Picovirinae

VIRION

Non-enveloped, head-tail structure. Head is about 54 nm in diameter. The tail is non-contractile and has a collar with 12 appendages. The capsid is icosahedral with a T=3 symmetry.

GENOME

Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription and translation of early genes
  4. Replication of genomic DNA by the viral DNA polymerase, formation of viral genome concatemers.
  5. Transcription and translation of late genes
  6. Assembly of empty procapsids and viral genome packaging.
  7. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

82 entries grouped by strain (browse by keywords)

24 entries

Bacillus phage phi29 (Bacteriophage phi-29) reference strain

Select_allDeselect_all
ENLYS_BPPH2 Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase) (Protein p15)
DIT9_BPPH2 Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
CAPSF_BPPH2 Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
HOLIN_BPPH2 Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14) [Includes: Holin (Lysis ...
GP17_BPPH2 DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
GP167_BPPH2 DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP166_BPPH2 Gene product 16.6 (gp16.6) (Protein p16.6)
NP_BPPH2 Histone-like protein p6 (Double-stranded DNA-binding protein p6) (Gene product 6) (gp6) ...
PORTL_BPPH2 Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) (gp19) (Head-to-tail ...
GP13_BPPH2 Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13) [Includes: Lysozyme-like glycosidase ...
GP1_BPPH2 DNA replication protein 1 (Gene product 1) (gp1)
GP55_BPPH2 Gene product 5.5 (gp5.5) (Gene product 5B) (gp5B) (Protein p5.5)
FIB12_BPPH2 Pre-neck appendage protein (Gene product 12) (gp12) (NP1) (Protein p12) [Cleaved into: gp12*]
GP168_BPPH2 Gene product 16.8 (gp16.8) (Protein p16.8)
DPOL_BPPH2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
SCAF_BPPH2 Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) ...
CAPSD_BPPH2 Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
P56_BPPH2 Protein p56
SSB_BPPH2 Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
GP169_BPPH2 Gene product 16.9 (gp16.9) (Protein p16.9)
PKG16_BPPH2 DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
TF4_BPPH2 Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
TERM_BPPH2 Primer terminal protein (TP) (DNA terminal protein) (Gene product 3) (gp3) (Protein p3) (Terminal ...
TUB11_BPPH2 Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)

4 entries

Bacillus phage Nf (Bacteriophage Nf) reference strain

Select_allDeselect_all
NP_BPNF Double-stranded DNA-binding protein (Gene product 6) (gp6) (Nucleoid-associated protein p6) (Protein ...
DIT9_BPNF Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9) (Tail protein)
DPOL_BPNF DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
SSB_BPNF Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)

26 entries

Bacillus phage PZA (Bacteriophage PZA)

Select_allDeselect_all
ENLYS_BPPZA Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase) (Protein p15)
CAPSF_BPPZA Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
GP167_BPPZA DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
NP_BPPZA Histone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded DNA-binding protein ...
FIB12_BPPZA Preneck appendage protein (Gene product 12) (gp12) (Protein p12) [Cleaved into: gp12*]
GP168_BPPZA Gene product 16.8 (gp16.8) (Protein p16.8)
PORTL_BPPZA Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) (gp19) (Head-to-tail ...
GP55_BPPZA Gene product 5B (gp5B) (Protein p5B)
GP169_BPPZA Gene product 16.9 (gp16.9) (Protein p16.9)
DIT9_BPPZA Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
CAPSD_BPPZA Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
GP1_BPPZA DNA replication protein 1 (Gene product 1C) (gp1C)
GP166_BPPZA Gene product 16.6 (gp16.6) (Protein p16.6)
DPOL_BPPZA DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
GP13_BPPZA Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13) [Includes: Lysozyme-like glycosidase ...
SCAF_BPPZA Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) ...
P56_BPPZA Protein p56
GP165_BPPZA Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
GP17_BPPZA DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
VG1A_BPPZA Early protein GP1A
HOLIN_BPPZA Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14) [Includes: Holin (Lysis ...
TERM_BPPZA DNA terminal protein (Gene product 3) (gp3) (Protein p3)
SSB_BPPZA Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TUB11_BPPZA Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)
TF4_BPPZA Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
PKG16_BPPZA DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)

1 entry

Bacillus phage phi29 (Bacteriophage phi-29)

GP165_BPPH2 Gene product 16.5 (gp16.5) (Protein p16.5)

17 entries

Bacillus phage B103 (Bacteriophage B103)

Select_allDeselect_all
ENLYS_BPB03 Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase) (Protein p15)
CAPSF_BPB03 Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
HOLIN_BPB03 Antiholin (Gene product 14) (gp14) (Protein p14) [Includes: Holin]
PORTL_BPB03 Portal protein (Gene product 10) (gp10) (Head-to-tail connector) (Upper collar protein)
FIB12_BPB03 Pre-neck appendage protein (Gene product 12) (gp12) (Late protein GP12) (NP1) (Protein p12)
DIT9_BPB03 Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
CAPSD_BPB03 Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
DPOL_BPB03 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
PKG16_BPB03 DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
SCAF_BPB03 Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) ...
NP_BPB03 Histone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded DNA-binding protein ...
SSB_BPB03 Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
VG13_BPB03 Morphogenesis protein 1 (Late protein GP13) [Includes: Lysozyme-like glycosidase (EC 3.2.1.-); ...
VG17_BPB03 Early protein GP17
TUB11_BPB03 Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)
TERM_BPB03 DNA terminal protein (Gene product 3) (gp3) (Protein p3)
VG4_BPB03 Late genes activator (Early protein GP4)

3 entries

Bacillus phage Nf (Bacteriophage Nf)

Select_allDeselect_all
VG85_BPNF Head fiber protein (Late protein GP8.5)
TERM_BPNF DNA terminal protein (Gene product 3) (gp3) (Protein p3)
VG4_BPNF Late genes activator (Early protein GP4) (GPF)

6 entries

Bacillus phage phi15 (Bacteriophage phi-15)

Select_allDeselect_all
GP165_BPPH5 Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
GP169_BPPH5 Gene product 16.9 (gp16.9) (Protein p16.9)
GP17_BPPH5 DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
GP167_BPPH5 DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP166_BPPH5 Gene product 16.6 (gp16.6) (Protein p16.6)
GP168_BPPH5 Gene product 16.8 (gp16.8) (Protein p16.8)

1 entry

Bacillus phage M2 (Bacteriophage M2)

DPOL_BPM2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)