Tobamovirus (taxid:12234)

VIRION

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Non-enveloped, rigid helical rods with a helical symmetry. Virion is about 18 nm in diameter, and 300-310 nm in length.

GENOME

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Monopartite, linear, ssRNA(+) genome of 6.3-6.5 kb. The 3'-terminus has a tRNA-like structure. The 5' terminus has a methylated nucleotide cap (m7G5'pppG).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The 5'-proximal ORFs are directly translated to produce the viral constituents of the replicase complex. RdRp is translated through suppression of termination at the end of ORF1. The small replicase is involved in replication and acts as a suppressor of RNA silencing. The movement proteins and the capsid protein are expressed from separate subgenomic mRNAs.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. The RdRp recognizes internal subgenomic promoters on the negative-sense RNA to transcribe the 3'co-terminal subgenomic RNAs that will generate the capsid protein, movement protein and viral suppressor of RNA silencing (VSR).
  7. Virus assembly in the cytoplasm. Each segment (if multipartite) is encapsidated.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Tobacco mosaic virus 126-kDa small replicase subunit suppresses RNA silencing .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

81 entries grouped by strain

3 entries

Cucumber green mottle mosaic virus (strain watermelon SH) (CGMMV) reference strain

Select_allDeselect_all
RDRP_CGMVS Replicase large subunit (EC 2.7.7.48) (186 kDa protein) [Cleaved into: Replicase small subunit (EC ...
MVP_CGMVS Movement protein (28.8 kDa protein) (Cell-to-cell transport protein)
CAPSD_CGMVS Capsid protein (Coat protein)

3 entries

Sunn-hemp mosaic virus (SHMV) (TMV strain cowpea) reference strain

Select_allDeselect_all
RDRP_SHMV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
CAPSD_SHMV Capsid protein (Coat protein)
MVP_SHMV Movement protein (30 kDa protein) (Cell-to-cell transport protein)

3 entries

Tobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1)) reference strain

Select_allDeselect_all
RDRP_TMV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TMV Movement protein (30 kDa protein) (Cell-to-cell transport protein) [Cleaved into: 27.9 kDa protein; ...
CAPSD_TMV Capsid protein (Coat protein)

3 entries

Turnip vein-clearing virus (TVCV) reference strain

Select_allDeselect_all
RDRP_TVCV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TVCV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TVCV Capsid protein (Coat protein)

3 entries

Youcai mosaic virus (YoMV) reference strain

Select_allDeselect_all
RDRP_YOMV Replicase large subunit (EC 2.7.7.48) (182 kDa protein) [Cleaved into: Replicase small subunit (EC ...
MVP_YOMV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_YOMV Capsid protein (Coat protein)

3 entries

Odontoglossum ringspot virus (isolate Korean Cy) (ORSV-Cy)

Select_allDeselect_all
RDRP_ORSVC Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
CAPSD_ORSVC Capsid protein (Coat protein)
MVP_ORSVC Movement protein (33.4 kDa protein) (Cell-to-cell transport protein)

3 entries

Odontoglossum ringspot virus (isolate Singapore 1) (ORSV)

Select_allDeselect_all
RDRP_ORSVS Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_ORSVS Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_ORSVS Capsid protein (Coat protein)

3 entries

Pepper mild mottle virus (strain Japan) (PMMV-J)

Select_allDeselect_all
RDRP_PMMVJ Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
CAPSD_PMMVJ Capsid protein (Coat protein)
MVP_PMMVJ Movement protein (30 kDa protein) (Cell-to-cell transport protein)

3 entries

Pepper mild mottle virus (strain Spain) (PMMV-S)

Select_allDeselect_all
RDRP_PMMVS Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_PMMVS Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_PMMVS Capsid protein (Coat protein)

3 entries

Tobacco mild green mosaic virus (TMGMV) (TMV strain U2)

Select_allDeselect_all
RDRP_TMGMV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
CAPSD_TMGMV Capsid protein (Coat protein)
MVP_TMGMV Movement protein (28.5 kDa protein) (Cell-to-cell transport protein)

3 entries

Tobacco mosaic virus (strain B935A) (TMV)

Select_allDeselect_all
RDRP_TMVB Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TMVB Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TMVB Capsid protein (Coat protein)

3 entries

Tobacco mosaic virus (strain Korean NC 82) (TMV)

Select_allDeselect_all
RDRP_TMVKR Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TMVKR Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TMVKR Capsid protein (Coat protein)

3 entries

Tobacco mosaic virus (strain OM) (TMV)

Select_allDeselect_all
RDRP_TMVOM Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
CAPSD_TMVOM Capsid protein (Coat protein)
MVP_TMVOM Movement protein (30 kDa protein) (Cell-to-cell transport protein) [Cleaved into: 27.9 kDa protein; ...

3 entries

Tobacco mosaic virus (strain Rakkyo) (TMV-R)

Select_allDeselect_all
RDRP_TMVRA Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TMVRA Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TMVRA Capsid protein (Coat protein)

3 entries

Tobamovirus Ob

Select_allDeselect_all
RDRP_TMOB Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TMOB Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TMOB Capsid protein (Coat protein)

3 entries

Tomato brown rugose fruit virus (isolate TOBRFV/Tomato/Jordan/Tom1-Jo/2015) (ToBRFV)

Select_allDeselect_all
RDRP_TBRFV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TBRFV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TBRFV Capsid protein (Coat protein)

3 entries

Tomato mosaic virus (strain Kazakh K1) (ToMV) (TMV strain K1)

Select_allDeselect_all
RDRP_TOMK1 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TOMK1 Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TOMK1 Capsid protein (Coat protein)

3 entries

Tomato mosaic virus (strain Kazakh K2) (ToMV) (TMV strain K2)

Select_allDeselect_all
RDRP_TOMK2 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TOMK2 Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TOMK2 Capsid protein (Coat protein)

3 entries

Tomato mosaic virus (strain L) (ToMV) (TMV strain tomato)

Select_allDeselect_all
RDRP_TOML Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
MVP_TOML Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_TOML Capsid protein (Coat protein)

3 entries

Tomato mosaic virus (strain S-1) (ToMV)

Select_allDeselect_all
RDRP_TOMS1 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...
CAPSD_TOMS1 Capsid protein (Coat protein)
MVP_TOMS1 Movement protein (30 kDa protein) (Cell-to-cell transport protein)

2 entries

Cucumber green mottle mosaic virus (strain watermelon W) (CGMMV)

Select_allDeselect_all
CAPSD_CGMVW Capsid protein (Coat protein)
MVP_CGMVW Movement protein (28.8 kDa protein) (Cell-to-cell transport protein)

2 entries

Odontoglossum ringspot virus (isolate Japan) (ORSV)

Select_allDeselect_all
CAPSD_ORSVJ Capsid protein (Coat protein)
MVP_ORSVJ Movement protein (33.4 kDa protein) (Cell-to-cell transport protein)

2 entries

Ribgrass mosaic virus (RMV)

Select_allDeselect_all
MVP_RMV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
CAPSD_RMV Capsid protein (Coat protein)

1 entry

Paprika mild mottle virus (PaMMV)

CAPSD_PMMV Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain Italian) (PMMV-I)

CAPSD_PMMVI Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain P0) (PMMV)

CAPSD_PMMV0 Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain P1) (PMMV)

CAPSD_PMMV1 Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain P2) (PMMV)

CAPSD_PMMV2 Capsid protein (Coat protein)

1 entry

Ribgrass mosaic virus (strain CAB) (RMV)

CAPSD_RMVCA Capsid protein (Coat protein)

1 entry

Ribgrass mosaic virus (strain Hr) (RMV) (TMV strain Holmes ribgrass)

CAPSD_RMVHR Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain 06) (TMV-06)

CAPSD_TMV06 Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain Dahlemense) (TMV)

CAPSD_TMVDA Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain ER) (TMV)

CAPSD_TMVER Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain Kokubu) (TMV)

CAPSD_TMVKO Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain O) (TMV)

CAPSD_TMVO Capsid protein (Coat protein)

1 entry

Tomato mosaic virus (strain Korean) (ToMV)

CAPSD_TOMKO Capsid protein (Coat protein)

1 entry

Tomato mosaic virus (strain LII) (ToMV)

MVP_TOML2 Movement protein (30 kDa protein) (Cell-to-cell transport protein)

1 entry

Tomato mosaic virus (strain LIIa) (ToMV)

MVP_TOMLA Movement protein (30 kDa protein) (Cell-to-cell transport protein)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Bell pepper mottle virus taxid:368735

Protein ModelArchive
126 kDa replicase ma-jd-viral-38457
Capsid protein ma-jd-viral-23819
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27437
Replicase large subunit ma-jd-viral-19492

Brugmansia mild mottle virus taxid:402399

Protein ModelArchive
125 kDa replicase ma-jd-viral-38454
Capsid protein ma-jd-viral-23823
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27443

Cactus mild mottle virus taxid:229030

Protein ModelArchive
Capsid protein ma-jd-viral-23806
Movement protein ma-jd-viral-28533
Replicase ma-jd-viral-38458

Clitoria yellow mottle virus taxid:1128119

Protein ModelArchive
Capsid protein ma-jd-viral-23802
Movement protein ma-jd-viral-27454
Replicase ma-jd-viral-38479

Frangipani mosaic virus taxid:99585

Protein ModelArchive
129 kDa replicase ma-jd-viral-38455
Capsid protein ma-jd-viral-23803
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27447

Hibiscus latent Fort Pierce virus taxid:233051

Protein ModelArchive
128 kDa replicase (128kDa protein) ma-jd-viral-38465
31 kDa movement protein ma-jd-viral-27449
Capsid protein ma-jd-viral-23816

Hibiscus latent Singapore virus taxid:185955

Protein ModelArchive
Capsid protein ma-jd-viral-23825
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27444
Replicase ma-jd-viral-38447

Maracuja mosaic virus taxid:368736

Protein ModelArchive
126 kDa replicase ma-jd-viral-38462
Capsid protein ma-jd-viral-23810
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27453
Replicase large subunit ma-jd-viral-19513

Passion fruit mosaic virus taxid:1032457

Protein ModelArchive
125 kDa protein ma-jd-viral-38480
Capsid protein ma-jd-viral-23808
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27448

Plumeria mosaic virus taxid:1501716

Protein ModelArchive
Capsid protein ma-jd-viral-23807
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27442
Replicase small protein ma-jd-viral-38477

Rattail cactus necrosis-associated virus taxid:1123754

Protein ModelArchive
128 kDa replication protein ma-jd-viral-38453
Capsid protein ma-jd-viral-23813
Movement protein (Cell-to-cell transport protein) ma-jd-viral-28534

Rehmannia mosaic virus taxid:425279

Protein ModelArchive
126 kDa protein ma-jd-viral-38449
Capsid protein ma-jd-viral-23821
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27439

Ribgrass mosaic virus taxid:51680

Protein ModelArchive
Capsid protein ma-jd-viral-23805
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27445
RNA replicase component ma-jd-viral-38464

Tomato brown rugose fruit virus taxid:1761477

Protein ModelArchive
Capsid protein ma-jd-viral-23818

Tomato brown rugose fruit virus (isolate TOBRFV/Tomato/Jordan/Tom1-Jo/2015) taxid:2654645

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-23818
Movement protein (30 kDa protein) (Cell-to-cell transport protein) ma-jd-viral-27450
Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) (RNA-directed RNA... ma-jd-viral-38440

Tomato mosaic virus taxid:12253

Protein ModelArchive
126 kDa protein (126 kDa replicase) (Methyltranferase/helicase) ma-jd-viral-38439
Capsid protein ma-jd-viral-23820
Capsid protein ma-jd-viral-23820
Capsid protein ma-jd-viral-23820
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27446

Tomato mosaic virus (strain L) taxid:12252

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-23820
Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) (RNA-directed RNA... ma-jd-viral-38439

Tomato mottle mosaic virus taxid:1391702

Protein ModelArchive
Capsid protein ma-jd-viral-23822
Capsid protein ma-jd-viral-23822
Methyltransferase/helicase ma-jd-viral-38441
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27441

Tropical soda apple mosaic virus taxid:327387

Protein ModelArchive
125 kDa replicase ma-jd-viral-38435
Capsid protein ma-jd-viral-23824
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27440

Turnip vein-clearing virus taxid:29272

Protein ModelArchive
Capsid protein ma-jd-viral-23804
Capsid protein (Coat protein) ma-jd-viral-23804
Movement protein (30 kDa protein) (Cell-to-cell transport protein) ma-jd-viral-27436
Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) (RNA-directed RNA... ma-jd-viral-38434

Yellow tailflower mild mottle virus taxid:1416026

Protein ModelArchive
129k replicase protein ma-jd-viral-38478
Capsid protein ma-jd-viral-23809
Movement protein (Cell-to-cell transport protein) ma-jd-viral-27451

Youcai mosaic virus taxid:228578

Protein ModelArchive
Capsid protein ma-jd-viral-23811
Capsid protein (Coat protein) ma-jd-viral-23811
Movement protein (30 kDa protein) (Cell-to-cell transport protein) ma-jd-viral-27438