Picovirinae (taxid:542836)
VIRION
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Non-enveloped, head-tail structure. Head is about 54 nm in diameter. The tail is non-contractile and has a collar with 12 appendages. The capsid is icosahedral with a T=3 symmetry.
GENOME
Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes.
GENE EXPRESSION
ENZYMES
- DNA dependent DNA polymerase [DNA pol]
- Protease (Peptidase G2) [Pre-neck appendage protein]
- Endolysin
REPLICATION
CYTOPLASMIC
- Adsorption: the phage attaches to the target cell via its tail fibers.
- Ejection by short tail system: viral DNA is injected into the periplams of the host cell.
- Transcription and translation of the early genes
- Replication of genomic DNA by Strand displacement by viral DNA polymerase, formation of viral genome concatemers.
- Transcription and translation of late genes
- Assembly of empty procapsids and viral genome packaging.
- Mature virions are released from the cell by lysis.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)82 entries grouped by protein
3 entries
Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
3 entries
Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
4 entries
Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
5 entries
DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
3 entries
Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase) (Protein p15)
3 entries
Pre-neck appendage protein (Gene product 12) (gp12) (Late protein GP12) (NP1) (Protein p12)
2 entries
DNA replication protein 1 (Gene product 1) (gp1)
2 entries
Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13)
3 entries
Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
3 entries
Gene product 16.6 (gp16.6) (Protein p16.6)
3 entries
DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
3 entries
Gene product 16.8 (gp16.8) (Protein p16.8)
3 entries
Gene product 16.9 (gp16.9) (Protein p16.9)
3 entries
DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
2 entries
Gene product 5.5 (gp5.5) (Gene product 5B) (gp5B) (Protein p5.5)
3 entries
Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14)
4 entries
Histone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded DNA-binding protein p6) (Gene product 6) (gp6) (Histone-like binding protein) (Nucleoid-associated protein p6) (Protein p6)
2 entries
Protein p56
3 entries
DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
3 entries
Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) (gp19) (Head-to-tail connector) (Probable portal protein) (Protein p10) (Upper collar protein)
3 entries
Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) (Scaffold protein)
4 entries
Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
4 entries
DNA terminal protein (Gene product 3) (gp3) (Protein p3)
2 entries
Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
3 entries
Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)
1 entry
Morphogenesis protein 1 (Late protein GP13)
1 entry
Early protein GP17
1 entry
Early protein GP1A
2 entries
Late genes activator (Early protein GP4)
1 entry