Viral penetration via permeabilization of host membrane (kw:KW-1173)
Some non-enveloped viruses induce local permeabilization of host endosomal membrane to allow virus capsid penetration into the cytoplasm. This is
achieved through the interaction between the host membrane and a membrane-penetration protein associated with the capsid.
Viral membrane-penetration protein might require first to be activated, mostly through endosomal acidic pH or receptor binding to display its membrane penetrating activity.
Interestingly it has been shown for rotavirus that the proteins responsible for membrane permeabilization share common mechanisms with enveloped virus fusion proteins
.
Prokaryotic dsRNA viruses also have a membrane-interacting component associated to their capsid. Virus entry causes depolarization of the host cell membrane. As for other dsRNA viruses, this membrane-interacting component might thus induce permeabilization of the cell membrane
.
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Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)120 entries grouped by strain
2 entries
Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2) reference strain
1 entry
Aedes albopictus densovirus (isolate Boublik/1994) (AalDNV) reference strain
1 entry
Aleutian mink disease parvovirus (strain G) (ADV) reference strain
1 entry
Aquareovirus C (isolate Golden shiner/USA/GSRV/1977) (AQRV-C) reference strain
1 entry
Aquareovirus G (isolate American grass carp/USA/PB01-155/-) (AQRV-G) reference strain
1 entry
Bluetongue virus 10 (isolate USA) (BTV 10) reference strain
1 entry
Bovine parvovirus 1 (BPV-1) reference strain
1 entry
Human parvovirus B19 (strain HV) (HPV B19) reference strain
1 entry
JC polyomavirus (JCPyV) (JCV) reference strain
1 entry
Junonia coenia densovirus (isolate pBRJ/1990) (JcDNV) reference strain
1 entry
Murine minute virus (strain MVM prototype) (MVM) (Murine minute virus (strain MVM(p))) reference strain
1 entry
Nodamura virus (strain Mag115) (NoV) reference strain
1 entry
Reovirus type 1 (strain Lang) (T1L) (Mammalian orthoreovirus 1) reference strain
1 entry
Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)) reference strain
1 entry
Rotavirus A (strain RVA/Human/United States/D/1974/G1P1A[8]) (RV-A) reference strain
1 entry
Rotavirus A (strain RVA/SA11-Both/G3P5B[2]) (RV-A) (Simian Agent 11 (strain Both)) reference strain
1 entry
Rotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C) reference strain
1 entry
Rotavirus X (strain RVX/Human/China/NADRV-J19/1997/GXP[X]) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-J19)) reference strain
1 entry
Simian virus 40 (SV40) reference strain
1 entry
Aedes densonucleosis virus (strain GKV 002 002) (Aedes densovirus)
1 entry
African horse sickness virus (AHSV) (Orbivirus alphaequi)
1 entry
African horse sickness virus 6 (AHSV-6)
1 entry
African horse sickness virus 9 (AHSV-9)
1 entry
BK polyomavirus (BKPyV) (Human polyomavirus 1)
1 entry
BK polyomavirus (strain AS) (BKPyV)
1 entry
Bluetongue virus 1 (isolate Australia) (BTV 1)
1 entry
Bluetongue virus 1 (isolate South Africa) (BTV 1)
1 entry
Bluetongue virus 11 (isolate USA) (BTV 11)
1 entry
Bluetongue virus 13 (isolate USA) (BTV 13)
1 entry
Bluetongue virus 17 (isolate USA) (BTV 17)
1 entry
Bluetongue virus 2 (isolate USA) (BTV 2)
1 entry
Boolarra virus (BoV)
1 entry
Broadhaven virus (BRD)
1 entry
Canine parvovirus type 2 (CPV-2)
1 entry
Canine parvovirus type 2 (isolate Dog/United States/CPV-N/1978) (CPV-2)
1 entry
Canine parvovirus type 2 (isolate Dog/United States/CPV-b/1978) (CPV-2)
1 entry
Canine parvovirus type 2 (strain Dog/United States/780929/-) (CPV-2)
1 entry
Canine parvovirustype 2 (isolate Dog/United States/CPV-d/1988) (CPV-2)
1 entry
Diatraea saccharalis densovirus (DsDNV)
1 entry
Epizootic hemorrhagic disease virus 1 (EHDV-1)
1 entry
Feline panleukopenia virus (FPV)
1 entry
Feline panleukopenia virus (strain 193) (FPV)
1 entry
Flock house virus (FHV)
1 entry
Galleria mellonella densovirus (GmDNV)
1 entry
Hamster parvovirus H1
1 entry
Human parvovirus B19 (isolate AU) (HPV B19)
1 entry
Mink enteritis virus (strain Abashiri) (MEV)
1 entry
Murine minute virus (strain MVMi) (MVM) (Murine parvovirus)
1 entry
Pariacoto virus (PaV)
1 entry
Parvovirus LuIII
1 entry
Porcine parvovirus (strain 90HS) (PPV)
1 entry
Porcine parvovirus (strain Kresse) (PPV)
1 entry
Porcine parvovirus (strain NADL-2) (PPV)
1 entry
Reovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2)
1 entry
Reovirus type 3 (strain Dearing) (T3D) (Mammalian orthoreovirus 3)
1 entry
Rotavirus A (isolate RVA/Cat/Japan/FRV-1/1986/G3P3[9]) (RV-A) (Rotavirus A (isolate FRV1))
1 entry
Rotavirus A (isolate RVA/Cat/Japan/FRV64/1989/G3P5B[3]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/Germany/993/1983/G18P[17]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/India/Hg18/2000/G15P[21]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/Japan/KK3/1983/G10P8[11]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/South/Africa/Offal agent/1965/G8P6[1]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/Thailand/61A/1988/G10P7[5]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/Thailand/A44/1988/G10P8[11]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/Thailand/A5/1988/G8P6[1]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/United States/B223/1983/G10P8[11]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Cow/United States/VMRI/1988/G6P[5]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Dog/United States/Cu-1/1982/G3P5A[3]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Dog/United States/K9/1981/G3P5A[3]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Equine/Japan/HO-5/1980/G3P[X]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Equine/United Kingdom/H2/1976/G3P4[12]) (RV-A) (Rotavirus A (isolate H-2))
1 entry
Rotavirus A (isolate RVA/Equine/United Kingdom/L338/1988/G13P12[18]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/Australia/McN13/1980/G3P2A[6]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/Belgium/B4106/2000/G3P11[14]) (RV-A) (Rotavirus A (isolate B4106))
1 entry
Rotavirus A (isolate RVA/Human/India/116E/1986/G9P8[11]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/Israel/RO1845/1993/G3P5A[3]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/Italy/VA70/1975/G4P1A[8]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/Sweden/1076/1983/G2P2A[6]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/Thailand/Mc35/1992/G10P11[14]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/United Kingdom/A64/1987/G10P11[14]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Human/United States/WI61/1983/G9P1A[8]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Monkey/United States/TUCH/2003/G3P[24]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Mouse/Brazil/EHP/1981/G16P[20]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Mouse/United States/Eb/1982/G16P10[16]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Pig/Australia/CRW-8/1987/G3P9[7]) (RV-A)
1 entry
Rotavirus A (isolate RVA/Pig/Venezuela/A46/1985/G5P13[13]) (RV-A)
1 entry
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) (RV-A)
1 entry
Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) (RV-A)
1 entry
Rotavirus A (strain RVA/Cow/United Kingdom/UK/1975/G6P7[5]) (RV-A)
1 entry
Rotavirus A (strain RVA/Cow/United States/B641/XXXX/G6P7[5]) (RV-A)
1 entry
Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1]) (RV-A) (Rotavirus A (strain Nebraska calf diarrhea virus))
1 entry
Rotavirus A (strain RVA/Cow/United States/WC3/1981/G6P7[5]) (RV-A) (Rotavirus (strain Wistar calf 3))
1 entry
Rotavirus A (strain RVA/Equine/United States/FI-14/1980/G3P4[12]) (RV-A) (Rotavirus A (strain FI14))
1 entry
Rotavirus A (strain RVA/Human/Australia/RV-5/1981/G2P1B[4]) (RV-A) (Rotavirus A (strain RV5))
1 entry
Rotavirus A (strain RVA/Human/Indonesia/69M/1980/G8P4[10]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Japan/AU-1/1982/G3P3[9]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Japan/K8/1977/G1P3A[9]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Japan/KU/1995/G1P1A[8]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Japan/MO/1982/G3P1A[8]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Japan/YO/1977/G3P1A[8]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Philippines/L26/1987/G12P1B[4]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/United Kingdom/ST3/1975/G4P2A[6]) (RV-A) (Rotavirus A (strain St. Thomas 3))
1 entry
Rotavirus A (strain RVA/Human/United States/DS-1/1976/G2P1B[4]) (RV-A) (Rotavirus A (strain DS1))
1 entry
Rotavirus A (strain RVA/Human/United States/P/1974/G3P1A[8]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) (RV-A)
1 entry
Rotavirus A (strain RVA/Human/Venezuela/M37/1982/G1P2A[6]) (RV-A)
1 entry
Rotavirus A (strain RVA/Monkey/United States/RRV/1975/G3P5B[3]) (RV-A)
1 entry
Rotavirus A (strain RVA/Pig/Mexico/YM/1983/G11P9[7]) (RV-A)
1 entry
Rotavirus A (strain RVA/Pig/United States/Gottfried/1983/G4P2B[6]) (RV-A)
1 entry
Rotavirus A (strain RVA/Pig/United States/OSU/1977/G5P9[7]) (RV-A) (Rotavirus A (strain Ohio State University))
1 entry
Rotavirus A (strain RVA/Rabbit/United States/ALA/XXXX/G3P11[14]) (RV-A) (Rotavirus A (strain Alabama))
1 entry
Rotavirus A (strain RVA/SA11-4F/G3P6[1]) (RV-A) (Simian Agent 11 (strain 4F))
1 entry
Rotavirus A (strain RVA/SA11-FEM/G3P6[1]) (RV-A) (Simian Agent 11 (strain FEM))
1 entry
Rotavirus A (strain RVA/SA11-SEM/G3P5B[2]) (RV-A) (Simian Agent 11 (strain SEM))
1 entry
Rotavirus B (isolate RVB/Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))
1 entry
Rotavirus B (isolate RVB/Rat/United States/IDIR/1984/G1P[X]) (RV-B) (Rotavirus B (isolate infectious diarrhea of infant rats))
1 entry
Rotavirus C (isolate RVC/Cow/Japan/Shintoku/1991/G2P[3]) (RV-C)
1 entry
Rotavirus C (strain RVC/Pig/United States/Cowden/1980) (RV-C)
1 entry
Rotavirus X (isolate RVX/Human/Bangladesh/NADRV-B219/2002/GXP[X]) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-B219))
1 entry