Orthodiscovirus (taxid:2948850)

VIRION

Non-enveloped.

GENOME

Segmented Negative-stranded RNA linear genome, L segment is about 6.5 kb, M segment about 1.6 kb and S segment about 1.2 kb.
Encodes for at least three proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase (L) binds to a promoter on each encapsidated segment, and transcribes the mRNAs. These are capped by L protein during synthesis using cap snatching . Transcription is terminated by a strong hairpin sequence at the end of each gene.

ENZYMES

• RNA-dependent RNA polymerase [L]
• Cap Snatching endonuclease [L]

REPLICATION

CYTOPLASMIC

1. The ribonucleocapsids enters a cell by Fungal intercellular connetions
2. Transcription, viral mRNAs are capped in the cytoplasm.
3. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
4. The ribonucleocapsids is transmitted to another cell by Fungal intercellular connetions