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Cap snatching (kw:KW-1157)

RNAs are capped by a unique viral reaction before viral transcription. A nucleotide sequence of 10 to 20 nt in size is cleaved from the 5' end of host mRNAs by an endonuclease activity and used as an initiator for viral transcription. In this way, canonically capped mRNA is produced by viral transcriptase. This mechanism of using a prefabricated mRNA cap is similar with cellular trans-splicing described in nematodes, flatworms, cnidarians, ascidians, rotifers and euglenozoans .

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Enzymatic reaction
RNA endonuclease
RNA dependent RNA polymerase: Rhea 21248

Cap snatching is a transcription initiation process during which a nucleotide sequence between 10 and 20 nt in size is cleaved from the 5' end of host mRNAs by an endonuclease activity encompassed within the viral RdRp . For Influenza this process occurs in the nucleus whereas for most other segmented (-)RNA viruses this happens in the cytoplasm. The capped leader obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.
The dsRNA L-A virus mediates cap snatching although it does not take the entire cap. m(7)Gp from the cap donor is transferred to the 5' end of the viral transcript, thus preserving the 5' α-and β-phosphates of the transcript in the triphosphate linkage of the final product .

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Viral molecular biology Virus entry
Transcription and replication
Virus exit
Replication cycles
Virion
Enzymes
Viral mRNA capping Cell-type capping
Alpha-type capping
Nido-type capping
Mononega-type capping
VPG cap
Polynega-type cap-snatching
Toti-type cap-snatching
Links Uniprot Keyword: KW-1157
GO ontology: GO:0075526
Virus Arenavirus
Bunyaviridae
Orthomyxoviridae

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

227 entries grouped by strain

2 entries

Influenza A virus (strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/Gd) reference strain

Select_allDeselect_all
PA_I96A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 3EBJ; 3HW3; 3HW4; 3HW5; 3HW6; 8H69; 8KCV

PB2_I96A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 8H69; 9BL5; 9BL6

2 entries

Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain

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PB2_I34A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 2ZTT; 3A1G; 3CW4; 3WI0; 3WI1; 4ENF; 4J2R; 4U6O; 7JYW; 7JYX

PA_I34A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 2ZNL; 4YYL; 4ZHZ; 4ZI0; 4ZQQ; 5FDD; 5FDG; 5I13; 5JHT; 5JHV; 7XGC

2 entries

Influenza B virus (strain B/Lee/1940) reference strain

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PA_INBLE Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_INBLE Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 5EF9; 5EFA; 5EFC; 6XQA

2 entries

Influenza C virus (strain C/Ann Arbor/1/1950) reference strain

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PA_INCAA Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_INCAA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Alethinophid 1 reptarenavirus (isolate AlRrV1/Boa/USA/BC/2009) (Golden Gate virus) reference strain

L_GOGV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Cupixi mammarenavirus (isolate Rat/Brasil/BeAn 119303/1970) (CPXV) reference strain

L_CPXVB RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Hantaan virus (strain 76-118) (Korean hemorrhagic fever virus) reference strain

L_HANTV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

pdb 5IZE; 8C4S; 8C4T; 8C4U; 8C4V; 8P1J; 8P1K; 8P1L; 8P1M; 8P1N; 8QE5; 8QGT; 8QGU; 8QH3; 8QHD

1 entry

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) reference strain

L_LASSJ RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Latino mammarenavirus (isolate Rat/Bolivia/MARU 1924/1965) (LATV) reference strain

L_LATVB RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Lymphocytic choriomeningitis virus (strain Armstrong) (LCMV) reference strain

L_LYCVA RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

pdb 3JSB; 5LTF; 5LTN; 5LTS; 5T2T; 7X6S; 7X6V

1 entry

Oliveros mammarenavirus (isolate Mouse/Argentina/RIID 3229/1990) (OLVV) reference strain

L_OLVVA RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Parana mammarenavirus (isolate Rat/Paraguay/12056/1965) (PARV) (Paran mammarenavirus) reference strain

L_PARVP RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Pirital mammarenavirus (isolate Rat/Venezuela/VAV-488/1995) (PIRV) reference strain

L_PIRVV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Puumala virus (strain Sotkamo/V-2969/81) reference strain

L_PUUMS RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

1 entry

Quaranfil virus (isolate QrfV/Tick/Afghanistan/EG_T_377/1968) (QRFV) reference strain

PB2_QRFVE Polymerase basic protein 2 (PB2)

1 entry

Tacaribe virus (strain Franze-Fernandez) (TCRV) reference strain

L_TACVF RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Thogoto virus (isolate SiAr 126) (Tho) reference strain

PB2_THOGV Polymerase basic protein 2 (PB2) (RNA-directed RNA polymerase subunit P3)

pdb 4CHD; 4CHE; 4CHF; 8P0B; 8P0G; 8P0U; 8Z85; 8Z8J; 8Z8N; 8Z8X; 8Z90; 8Z97; 8Z98; 8Z9H; 8Z9Q; 8Z9R

1 entry

Whitewater Arroyo mammarenavirus (isolate Rat/United States/AV 9310135/1995) (WWAV) reference strain

L_WWAVU RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

2 entries

Influenza A virus (strain A/Ann Arbor/6/1960 H2N2)

Select_allDeselect_all
PA_I60A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I60A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Beijing/39/1975 H3N2)

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PA_I75A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I75A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 4YD0; 5BUH; 5F79; 5JUN; 5JUR

2 entries

Influenza A virus (strain A/Brazil/11/1978 H1N1)

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PA_I77AA Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I77AA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))

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PA_I18A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 7NHA; 7NHC; 7NHX; 7NI0; 7NIK; 7NIL; 7NIR; 7NIS; 7NJ3; 7NJ4; 7NJ5; 7NJ7; 7NK1; 7NK2; 7NK4; 7NK6; 7NK8; 7NKA; 7NKC; 7NKI; 7NKR; 8R60; 8R65

PB2_I18A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 7NHA; 7NHC; 7NHX; 7NI0; 7NIK; 7NIL; 7NIR; 7NIS; 7NJ3; 7NJ4; 7NJ5; 7NJ7; 7NK1; 7NK2; 7NK4; 7NK6; 7NK8; 7NKA; 7NKC; 7NKI; 7NKR; 8R60; 8R65

2 entries

Influenza A virus (strain A/Chicken/Brescia/1902 H7N7)

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PB2_I02A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I02A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Chicken/Hong Kong/96.1/2002 H5N1 genotype Y)

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PA_I02A5 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I02A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Chicken/Hong Kong/YU22/2002 H5N1 genotype Z)

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PB2_I02A6 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 5EG9; 9I2O

PA_I02A6 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Chicken/Pennsylvania/1/1983 H5N2)

Select_allDeselect_all
PB2_I83A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I83A5 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Chicken/Scotland/1959 H5N1)

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PB2_I59A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I59A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Chicken/Victoria/1/1985 H7N7)

Select_allDeselect_all
PB2_I85A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I85A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Chile/1/1983 H1N1)

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PA_I83A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I83A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

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PB2_I96A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I96A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6)

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PB2_I56A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I56A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Duck/England/1/1956 H11N6)

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PB2_I56A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I56A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Duck/Germany/1949 H10N7)

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PB2_I49A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I49A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Duck/Hokkaido/8/1980 H3N8)

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PA_I80A6 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 4W9S

PB2_I80A6 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Duck/Hong Kong/2986.1/2000 H5N1 genotype C)

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PA_I00A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I00A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/England/878/1969 H3N2)

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PA_I69A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I69A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Equine/London/1416/1973 H7N7)

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PA_I73A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I73A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)

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PA_I47A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I47A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Fowl plague virus/Rostock/8/1934 H7N1)

Select_allDeselect_all
PA_I34A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I34A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Goose/Guangxi/345/2005 H5N1 genotype G)

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PA_I05A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I05A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Grey teal/Australia/2/1979 H4N4)

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PB2_I79A7 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I79A7 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Gull/Maryland/704/1977 H13N6)

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PA_I77AF Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I77AF Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Gull/Minnesota/945/1980 H13N6)

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PB2_I80AD Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I80AD Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Henry/1936 H1N1)

Select_allDeselect_all
PA_I36A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I36A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Hickox/1940 H1N1)

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PB2_I40A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I40A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Hong Kong/1/1968 H3N2)

Select_allDeselect_all
PA_I68A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I68A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 4EQK

2 entries

Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)

Select_allDeselect_all
PA_I97A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 7N4K; 7N5C; 7N5P; 7N5Q

PB2_I97A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Hong Kong/5/1983 H3N2)

Select_allDeselect_all
PB2_I83A8 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I83A8 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/India/6263/1980 H1N1)

Select_allDeselect_all
PA_I80AA Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I80AA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Japan/305/1957 H2N2)

Select_allDeselect_all
PA_I57A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I57A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Kitakyushu/159/1993 H3N2)

Select_allDeselect_all
PB2_I93A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I93A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Korea/426/1968 H2N2)

Select_allDeselect_all
PA_I68A5 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I68A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Leningrad/134/17/1957 H2N2)

Select_allDeselect_all
PB2_I57A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I57A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Leningrad/134/1957 H2N2)

Select_allDeselect_all
PA_I57A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I57A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Leningrad/134/47/1957 H2N2)

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PB2_I57A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I57A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)

Select_allDeselect_all
PA_I54A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I54A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Mallard/New York/6750/1978 H2N2)

Select_allDeselect_all
PA_I78A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I78A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Memphis/1/1971 H3N2)

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PB2_I71A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I71A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Memphis/101/1972 H3N2)

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PB2_I72A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I72A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Memphis/102/1972 H3N2)

Select_allDeselect_all
PB2_I72A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I72A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Memphis/110/1976 H3N2)

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PB2_I76A6 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I76A6 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Memphis/18/1978 H3N2)

Select_allDeselect_all
PB2_I78A8 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I78A8 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Memphis/2/1978 H3N2)

Select_allDeselect_all
PB2_I78A7 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I78A7 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Memphis/4/1980 H3N2)

Select_allDeselect_all
PB2_I80A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I80A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)

Select_allDeselect_all
PB2_I00A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I00A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60)) (Influenza A virus (strain A/NT/60/1968 H3N2))

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PA_I68A6 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 6QPG; 6QX3; 6QX8; 6QXE; 6RR7; 8Y7M; 8Y7O

PB2_I68A6 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 6QNW; 6QPG; 6QX3; 6QX8; 6QXE; 6RR7; 8Y7M; 8Y7O

2 entries

Influenza A virus (strain A/Port Chalmers/1/1973 H3N2)

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PB2_I73A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I73A5 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Qu/7/1970 H3N2)

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PA_I70A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I70A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Ruddy Turnstone/New Jersey/47/1985 H4N6)

Select_allDeselect_all
PA_I85A7 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I85A7 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)

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PA_I06A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I06A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Seal/Massachusetts/1/1980 H7N7)

Select_allDeselect_all
PA_I80A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I80A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Singapore/1/1957 H2N2)

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PA_I57A5 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I57A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Swine/Colorado/1/1977 H3N2)

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PB2_I77A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I77A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)

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PA_I30A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 1YN6; 1YN7; 3PQY

PB2_I30A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)

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PA_I61A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I61A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)

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PA_I67A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I67A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Tokyo/3/1967 H2N2)

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PA_I67A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I67A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Turkey/Ireland/1378/1983 H5N8)

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PB2_I83A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I83A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Turkey/Minnesota/833/1980 H4N2)

Select_allDeselect_all
PA_I80A8 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I80A8 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Turkey/Ontario/6118/1968 H8N4)

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PB2_I68A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I68A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Turkey/Wisconsin/1/1966 H9N2)

Select_allDeselect_all
PB2_I66A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I66A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/USA:Albany/12/1951 H1N1)

Select_allDeselect_all
PA_I51A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I51A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)

Select_allDeselect_all
PA_I45A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I45A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Iowa/1943 H1N1)

Select_allDeselect_all
PA_I43A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I43A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)

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PA_I96A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I96A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Phila/1935 H1N1)

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PA_I35A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I35A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)

Select_allDeselect_all
PA_I07A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I07A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USSR/90/1977 H1N1)

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PB2_I77AB Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I77AB Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

2 entries

Influenza A virus (strain A/Udorn/307/1972 H3N2)

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PA_I72A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I72A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 5WL0

2 entries

Influenza A virus (strain A/Victoria/3/1975 H3N2)

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PA_I75A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 2W69

PB2_I75A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 2GMO; 2JDQ; 2VQZ; 2VY6; 2VY7; 2VY8; 4NCE; 4NCM; 4P1U; 4UAD; 4UAE; 4UAF; 6EUV; 6EUY; 7XME

2 entries

Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))

Select_allDeselect_all
PB2_I33A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I33A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 4IUJ; 5IEQ; 5IF2; 5IF5; 5IF7; 5IF8; 5IFB; 5IFC; 5IFD; 5V0U; 6CFP

2 entries

Influenza A virus (strain A/X-31 H3N2)

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PA_I000X Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I000X Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza B virus (strain B/Ann Arbor/1/1966 [cold-adapted])

Select_allDeselect_all
PA_INBAC Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_INBAC Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza B virus (strain B/Ann Arbor/1/1966 [wild-type])

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PA_INBAD Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_INBAD Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza B virus (strain B/Panama/45/1990)

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PA_INBP9 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 6QWL

PB2_INBP9 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 6QWL

2 entries

Influenza C virus (strain C/JJ/1950)

Select_allDeselect_all
PA_INCJJ Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_INCJJ Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza C virus (strain C/Johannesburg/1/1966)

Select_allDeselect_all
PA_INCJH Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 5D98; 5D9A; 6F5P; 6XZD; 6XZG; 6XZP; 6XZQ; 6XZR; 6Y0C

PB2_INCJH Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

pdb 5D98; 5D9A; 6F5P; 6XZD; 6XZG; 6XZP; 6XZQ; 6XZR; 6Y0C

1 entry

Allpahuayo mammarenavirus (isolate Rat/Peru/CLHP-2472/1997) (ALLV)

L_ALLVP RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Andes orthohantavirus (ANDV) (Andes virus)

L_ANDV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

pdb 6Q99

1 entry

Bear Canyon mammarenavirus (isolate Mouse/United States/AV A0070039/2000) (BCNV)

L_BCNVU RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Black Creek Canal orthohantavirus (BCCV) (Black Creek Canal virus)

L_BCCV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Chapare mammarenavirus (isolate Human/Bolivia/810419/2003)

L_CHAVB RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Dobrava-Belgrade orthohantavirus (DOBV) (Dobrava virus)

L_DOBV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

1 entry

Guanarito mammarenavirus (isolate Human/Venezuela/NH-95551/1990) (GTOV)

L_GTOVV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Influenza A virus (strain A/Budgerigar/Hokkaido/1/1977 H4N6)

PB2_I77AG Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/220/1997 H5N1 genotype Gs/Gd)

PA_I97A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/31.2/2002 H5N1 genotype X1)

PA_I02A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/715.5/2001 H5N1 genotype E)

PA_I01A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 6IRL

1 entry

Influenza A virus (strain A/Chicken/Shantou/4231/2003 H5N1 genotype V)

PB2_I03A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Chicken/Weybridge H7N7) (Influenza A virus (strain A/FPV/Weybridge H7N7))

PB2_I000F Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Equine/Kentucky/2/1986 H3N8)

PB2_I86A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Equine/Prague/1/1956 H7N7)

PB2_I56A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Equine/Tennessee/5/1986 H3N8)

PA_I86A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Guinea fowl/Hong Kong/38/2002 H5N1 genotype X0)

PA_I02A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Gull/Astrakhan/227/1984 H13N6)

PB2_I84A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Hong Kong/212/2003 H5N1 genotype Z+)

PB2_I03A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Kiev/59/1979 H1N1)

PB2_I79A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Memphis/8/1988 H3N2)

PB2_I88A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Pintail/Alberta/119/1979 H4N6)

PA_I79A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Seal/Massachusetts/133/1982 H4N5)

PB2_I82A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Silky Chicken/Hong Kong/SF189/2001 H5N1 genotype A)

PA_I01A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Silky Chicken/Hong Kong/YU100/2002 H5N1 genotype X3)

PA_I02A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Swine/Hong Kong/126/1982 H3N2)

PA_I82A4 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Swine/Hong Kong/81/1978 H3N2)

PA_I78A9 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)

PB2_I77AC Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)

PA_I77AD Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Teal/China/2978.1/2002 H5N1 genotype W)

PB2_I02A7 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Turkey/Minnesota/501/1978 H6N8)

PA_I78AC Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza A virus (strain A/Turkey/Ontario/7732/1966 H5N9)

PB2_I66A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Vietnam/1203/2004 H5N1)

PA_I04A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 4E5E; 4E5F; 4E5G; 4E5H; 4E5I; 4E5J; 4E5L

1 entry

Influenza A virus (strain swl A/California/04/2009 H1N1)

PA_I09A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

pdb 4AVG; 4AVL; 4AVQ; 4AWF; 4AWG; 4AWH; 4AWK; 4AWM; 5CCY; 5CGV; 5CL0; 5CZN; 5D2O; 5D42; 5D4G; 5D8U; 5D9J; 5DBS; 5DEB; 5DES; 5EGA; 5VP8; 5VPT; 5VPX; 5VQN; 5VRJ; 5W3I; 5W44; 5W73; 5W7U; 5W92; 5W9G; 5WA6; 5WA7; 5WAP; 5WB3; 5WCS; 5WCT; 5WDC; 5WDN; 5WDW; 5WE7; 5WE9; 5WEB; 5WEF; 5WEI; 5WF3; 5WFM; 5WFW; 5WFZ; 5WG9; 6DCY; 6DCZ; 6DZQ; 6E0Q; 6E3M; 6E3N; 6E3O; 6E3P; 6E4C; 6E6V; 6E6W; 6E6X; 6FS6; 6FS7; 7K0W; 7LM4; 7ML8; 7MPF; 7MTY; 7MX0; 7MY5; 7N47; 7N55; 7N68; 7N8F; 7RKP; 7V04; 8CTF; 8DAL; 8DDB; 8DDE; 8DHN; 8DJV; 8DJY; 8T5V; 8T5W; 8T5Z; 8T67; 8T6Z; 8T81; 8T94; 8VGZ

1 entry

Influenza B virus (strain B/Singapore/222/1979)

PA_INBSI Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

1 entry

Influenza C virus (strain C/Berlin/1/1985)

PB2_INCBE Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Ippy mammarenavirus (isolate Rat/Central African Republic/Dak An B 188 d/1970) (IPPYV)

L_IPPYV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Junin mammarenavirus (JUNV) (Junn mammarenavirus)

L_JUNIN RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Machupo virus (MACV)

L_MACHU RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

pdb 7VGQ; 7VH1; 7VH2; 7VH3

1 entry

Mammarenavirus lassaense

L_LASV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

pdb 5IZH; 5J1N; 5J1P

1 entry

Mobala mammarenavirus (isolate Rat/Central African Republic/Acar 3080/1983) (MOBV)

L_MOBVC RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Puumala virus (strain Bank vole/Russia/CG1820/1984)

L_PUUMG RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

1 entry

Sabia mammarenavirus (isolate Human/Brasil/SPH114202/1990) (SABV) (Sabi mammarenavirus)

L_SABVB RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Seoul virus (strain 80-39)

L_SEOU8 RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

1 entry

Sin Nombre orthohantavirus (SNV) (Sin Nombre virus)

L_SINV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...

1 entry

Tamiami mammarenavirus (isolate Rat/United States/W 10777/1964) (TAMV)

L_TAMVU RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...

1 entry

Tula orthohantavirus (TULV) (Tula virus)

L_TULV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (RdRp) ...