Bromoviridae (taxid:39740)

VIRION

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Non enveloped, icosahedral or bacilliform 26-35 nm in diameter. Symmetry icosahedral (T = 3, or T = 1). Three genomic and one subgenomic segments are encapsidated in distinct particles, resulting in several different types of virion.
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GENOME

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Segmented, tripartite linear ssRNA(+) genome composed of RNA1, RNA2, RNA3. Each genomic segment has a 3' tRNA-like structure and a 5'cap.

GENE EXPRESSION

Genomic RNAs serve as messenger RNAs. RNA1 and RNA2 encode respectively proteins 1a and 2a, both involved in genome replication and internal transcription of sgRNA4 from the minus-strand copy of RNA3. RNA3 and sgRNA4 are translated respectively into movement and capsid proteins.
Cucumovirus and ilarvirus have an additional overlapping ORF2b.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Expression of protein 1a and 2a to produce replication proteins.
  4. Replication occurs in viral factories made of membrane vesicles derived from the ER (spherules). A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Subgenomic RNA4 is translated producing capsid proteins.
  7. Assembly of new virus particles.
  8. Viral movement protein triggers the formation of tubular structures that mediate virion cell-to-cell transfer via a tubule-guided mechanism.

Host-virus interaction

Suppression of RNA silencing

Cucumovirus (and possibly ilarvirus) protein 2b acts as a suppressor of RNA silencing .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

109 entries grouped by strain

5 entries

Cucumber mosaic virus (strain FNY) (CMV) reference strain

Select_allDeselect_all
2B_CMVFN Suppressor of silencing 2b (Protein 2b)
RDRP_CMVFN RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
1A_CMVFN Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVFN Capsid protein (CP) (Coat protein)
MVP_CMVFN Movement protein (MP) (Protein 3A)

5 entries

Tobacco streak virus (strain WC) (TSV) reference strain

Select_allDeselect_all
RDRP_TOBSV RNA-directed RNA polymerase 2a (2a pol) (EC 2.7.7.48) (2a polymerase)
1A_TOBSV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_TOBSV Capsid protein (CP) (Coat protein)
2B_TOBSV Suppressor of silencing 2b (Protein 2b)
MVP_TOBSV Movement protein (MP) (Protein 3A)

5 entries

Tomato aspermy virus (TAV) reference strain

Select_allDeselect_all
CAPSD_TAV Capsid protein (CP) (Coat protein)
1A_TAV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_TAV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
2B_TAV Suppressor of silencing 2b (Protein 2b)
MVP_TAV Movement protein (MP) (Protein 3A)

4 entries

Alfalfa mosaic virus (strain 425 / isolate Leiden) reference strain

Select_allDeselect_all
CAPSD_AMVLE Capsid protein (CP) (Coat protein)
1A_AMVLE Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_AMVLE RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
MVP_AMVLE Movement protein (MP) (Protein 3A)

4 entries

Brome mosaic virus (BMV) reference strain

Select_allDeselect_all
1A_BMV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_BMV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
CAPSD_BMV Capsid protein (CP) (Coat protein)
MVP_BMV Movement protein (MP) (Protein 3A)

4 entries

Olive latent virus 2 (isolate Italy) (OLV-2) reference strain

Select_allDeselect_all
1A_OLV2I Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_OLV2I RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
CAPSD_OLV2I Capsid protein (CP) (Coat protein)
MVP_OLV2I Movement protein (MP) (Protein 3A)

4 entries

Pelargonium zonate spot virus (isolate Tomato/Italy/1982) (PZSV) (Pelargonium zonate spot virus (isolate Tomato)) reference strain

Select_allDeselect_all
1A_PZSVT Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_PZSVT Capsid protein (CP) (Coat protein)
MVP_PZSVT Movement protein (MP) (Protein 3A)
RDRP_PZSVT RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

5 entries

Cucumber mosaic virus (strain Q) (CMV)

Select_allDeselect_all
1A_CMVQ Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
2B_CMVQ Suppressor of silencing 2b (Protein 2b)
MVP_CMVQ Movement protein (MP) (Protein 3A)
CAPSD_CMVQ Capsid protein (CP) (Coat protein)
RDRP_CMVQ RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Broad bean mottle virus

Select_allDeselect_all
1A_BBMV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_BBMV Capsid protein (CP) (Coat protein)
MVP_BBMV Movement protein (MP) (Protein 3A)
RDRP_BBMV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Cowpea chlorotic mottle virus (CCMV)

Select_allDeselect_all
CAPSD_CCMV Capsid protein (CP) (Coat protein)
1A_CCMV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_CCMV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
MVP_CCMV Movement protein (MP) (Protein 3A)

4 entries

Cucumber mosaic virus (strain Ixora) (CMV)

Select_allDeselect_all
1A_CMVIX Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_CMVIX RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
CAPSD_CMVIX Capsid protein (CP) (Coat protein)
MVP_CMVIX Movement protein (MP) (Protein 3A)

4 entries

Cucumber mosaic virus (strain NT9) (CMV)

Select_allDeselect_all
1A_CMVNT Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_CMVNT RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
CAPSD_CMVNT Capsid protein (CP) (Coat protein)
MVP_CMVNT Movement protein (MP) (Protein 3A)

4 entries

Cucumber mosaic virus (strain Y) (CMV)

Select_allDeselect_all
1A_CMVY Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVY Capsid protein (CP) (Coat protein)
MVP_CMVY Movement protein (MP) (Protein 3A)
RDRP_CMVY RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Peanut stunt virus (strain J) (PSV)

Select_allDeselect_all
1A_PSVJ Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_PSVJ Capsid protein (CP) (Coat protein)
RDRP_PSVJ RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
MVP_PSVJ Movement protein (MP) (Protein 3A)

3 entries

Cucumber mosaic virus (strain As) (CMV)

Select_allDeselect_all
RDRP_CMVAS RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
CAPSD_CMVAS Capsid protein (CP) (Coat protein)
MVP_CMVAS Movement protein (MP) (Protein 3A)

3 entries

Cucumber mosaic virus (strain Iizuka) (CMV)

Select_allDeselect_all
1A_CMVII Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
RDRP_CMVII RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)
CAPSD_CMVII Capsid protein (CP) (Coat protein)

3 entries

Cucumber mosaic virus (strain Kor) (CMV)

Select_allDeselect_all
MVP_CMVKO Movement protein (MP) (Protein 3A)
CAPSD_CMVKO Capsid protein (CP) (Coat protein)
RDRP_CMVKO RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

3 entries

Cucumber mosaic virus (strain O) (CMV)

Select_allDeselect_all
1A_CMVO Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVO Capsid protein (CP) (Coat protein)
MVP_CMVO Movement protein (MP) (Protein 3A)

2 entries

Alfalfa mosaic virus (strain 425 / isolate Madison)

Select_allDeselect_all
CAPSD_AMVMA Capsid protein (CP) (Coat protein)
MVP_AMVMA Movement protein (MP) (Protein 3A)

2 entries

Alfalfa mosaic virus (strain Strasbourg)

Select_allDeselect_all
CAPSD_AMVST Capsid protein (CP) (Coat protein)
MVP_AMVST Movement protein (MP) (Protein 3A)

2 entries

Alfalfa mosaic virus (strain YSMV)

Select_allDeselect_all
CAPSD_AMVYS Capsid protein (CP) (Coat protein)
MVP_AMVYS Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain C7-2) (CMV)

Select_allDeselect_all
CAPSD_CMVC7 Capsid protein (CP) (Coat protein)
MVP_CMVC7 Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain CS) (CMV)

Select_allDeselect_all
MVP_CMVCS Movement protein (MP) (Protein 3A)
CAPSD_CMVCS Capsid protein (CP) (Coat protein)

2 entries

Cucumber mosaic virus (strain FT) (CMV)

Select_allDeselect_all
MVP_CMVFT Movement protein (MP) (Protein 3A)
CAPSD_CMVFT Capsid protein (CP) (Coat protein)

2 entries

Cucumber mosaic virus (strain Kin) (CMV)

Select_allDeselect_all
CAPSD_CMVKI Capsid protein (CP) (Coat protein)
MVP_CMVKI Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain M) (CMV)

Select_allDeselect_all
CAPSD_CMVM Capsid protein (CP) (Coat protein)
MVP_CMVM Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain M48) (CMV)

Select_allDeselect_all
CAPSD_CMVM4 Capsid protein (CP) (Coat protein)
MVP_CMVM4 Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain N) (CMV)

Select_allDeselect_all
MVP_CMVN Movement protein (MP) (Protein 3A)
CAPSD_CMVN Capsid protein (CP) (Coat protein)

2 entries

Cucumber mosaic virus (strain Pepo) (CMV)

Select_allDeselect_all
CAPSD_CMVPE Capsid protein (CP) (Coat protein)
MVP_CMVPE Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain S) (CMV)

Select_allDeselect_all
CAPSD_CMVS Capsid protein (CP) (Coat protein)
MVP_CMVS Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain Trk7) (CMV)

Select_allDeselect_all
MVP_CMVTR Movement protein (MP) (Protein 3A)
CAPSD_CMVTR Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain B) (CMV)

RDRP_CMVB RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

1 entry

Cucumber mosaic virus (strain Banana) (CMV)

CAPSD_CMVBA Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain C) (CMV)

CAPSD_CMVC Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain DKRD) (CMV)

CAPSD_CMVDK Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain E5) (CMV)

CAPSD_CMVE5 Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain FC) (CMV)

CAPSD_CMVFC Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain I17F) (CMV)

CAPSD_CMVI1 Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain K) (CMV)

RDRP_CMVK RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

1 entry

Cucumber mosaic virus (strain MB-8) (CMV)

RDRP_CMVMB RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

1 entry

Cucumber mosaic virus (strain P6) (CMV)

CAPSD_CMVP6 Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain WL) (CMV)

CAPSD_CMVWL Capsid protein (CP) (Coat protein)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Anulavirus ALMMV taxid:1195163

Protein ModelArchive
Coat protein ma-jd-viral-28015
Movement protein (Protein 3A) ma-jd-viral-27080
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19735
Replication protein 1a ma-jd-viral-38445

Blackberry chlorotic ringspot virus taxid:339420

Protein ModelArchive
Coat protein ma-jd-viral-27553
Movement protein (Protein 3A) ma-jd-viral-27846
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19122
Replication protein 1a ma-jd-viral-38461
p2b protein ma-jd-viral-43705

Blueberry shock virus taxid:747056

Protein ModelArchive
Coat protein ma-jd-viral-27835
Movement protein (Protein 3A) ma-jd-viral-28740
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19217
Replication protein 1a ma-jd-viral-38437

Cassava Ivorian bacilliform virus taxid:1464778

Protein ModelArchive
Movement protein (Protein 3A) ma-jd-viral-27083
Putative coat protein ma-jd-viral-28016
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19738
Replication protein 1a ma-jd-viral-38451

Citrus leaf rugose virus taxid:37126

Protein ModelArchive
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19248

Elm mottle virus taxid:56486

Protein ModelArchive
Coat protein ma-jd-viral-27907
Movement protein (Protein 3A) ma-jd-viral-28445
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19249
Replication protein 1a ma-jd-viral-38470

Fragaria chiloensis latent virus taxid:255238

Protein ModelArchive
Coat protein ma-jd-viral-28956
Movement protein (Protein 3A) ma-jd-viral-27918
ORF 3 ma-jd-viral-48155
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19220
Replication protein 1a ma-jd-viral-38476
Secreted protein ma-jd-viral-31942

Gayfeather mild mottle virus taxid:578305

Protein ModelArchive
2b protein ma-jd-viral-30814
Capsid protein (CP) (Coat protein) ma-jd-viral-28639
Movement protein (Protein 3A) ma-jd-viral-27081
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19737
Replication protein 1a ma-jd-viral-38481

Ilarvirus AGLV taxid:1386090

Protein ModelArchive
2b protein ma-jd-viral-43708
Coat protein ma-jd-viral-27550
Movement protein (Protein 3A) ma-jd-viral-27844
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19121
Replication protein 1a ma-jd-viral-38456

Ilarvirus ApMV taxid:12319

Protein ModelArchive
Coat protein ma-jd-viral-27837
Movement protein (Protein 3A) ma-jd-viral-28738

Lilac leaf chlorosis virus taxid:722755

Protein ModelArchive
Coat protein ma-jd-viral-27834
Movement protein (Protein 3A) ma-jd-viral-28741
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19219
Replication protein 1a ma-jd-viral-38468

Olive latent virus 2 (isolate Italy) taxid:650489

Protein ModelArchive
RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48) ma-jd-viral-18927
Replication protein 1a ma-jd-viral-38450

Parietaria mottle virus taxid:64958

Protein ModelArchive
Coat protein ma-jd-viral-27551
Movement protein (Protein 3A) ma-jd-viral-27847

Peanut stunt virus taxid:12313

Protein ModelArchive
Capsid protein (CP) (Coat protein) ma-jd-viral-28640
Movement protein (Protein 3A) ma-jd-viral-27084
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19736
Replication protein 1a ma-jd-viral-38446

Pelargonium zonate spot virus (isolate Tomato/Italy/1982) taxid:650488

Protein ModelArchive
Capsid protein (CP) (Coat protein) ma-jd-viral-49795
Movement protein (MP) (Protein 3A) ma-jd-viral-27082
RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48) ma-jd-viral-19734
Replication protein 1a ma-jd-viral-38442

Privet ringspot virus taxid:2169960

Protein ModelArchive
2b protein ma-jd-viral-43706
Coat protein ma-jd-viral-27552
Movement protein (Protein 3A) ma-jd-viral-27845
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19124
Replication protein 1a ma-jd-viral-38474

Prune dwarf virus taxid:33760

Protein ModelArchive
Replication protein 1a ma-jd-viral-38472

Prunus necrotic ringspot virus taxid:37733

Protein ModelArchive
Coat protein ma-jd-viral-27833
Movement protein (Protein 3A) ma-jd-viral-28742

Spinach latent virus taxid:42680

Protein ModelArchive
Movement protein (Protein 3A) ma-jd-viral-28444
Putative 2b protein ma-jd-viral-44391
Putative coat protein ma-jd-viral-27908
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19250
Replication protein 1a ma-jd-viral-38475

Strawberry necrotic shock virus taxid:243563

Protein ModelArchive
2b protein ma-jd-viral-43707
RNA-directed RNA polymerase 2a (EC 2.7.7.48) ma-jd-viral-19125

Tobacco streak virus (strain WC) taxid:12318

Protein ModelArchive
RNA-directed RNA polymerase 2a (2a pol) (EC 2.7.7.48) (2a polymerase) ma-jd-viral-19123
Suppressor of silencing 2b (Protein 2b) ma-jd-viral-43710