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Viral enzymes are listed in fact sheets for each virus genus or family. This table shows all enzymatic activities of eukaryotic viruses and refers to the corresponding page, if available. (This page is under development):

Viral replication

Polymerase
Initiation
Elongation
Topology
  • DNA topoisomerase

  • DNA ligase

  • Helicase

  • Holliday junction resolvase

  • Integrase

  • Transposase (DDE recombinase),
Nucleotide metabolism
  • Thymidine kinase

  • Thymidylate synthase

  • dUTP diphosphatase

  • Dihydrofolate reductase

  • Ribonucleotide reductase

Regulation

  • E3 SUMO-protein ligase

Viral transcription

Transcriptase
Viral mRNA capping
PolyAdenylation
  • Poly(A) polymerase

  • RNA polymerase stuttering

Viral-Host modulation

Anti-viral evasion

  • Polyuridine endonuclease

  • Viral ADP-Ribosylhydrolase

  • Ser/Thr kinase

  • Tyr kinase

  • Ubiquitin transferase=Ubiquitin-conjugating enzyme E2
  • ubiquitinyl hydrolase
  • Tyr/ser/thr phosphatase
  • 2',3'-cGAMP endonuclease,
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
  • ADP-ribose hydrolase, >
Host shut off
  • mRNA-decapping

Protein modification

Proteases
Post translational modification
  • Beta-1,6-N-acetyl-glucosaminyl transferase

  • Peptide N-myristoyl transferase,
  • thiol oxidase

Exit

Budding
Virion release
Unclassified
  • Trans-prenyltransferase

  • Deoxyuridine 5'-triphosphate nucleotidohydrolase
  • Ribonucleoside-diphosphate reductase
  • FAD-linked sulfhydryl oxidase