 entry
O'nyong-nyong virus (strain Igbo Ora) (ONNV) (Igbo Ora virus)
1 entry
O'nyong-nyong virus (strain SG650) (ONNV)
1 entry
Punta toro phlebovirus
1 entry
Reston ebolavirus (strain Philippines-96) (REBOV) (Reston Ebola virus)
1 entry
Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus)
1 entry
Reston ebolavirus (strain Siena/Philippine-92) (REBOV) (Reston Ebola virus)
1 entry
Rift valley fever virus (RVFV)
1 entry
Ross river virus (strain NB5092) (RRV)
1 entry
Ross river virus (strain T48) (RRV)
1 entry
Sagiyama virus (SAGV)
1 entry
Sheep pulmonary adenomatosis virus (Jaagsiekte sheep retrovirus) (JSRV)
1 entry
Sindbis virus subtype Ockelbo (strain Edsbyn 82-5) (OCKV) (Ockelbo virus)
1 entry
Sudan ebolavirus (strain Boniface-76) (SEBOV) (Sudan Ebola virus)
1 entry
Sudan ebolavirus (strain Human/Uganda/Gulu/2000) (SEBOV) (Sudan Ebola virus)
1 entry
Sudan ebolavirus (strain Maleo-79) (SEBOV) (Sudan Ebola virus)
1 entry
Suid herpesvirus 1 (strain Rice) (SuHV-1) (Pseudorabies virus (strain Rice))
1 entry
Tai Forest ebolavirus (strain Cote d'Ivoire-94) (TAFV) (Cote d'Ivoire Ebola virus)
1 entry
Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)
1 entry
Venezuelan equine encephalitis virus (strain 3880) (VEEV)
1 entry
Venezuelan equine encephalitis virus (strain Everglades Fe3-7c) (VEEV)
1 entry
Venezuelan equine encephalitis virus (strain Mena II) (VEEV)
1 entry
Venezuelan equine encephalitis virus (strain P676) (VEEV)
1 entry
Venezuelan equine encephalitis virus (strain TC-83) (VEEV)
1 entry
Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV)
1 entry
Vesicular stomatitis Indiana virus (strain 85CLB South America) (VSIV)
1 entry
Vesicular stomatitis Indiana virus (strain 94GUB Central America) (VSIV)
1 entry
Vesicular stomatitis Indiana virus (strain 98COE North America) (VSIV)
1 entry
Vesicular stomatitis Indiana virus (strain Glasgow) (VSIV)
1 entry
Vesicular stomatitis Indiana virus (strain Mudd-Summers) (VSIV)
1 entry
Vesicular stomatitis Indiana virus (strain Orsay) (VSIV)
1 entry
Western equine encephalitis virus (WEEV)
1 entry
Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus)
1 entry
Zaire ebolavirus (strain Gabon-94) (ZEBOV) (Zaire Ebola virus)
1 entry