Mypoviridae (taxid:2501940)

VIRION

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Unknown, discovered using viral metagenomics. Presumably enveloped.

GENOME

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Segmented Negative-stranded RNA linear genome, L segment is about 10 kb, M segment about 3.5 kb and S segment 2.5 kb. Encodes at least three proteins.

Enzymes: RNA dependent RNA polymerase, endonuclease? (Cap snatching).

GENE EXPRESSION

The viral RNA dependent RNA polymerase (L) binds to a promoter on each encapsidated segment, and transcribes the mRNA. These are capped by L protein during synthesis using cap snatching .

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus attaches to host receptors though glycoprotein, and is endocytosed into vesicles in the host cell.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid segments are released in the cytoplasm.
  3. Transcription, viral mRNAs are capped in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsids buds, presumably releasing the virion by exocytosis.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Hubei myriapoda virus 5 taxid:1922934

Protein ModelArchive
Putative glycoprotein ma-jd-viral-40034
Putative nucleoprotein ma-jd-viral-35663