Orthopoxvirus

VIRION

Enveloped, brick-shaped virion, 250nm long and 200nm wide. The surface membrane displays surface tubules or surface filaments. Two distinct infectious virus particles exists: the intracellular mature virus (IMV) and the extracellular enveloped virus (EEV).
Vaccinia virion 3D tour

GENOME

Linear, dsDNA genome of 170-250kb. The linear genome is flanked by inverted terminal repeat (ITR) sequences which form covalently closed hairpin termini at each extremity.
Vaccinia virus strain Western Reserve genome at Poxvirus Bioinformatics Resource center

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Attachement of the viral proteins to host glycosaminoglycans (GAGs) mediates endocytosis of the virus into the host cell. The virus can be uptaked also by apoptotic mimicry
  2. Fusion with the plasma membrane to release the core into the host cytoplasm.
  3. Early phase: early genes are transcribed in the cytoplasm by viral RNA polymerase. Early expression begins at 30 minutes post-infection.
  4. Core is completely uncoated as early expression ends, viral genome is now free in the cytoplasm.
  5. Intermediate phase: Intermediate genes are expressed, triggering genomic DNA replication at approximately 100 minutes post-infection.
  6. Late phase: Late genes are expressed from 140 min to 48 hours post-infection, producing all structural proteins.
  7. Assembly of progeny virions starts in cytoplasmic viral factories, producing an spherical immature particle. This virus particle matures into brick-shaped intracellular mature virion (IMV).
  8. IMV virion can be released upon cell lysis, or can acquire a second double membrane from trans-Golgi and bud as external enveloped virion (EEV).

Host-virus interaction

Adaptive immune response inhibition

The vaccinia virus A35R localizes to host endosomes and inhibits MHC class II antigen presentation .

Apoptosis modulation

Several poxviral proteins are dedicated to the inhibition of host apoptosis. Vaccinia F1L functions both as a suppressor of proapoptotic Bcl-2 family proteins and as an inhibitor of caspase-9 .

Autophagy modulation

Vaccinia virus actively disrupts the cellular autophagy through a mechanism that involves aberrant LC3 lipidation and a direct conjugation between ATG12 and ATG3 .

NF-kappa-B modulation

The B14 protein from vaccinia virus functions by binding to the IKK complex via an interaction with IKK-beta and preventing the phosphorylation of IKK-beta on its activation loop. In turn, IKK-beta is not activated and fails to phosphorylate IkB-beta, leaving IkB-beta able to retain NF-kappa-B in the cytoplasm .

Innate immune response inhibition

Poxviruses inhibit the cascade leading to production of interferon-beta by mainly targeting the host IRF3 protein. For instance, vaccinia virus protein C6 inhibits IRF3 activation downstream of TBK1 .

Matching UniProtKB/Swiss-Prot entries

922 entries grouped by strain (browse by keywords)

All proteins are shown (view only 798 complete proteome entries)

257 entries

Vaccinia virus (strain Copenhagen) (VACV) reference strain

Select_allDeselect_all
ATI3_VACCC 7 kDa A-type inclusion protein
B11_VACCC Protein B11
B6_VACCC Protein B6
B9_VACCC Protein B9
B17_VACCC Protein B17
B8_VACCC Soluble interferon gamma receptor B8 (B8)
B14_VACCC Protein B14 (Protein B15)
RP18_VACCC DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RUVV_VACCC Resolvase A22 (EC 3.1.-.-)
SANS_VACCC Surface antigen S (S antigen)
SEMA_VACCC Semaphorin-like protein A39
RP22_VACCC DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)
RP19_VACCC DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RP30_VACCC DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP35_VACCC DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP147_VACCC DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP07_VACCC DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP132_VACCC DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
PROF_VACCC Profilin
SODL_VACCC Cu-Zn superoxide dismutase-like protein
RIR1_VACCC Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large ...
RIR2_VACCC Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small ...
RAP94_VACCC RNA polymerase-associated transcription-specificity factor RAP94 (Protein H4) (RPO-associated ...
N1_VACCC Protein N1
N2_VACCC Protein N2
J5_VACCC Protein J5
KRB2_VACCC Probable serine/threonine-protein kinase B12 (EC 2.7.11.1)
KTHY_VACCC Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
PAP1_VACCC Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L) (VP55)
P4A_VACCC Major core protein 4a precursor (p4a) (Virion core protein 4a precursor) [Cleaved into: Core protein ...
MCEL_VACCC mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
MCE_VACCC Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57) (Poly(A) polymerase regulatory ...
M2_VACCC Protein M2
MCES_VACCC mRNA-capping enzyme regulatory subunit (Virus termination factor small subunit) (VTF small subunit) ...
NPH2_VACCC RNA helicase NPH-II (EC 3.6.4.13) (Nucleoside triphosphatase II) (NTPase II) (Nucleoside ...
L2_VACCC Protein L2
M1_VACCC Ankyrin repeat protein M1
KITH_VACCC Thymidine kinase (EC 2.7.1.21)
NTP1_VACCC Nucleoside triphosphatase I (EC 3.6.1.15) (Factor X) (NPH-I) (Nucleoside triphosphate ...
O1_VACCC Protein O1
O3_VACCC Protein O3
P4B_VACCC Major core protein 4b (Virion core protein 4b) (p4b)
L5_VACCC Protein L5
L1_VACCC Protein L1 (Virion membrane protein M25)
L3_VACCC Protein L3
A30_VACCC Protein A30
A34_VACCC Protein A34
A35_VACCC Protein A35
A38_VACCC Protein A38
A46_VACCC Protein A46
A51_VACCC Protein A51
A17_VACCC Virion membrane protein A17 precursor (23 kDa late protein) [Cleaved into: Mature 21 kDa protein ...
A19_VACCC Protein A19
A21_VACCC Virion membrane protein A21
A40_VACCC Protein A40
A41_VACCC Protein A41
A47_VACCC Protein A47
A4_VACCC 39kDa core protein (p39) (Protein A4)
B1_VACCC B1 kinase (Serine/threonine-protein kinase 1) (EC 2.7.11.1) (Vaccinia protein kinase 1)
B2_VACCC Protein B2
B3_VACCC Protein B3
D3_VACCC Core protein D3 (27 kDa virion core protein)
B4_VACCC Ankyrin repeat protein B4
B5_VACCC Plaque-size/host range protein (Protein B5)
B7_VACCC Protein B7
C8_VACCC Protein C8
C10_VACCC Protein C10
C13_VACCC Protein C13
C22L_VACCC Truncated CrmB protein
C4_VACCC Protein C4
C6_VACCC Protein C6
C9L_VACCC Ankyrin repeat protein C9L
CAHH_VACCC Cell surface-binding protein (Carbonic anhydrase homolog)
C5_VACCC Protein C5
C7_VACCC Interferon antagonist C7 (Host range protein 2)
D10_VACCC mRNA-decapping protein D10 (EC 3.1.3.-)
D13_VACCC Scaffold protein D13 (62 kDa protein) (Rifampicin resistance protein)
D9_VACCC mRNA-decapping protein D9 (EC 3.1.3.-)
D2_VACCC Core protein D2
D5_VACCC Primase D5 (EC 3.6.4.-)
DNLI_VACCC DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
DPOL_VACCC DNA polymerase (EC 2.7.7.7) [Includes: 3'-5' exodeoxyribonuclease (3'-5' exonuclease) (EC 3.1.11.-)]
DUSP_VACCC Dual specificity protein phosphatase H1 (EC 3.1.3.-) (EC 3.1.3.48) (Late protein H1)
C1_VACCC Protein C1
C20L_VACCC Uncharacterized protein C20L
C23L_VACCC Inactive chemokine-binding protein (vCKBP)
A18_VACCC Transcript termination protein A18 (EC 3.6.4.-) (56 kDa abortive late protein)
A31_VACCC Protein A31
A52_VACCC Protein A52
3BHS_VACCC 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (3-beta-HSD) [Includes: ...
A145_VACCC Virion membrane protein A14.5
A15_VACCC Core protein A15
A16_VACCC Virion membrane protein A16
A37_VACCC Protein A37
A43_VACCC Protein A43
A25_VACCC Protein A2.5
A27_VACCC 14 kDa fusion protein
A32_VACCC Protein A32
A36_VACCC Protein A36
A6_VACCC Protein A6
A11_VACCC Protein A11
A13_VACCC Protein A13 (Protein P8)
A14_VACCC Virion membrane protein A14
A20_VACCC DNA polymerase processivity factor component A20
A26_VACCC Putative A-type inclusion protein (ATI) (Protein A26)
A28_VACCC Envelope protein A28 homolog
A33_VACCC Protein A33
A53_VACCC Truncated secreted TNF-receptor-like protein A53
A57_VACCC Guanylate kinase homolog
A9_VACCC Virion membrane protein A9
A12_VACCC 25 kDa core protein A12L [Cleaved into: 17 kDa core protein A12L (17K)]
A49_VACCC Protein A49
GLRX1_VACCC Glutaredoxin-1
F9_VACCC Protein F9
G1_VACCC Metalloendopeptidase G1 (EC 3.4.24.-)
GLRX2_VACCC Glutaredoxin-2
H3_VACCC Envelope protein H3 (Ag35) (Virion envelope protein p35)
HEMA_VACCC Protein A56 (Hemagglutinin)
H2_VACCC Protein H2
H7_VACCC Late protein H7
F15_VACCC Protein F15
F1_VACCC Protein F1
F8_VACCC Protein F8
F14_VACCC Protein F14
F3_VACCC Kelch repeat protein F3
F5_VACCC 36 kDa major membrane protein F5
F6_VACCC Protein F6
F7_VACCC Protein F7
H5_VACCC Late transcription elongation factor H5 (Viral late gene transcription factor 4) (VLTF-4)
I1_VACCC Telomere-binding protein I1
I6_VACCC Telomere-binding protein I6
I2_VACCC Protein I2
I5_VACCC Protein I5
G3_VACCC Protein G3
G7_VACCC Assembly protein G7
G9_VACCC Myristoylated protein G9
G6_VACCC Uncharacterized protein G6
G2_VACCC Late transcription elongation factor G2 (Protein G2)
G5_VACCC Putative nuclease G5 (EC 3.1.-.-)
ETF1_VACCC Early transcription factor 70 kDa subunit (EC 3.6.4.-) (ATP-dependent helicase VETFS) (ETF small ...
F11_VACCC Protein F11
KBTB1_VACCC Kelch repeat and BTB domain-containing protein 1
K7_VACCC Protein K7
K1_VACCC Interferon antagonist K1L (32.5 kDa protein) (Host range protein 1)
K3_VACCC Protein K3
K5_VACCC Protein K5
K6_VACCC Protein K6
K4_VACCC Phospholipase-D-like protein K4
I3_VACCC Protein I3
I7_VACCC Core protease I7 (EC 3.4.22.-)
E10_VACCC Probable FAD-linked sulfhydryl oxidase E10 (EC 1.8.3.2)
E3_VACCC Protein E3 (p25)
F12_VACCC Protein F12
F13_VACCC Envelope protein F13 (37 kDa protein) (Palmitoylated EV membrane protein) (p37K)
F16_VACCC Protein F16
F17_VACCC Core phosphoprotein F17
DUT_VACCC Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
E11_VACCC Protein E11
E5_VACCC Protein E5
E6_VACCC Protein E6
E8_VACCC Protein E8
E7_VACCC Protein E7
ETF2_VACCC Early transcription factor 82 kDa subunit (ETF large subunit) (VETF A7 subunit) (Vaccinia virus ...
E2_VACCC Protein E2
J1_VACCC Protein J1
IL1BP_VACCC Interleukin-1-binding protein (Protein B16)
VB20_VACCC Protein B20
VC15_VACCC Protein C15/B21
VC17_VACCC Ankyrin repeat protein C17/B23
VPK2_VACCC Serine/threonine-protein kinase 2 (EC 2.7.11.1) (Vaccinia protein kinase 2)
VLTF1_VACCC Late transcription factor 1 (VLTF-1) (Trans-activator protein GK1)
VTF3S_VACCC Intermediate transcription factor 3 small subunit (VITF-3 32 kDa subunit) (VITF-3 small subunit)
SPI1_VACCC Serine proteinase inhibitor 1 (Serp-1) (Serpin-1)
SPI2A_VACCC Putative serine proteinase inhibitor 2 homolog first part
TOP1_VACCC DNA topoisomerase 1B (TopIB) (EC 5.99.1.2) (DNA topoisomerase I) (Late protein H6)
YVAI_VACCC Uncharacterized 8.2 kDa protein
YVAL_VACCC Uncharacterized 9.9 kDa protein
YVAN_VACCC Uncharacterized 7.9 kDa protein
YVAP_VACCC Uncharacterized 9.9 kDa protein
YVD1_VACCC Uncharacterized 7.0 kDa protein
YVDG_VACCC Uncharacterized 10.4 kDa protein
YVDI_VACCC Uncharacterized 9.5 kDa protein
YVEA_VACCC Uncharacterized 7.6 kDa protein
YVEE_VACCC Uncharacterized 7.6 kDa protein
YVAU_VACCC Uncharacterized 8.8 kDa protein
YVBB_VACCC Uncharacterized 7.9 kDa protein
YVBF_VACCC Uncharacterized 8.4 kDa protein
YVBG_VACCC Uncharacterized 11.2 kDa protein
YVCB_VACCC Uncharacterized 8.4 kDa protein
YVDA_VACCC Uncharacterized 9.2 kDa protein
YVFE_VACCC Uncharacterized 7.8 kDa protein
YVGB_VACCC Uncharacterized 8.4 kDa protein
YVHA_VACCC Uncharacterized 8.1 kDa protein
YVDB_VACCC Uncharacterized 8.5 kDa protein
YVDD_VACCC Uncharacterized 7.9 kDa protein
YVDE_VACCC Uncharacterized 9.3 kDa protein
YVAA_VACCC Uncharacterized 14.1 kDa protein
YVAB_VACCC Uncharacterized 10.7 kDa protein
YVAG_VACCC Uncharacterized 9.3 kDa protein
YVAK_VACCC Uncharacterized 7.5 kDa protein
YVAR_VACCC Uncharacterized 8.5 kDa protein
YVCD_VACCC Uncharacterized 7.9 kDa protein
YVDF_VACCC Uncharacterized 7.7 kDa protein
YVDH_VACCC Uncharacterized 7.2 kDa protein
YVKA_VACCC Uncharacterized 9.4 kDa protein
YVKB_VACCC Uncharacterized 9.0 kDa protein
VC19_VACCC Protein C19/B25
VC16_VACCC Protein C16/B22
VC18_VACCC Ankyrin repeat protein C18/B24
VC02_VACCC Kelch repeat protein C2
VB10_VACCC Kelch repeat protein B10
VC21_VACCC Protein C21/B27
VCP_VACCC Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP)
VB18_VACCC Ankyrin repeat protein B18
VGF_VACCC Pro-vaccinia growth factor (Pro-VGF) [Cleaved into: Vaccinia growth factor (VGF) (Secreted epidermal ...
VC14_VACCC Protein C14
VA54_VACCC Protein A54
VLTF2_VACCC Viral late gene transcription factor 2 (VLTF-2) (Trans-activator protein A1)
SPI2B_VACCC Putative serine proteinase inhibitor 2 homolog second part
SPI3_VACCC Protein K2 (Serine proteinase inhibitor 3)
UNG_VACCC Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)
VP8_VACCC Core protein VP8 (25 kDa major core protein) (L4 core protein) (P25K)
VITF3_VACCC Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)
VLTF3_VACCC Viral late gene transcription factor 3 (VLTF-3) (Trans-activator protein A2)
YVFD_VACCC Uncharacterized 9.9 kDa protein
YVAH_VACCC Uncharacterized 14.5 kDa protein
YVAJ_VACCC Uncharacterized 7.9 kDa protein
YVBA_VACCC Uncharacterized 11.8 kDa protein
YVBD_VACCC Uncharacterized 7.8 kDa protein
YVED_VACCC Uncharacterized 7.6 kDa protein
YVFB_VACCC Uncharacterized 8.3 kDa protein
YVFF_VACCC Uncharacterized 8.8 kDa protein
YVGA_VACCC Uncharacterized 14.3 kDa protein
YVAM_VACCC Uncharacterized 8.6 kDa protein
YVAO_VACCC Uncharacterized 9.5 kDa protein
YVAQ_VACCC Uncharacterized 8.6 kDa protein
YVAS_VACCC Uncharacterized 7.5 kDa protein
YVAT_VACCC Uncharacterized 8.9 kDa protein
YVBC_VACCC Uncharacterized 10.8 kDa protein
YVBE_VACCC Uncharacterized 10.5 kDa protein
YVBH_VACCC Uncharacterized 7.4 kDa protein
YVBI_VACCC Uncharacterized 7.6 kDa protein
YVCA_VACCC Uncharacterized 8.0 kDa protein
YVD2_VACCC Uncharacterized 8.6 kDa protein
YVEB_VACCC Uncharacterized 11.9 kDa protein
YVFC_VACCC Uncharacterized 11.6 kDa protein
YVIA_VACCC Uncharacterized 9.3 kDa protein
YVAC_VACCC Uncharacterized 14.4 kDa protein
YVAD_VACCC Uncharacterized 9.8 kDa protein
YVAE_VACCC Uncharacterized 18.2 kDa protein
YVAF_VACCC Uncharacterized 8.4 kDa protein
YVCC_VACCC Uncharacterized 9.2 kDa protein
YVCE_VACCC Uncharacterized 7.2 kDa protein
YVDC_VACCC Uncharacterized 7.3 kDa protein
YVEC_VACCC Uncharacterized 8.0 kDa protein
YVEF_VACCC Uncharacterized 12.9 kDa protein
YVFA_VACCC Uncharacterized 7.1 kDa protein

217 entries

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

Select_allDeselect_all
ATI3_VACCW 7 kDa A-type inclusion protein
B2_VACCW Protein B2
B5_VACCW Plaque-size/host range protein (Protein B5)
B8_VACCW Soluble interferon gamma receptor B8 (B8)
B19_VACCW Ankyrin repeat protein B19
B4_VACCW Ankyrin repeat protein B4
B10_VACCW Kelch repeat protein B10
ATI2_VACCW 17 kDa A-type inclusion protein
B14_VACCW Protein B14
B25_VACCW Truncated ankyrin repeat protein B25
ATI4_VACCW 27 kDa A-type inclusion protein
B1_VACCW B1 kinase (Serine/threonine-protein kinase 1) (EC 2.7.11.1) (Vaccinia protein kinase 1)
B9_VACCW Protein B9
RP147_VACCW DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP19_VACCW DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RP35_VACCW DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
PROF_VACCW Profilin
SEMA_VACCW Semaphorin-like protein A39
RIR2_VACCW Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small ...
RP132_VACCW DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
RP18_VACCW DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RP30_VACCW DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP07_VACCW DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP22_VACCW DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)
RUVV_VACCW Resolvase A22 (EC 3.1.-.-) (DNA holliday junction resolvase A22)
RAP94_VACCW RNA polymerase-associated transcription-specificity factor RAP94 (Protein H4) (RPO-associated ...
RIR1_VACCW Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large ...
SEMA2_VACCW Semaphorin-like protein VACWR164
SPI2_VACCW Serine proteinase inhibitor 2 (Serp-2) (Serpin-2)
SODL_VACCW Cu-Zn superoxide dismutase-like protein A45R
N2_VACCW Protein N2
N1_VACCW Protein N1
K4_VACCW Phospholipase-D-like protein K4 (Protein K3)
K7_VACCW Protein K7
L1_VACCW Protein L1 (Virion membrane protein M25)
L3_VACCW Protein L3 (Protein F4)
KTHY_VACCW Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
O3_VACCW Protein O3
KBTB1_VACCW Kelch repeat and BTB domain-containing protein A55
P4B_VACCW Major core protein 4b (Virion core protein 4b) (p4b)
PAP1_VACCW Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L) (VP55)
P28_VACCW Truncated p28 protein
P4A_VACCW Major core protein 4a precursor (p4a) (Virion core protein 4a precursor) [Cleaved into: Core protein ...
MCE_VACCW Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57) (Poly(A) polymerase regulatory ...
MCEL_VACCW mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
M2_VACCW Protein M2
NPH2_VACCW RNA helicase NPH-II (EC 3.6.4.13) (Nucleoside triphosphatase II) (NTPase II) (Nucleoside ...
M1_VACCW Ankyrin repeat protein M1
MCES_VACCW mRNA-capping enzyme regulatory subunit (Virus termination factor small subunit) (VTF small subunit) ...
KITH_VACCW Thymidine kinase (EC 2.7.1.21)
NTP1_VACCW Nucleoside triphosphatase I (EC 3.6.1.15) (Factor X) (NPH-I) (Nucleoside triphosphate ...
O1_VACCW Protein O1
P28B_VACCW Zinc finger-containing protein P28b
KRB2_VACCW Probable serine/threonine-protein kinase B12 (EC 2.7.11.1)
L2_VACCW Protein L2 (Protein F3)
L5_VACCW Protein L5 (Protein F6)
A31_VACCW Protein A31
A11_VACCW Protein A11
A13_VACCW Virion membrane protein A13 (Protein P8)
A145_VACCW Virion membrane protein A14.5
A15_VACCW Core protein A15
A37_VACCW Protein A37
A43_VACCW Protein A43
A4_VACCW 39kDa core protein (p39) (Protein A4)
A51_VACCW Protein A51
B11_VACCW Protein B11
B18_VACCW Soluble interferon alpha/beta receptor B18 (B18)
D3_VACCW Core protein D3 (27 kDa virion core protein)
B3_VACCW Protein B3
B6_VACCW Protein B6
B7_VACCW Protein B7
B17_VACCW Protein B17
B21_VACCW Uncharacterized protein B21
C4_VACCW Protein C4
C22L_VACCW Truncated CrmB protein
C7_VACCW Interferon antagonist C7 (Host range protein 2)
C8_VACCW Protein C8
C1_VACCW Protein C1
C6_VACCW Protein C6
C9L_VACCW Ankyrin repeat protein C9L
D2_VACCW Core protein D2
D10_VACCW mRNA-decapping protein D10 (EC 3.1.3.-)
D5_VACCW Primase D5 (EC 3.6.4.-)
D13_VACCW Scaffold protein D13 (62 kDa protein) (Rifampicin resistance protein)
D9_VACCW mRNA-decapping protein D9 (EC 3.1.3.-)
DPOL_VACCW DNA polymerase (EC 2.7.7.7) [Includes: 3'-5' exodeoxyribonuclease (3'-5' exonuclease) (EC 3.1.11.-)]
DUT_VACCW Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
DNLI_VACCW DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
C10_VACCW Protein C10
C13_VACCW Protein C13 (Protein B23R)
C20L_VACCW Uncharacterized protein C20L
CAHH_VACCW Cell surface-binding protein (Carbonic anhydrase homolog)
C23L_VACCW Inactive chemokine-binding protein (vCKBP)
C2_VACCW Kelch repeat protein C2
C5_VACCW Protein C5
3BHS_VACCW 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (3-beta-HSD) [Includes: ...
A19_VACCW Protein A19
A375_VACCW Uncharacterized protein A37.5
A53R_VACCW Truncated secreted TNF-receptor-like protein A53R
A9_VACCW Virion membrane protein A9
A12_VACCW 25 kDa core protein A12L [Cleaved into: 17 kDa core protein A12L (17K)]
A14_VACCW Virion membrane protein A14
A20_VACCW DNA polymerase processivity factor component A20
A25_VACCW Protein A2.5
A32_VACCW Protein A32
A36_VACCW Protein A36
A40_VACCW Protein A40
A49_VACCW Protein A49R
A6_VACCW Protein A6
169_VACCW Protein 169
A27_VACCW Protein A27
A305_VACCW Uncharacterized protein A30.5
A33_VACCW Protein A33
A46_VACCW Protein A46
A565_VACCW Uncharacterized protein A56.5
A57_VACCW Guanylate kinase homolog
A16_VACCW Virion membrane protein A16
A17_VACCW Virion membrane protein A17 precursor (23 kDa late protein) [Cleaved into: Mature 21 kDa protein ...
A18_VACCW Transcript termination protein A18 (EC 3.6.4.-) (56 kDa abortive late protein)
A21_VACCW Virion membrane protein A21
A26_VACCW Protein A26
A28_VACCW Envelope protein A28
A30_VACCW Protein A30
A34_VACCW Protein A34
A35_VACCW Protein A35
A52_VACCW Protein A52
A38_VACCW Protein A38
A41_VACCW Protein A41
A47_VACCW Protein A47
F9_VACCW Protein F9
GLRX1_VACCW Glutaredoxin-1
G3_VACCW Protein G3
GLRX2_VACCW Glutaredoxin-2
H3_VACCW Envelope protein H3 (Ag35) (Virion envelope protein p35)
HEMA_VACCW Protein A56 (Hemagglutinin)
H5_VACCW Late transcription elongation factor H5 (Viral late gene transcription factor 4) (VLTF-4)
H2_VACCW Protein H2
H7_VACCW Late protein H7 (Protein H8)
F11_VACCW Protein F11
F13_VACCW Envelope protein F13 (37 kDa protein) (Palmitoylated EV membrane protein) (p37K)
F1_VACCW Protein F1
E5_VACCW Protein E5
E7_VACCW Protein E7
F16_VACCW Protein F16
F14_VACCW Protein F14
E11_VACCW Core protein E11
E2_VACCW Protein E2
F5_VACCW 36 kDa major membrane protein F5
F3_VACCW Kelch repeat protein F3
F7_VACCW Protein F7
I5_VACCW Protein I5 (Protein VP13K)
I2_VACCW Protein I2
I6_VACCW Telomere-binding protein I6
I7_VACCW Core protease I7 (EC 3.4.22.-)
I1_VACCW Telomere-binding protein I1
I3_VACCW Protein I3
G9_VACCW Myristoylated protein G9 (Protein F1)
G1_VACCW Metalloendopeptidase G1 (EC 3.4.24.-)
G2_VACCW Late transcription elongation factor G2 (Protein G2)
G5_VACCW Putative nuclease G5 (EC 3.1.-.-)
G6_VACCW Uncharacterized protein G6
G7_VACCW Assembly protein G7
ETF1_VACCW Early transcription factor 70 kDa subunit (EC 3.6.4.-) (ATP-dependent helicase VETFS) (ETF small ...
ETF2_VACCW Early transcription factor 82 kDa subunit (ETF large subunit) (VETF A7 subunit) (Vaccinia virus ...
F8_VACCW Protein F8
E8_VACCW Protein E8
K3_VACCW Protein K3 (Protein K2)
K1_VACCW Interferon antagonist K1L (32.5 kDa protein) (Host range protein 1)
J1_VACCW Protein J1 (Protein F7)
K5_VACCW Protein K5
K6_VACCW Protein K6
E3_VACCW Protein E3 (p25)
F17_VACCW Core phosphoprotein F17
F6_VACCW Protein F6
F12_VACCW Protein F12
F15_VACCW Protein F15
DUSP_VACCW Dual specificity protein phosphatase H1 (EC 3.1.3.-) (EC 3.1.3.48) (Late protein H1)
E6_VACCW Protein E6
E10_VACCW Probable FAD-linked sulfhydryl oxidase E10 (EC 1.8.3.2)
J5_VACCW Protein J5 (Protein F11)
IL1BP_VACCW Interleukin-1-binding protein (Protein B15)
IL18B_VACCW Interleukin-18-binding protein (vIL-18BP)
VLTF2_VACCW Viral late gene transcription factor 2 (VLTF-2) (Trans-activator protein A1)
VP8_VACCW Core protein VP8 (25 kDa major core protein) (F5 polypeptide) (L4 core protein) (P25K)
V2045_VACCW Uncharacterized protein VACWR204.5
VTF3S_VACCW Intermediate transcription factor 3 small subunit (VITF-3 32 kDa subunit) (VITF-3 small subunit)
VPK2_VACCW Serine/threonine-protein kinase 2 (EC 2.7.11.1) (Vaccinia protein kinase 2)
SPI3_VACCW Protein K2 (Serine proteinase inhibitor 3)
SPI1_VACCW Serine proteinase inhibitor 1 (Serp-1) (Serpin-1)
TCRM_VACCW Truncated Cytokine response-modifying protein B
TOP1_VACCW DNA topoisomerase 1B (TopIB) (EC 5.99.1.2) (DNA topoisomerase I) (Late protein H6)
YVBA_VACCW Uncharacterized 11.8 kDa protein
YVAM_VACCW Uncharacterized 8.6 kDa protein
YVAS_VACCW Uncharacterized 7.5 kDa protein
YVBD_VACCW Uncharacterized 7.8 kDa protein
YVAT_VACCW Uncharacterized 8.9 kDa protein
VGF_VACCW Pro-vaccinia growth factor (Pro-VGF) [Cleaved into: Vaccinia growth factor (VGF) (Secreted epidermal ...
VLTF1_VACCW Late transcription factor 1 (VLTF-1) (Trans-activator protein GK1)
V14_VACCW Ankyrin repeat protein 14
VA005_VACCW Uncharacterized protein VACWR005
V017_VACCW Uncharacterized protein 17
V018_VACCW Uncharacterized protein 18
VA006_VACCW Uncharacterized protein VACWR006
VA203_VACCW Ankyrin repeat protein VACWR203
VCP_VACCW Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP)
V016_VACCW Uncharacterized protein 16
VA201_VACCW Uncharacterized protein VACWR201
VITF3_VACCW Intermediate transcription factor 3 large subunit (VITF-3)
VA202_VACCW Uncharacterized protein VACWR202
VA003_VACCW Uncharacterized protein VACWR003
UNG_VACCW Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)
Y15_VACCW Uncharacterized protein 15
VLTF3_VACCW Viral late gene transcription factor 3 (VLTF-3) (Trans-activator protein A2)
Y36_VACCW Uncharacterized protein 36
YVAL_VACCW Uncharacterized 9.9 kDa protein
YVBE_VACCW Uncharacterized 10.5 kDa protein
ATI_VACCW A-type inclusion protein A25 (ATI)

159 entries

Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain

Select_allDeselect_all
B14_VAR67 Protein B14
B1_VAR67 B1 kinase (Serine/threonine-protein kinase 1) (EC 2.7.11.1) (Vaccinia protein kinase 1)
ATI_VAR67 A-type inclusion protein A25 homolog (ATI)
RP07_VAR67 DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP22_VAR67 DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)
RP18_VAR67 DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
SANS_VAR67 Surface antigen S (S antigen)
SEMA_VAR67 Semaphorin-like protein A43
RP19_VAR67 DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RP30_VAR67 DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP147_VAR67 DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP132_VAR67 DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
RP35_VAR67 DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RUVV_VAR67 Resolvase A22 (EC 3.1.-.-)
PROF_VAR67 Profilin
SPI1_VAR67 Serine proteinase inhibitor 1 (Serp-1) (Serpin-1)
SODL_VAR67 Cu-Zn superoxide dismutase-like protein
RIR1_VAR67 Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large ...
RIR2_VAR67 Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small ...
N2_VAR67 Protein N2
KTHY_VAR67 Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
O1_VAR67 Protein O1
PAP1_VAR67 Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L) (VP55)
P4A_VAR67 Major core protein 4a precursor (p4a) (Virion core protein 4a precursor) [Cleaved into: Core protein ...
P28_VAR67 E3 ubiquitin-protein ligase p28-like (EC 2.3.2.27) (D4R protein) (RING-type E3 ubiquitin transferase ...
P4B_VAR67 Major core protein 4b (Virion core protein 4b) (p4b)
M1_VAR67 Ankyrin repeat protein M1
MCES_VAR67 mRNA-capping enzyme regulatory subunit (Virus termination factor small subunit) (VTF small subunit) ...
N1_VAR67 Protein N1
NPH2_VAR67 RNA helicase NPH-II (EC 3.6.4.13) (Nucleoside triphosphatase II) (NTPase II) (Nucleoside ...
M2_VAR67 Protein M2
MCEL_VAR67 mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
L2_VAR67 Protein L2
L3_VAR67 Protein L3
L5_VAR67 Protein L5
MCE_VAR67 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57) (Poly(A) polymerase regulatory ...
KITH_VAR67 Thymidine kinase (EC 2.7.1.21)
NTP1_VAR67 Nucleoside triphosphatase I (EC 3.6.1.15) (NPH-I) (Nucleoside triphosphate phosphohydrolase I) (NPH ...
O3_VAR67 Protein O3
L1_VAR67 Protein L1 (Virion membrane protein M25)
RAP94_VAR67 RNA polymerase-associated transcription-specificity factor RAP94 (Protein H4) (RPO-associated ...
A18_VAR67 Transcript termination protein A18 (EC 3.6.4.-) (56 kDa abortive late protein)
A30_VAR67 Protein A30 (Protein A33)
A34_VAR67 Protein A34
A35_VAR67 Truncated protein A35 homolog
A38_VAR67 Protein A38
A41_VAR67 Protein A41
A43_VAR67 Protein A43
A14_VAR67 Virion membrane protein A14
A19_VAR67 Protein A19
A375_VAR67 Protein A37.5 homolog
A40_VAR67 Protein A40 homolog
CRMB_VAR67 Cytokine response-modifying protein B (CrmB) (Viral tumor necrosis factor receptor II) (vTNFR)
B17_VAR67 Protein B17
C6_VAR67 Protein C6
CAHH_VAR67 Cell surface-binding protein (Carbonic anhydrase homolog)
C10_VAR67 Protein C10
C23L_VAR67 Chemokine-binding protein (vCKBP) (35 kDa protein)
D13_VAR67 Scaffold protein D13 (62 kDa protein) (Rifampicin resistance protein)
D2_VAR67 Core protein D2
D10_VAR67 mRNA-decapping protein D10 (EC 3.1.3.-)
D5_VAR67 Primase D5 (EC 3.6.4.-)
D9_VAR67 mRNA-decapping protein D9 (EC 3.1.3.-)
D3_VAR67 Core protein D3 (27 kDa virion core protein)
DNLI_VAR67 DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
DUSP_VAR67 Dual specificity protein phosphatase H1 (EC 3.1.3.-) (EC 3.1.3.48) (Late protein H1)
DPOL_VAR67 DNA polymerase (EC 2.7.7.7) [Includes: 3'-5' exodeoxyribonuclease (3'-5' exonuclease) (EC 3.1.11.-)]
E6_VAR67 Protein E6
C5_VAR67 Protein C5
C1_VAR67 Protein C1
C4_VAR67 Protein C4
C7_VAR67 truncated interferon antagonist D8 (Host range protein 2)
C1L_VAR67 Truncated interferon antagonist C1L
A46_VAR67 Protein A46
3BHST_VAR67 Truncated 3-beta hydroxy-5-ene steroid dehydrogenase homolog
A145_VAR67 Virion membrane protein A14.5
A26_VAR67 Protein A26 homolog
A27_VAR67 14 kDa fusion protein
A47_VAR67 Protein A47
A16_VAR67 Virion membrane protein A16
A20_VAR67 DNA polymerase processivity factor component A20
A21_VAR67 Virion membrane protein A21
A25_VAR67 Protein A2.5
A28_VAR67 Envelope protein A28 homolog (Protein A31)
A32_VAR67 Protein A32
A36_VAR67 Protein A36
A4_VAR67 39kDa core protein (p39) (Protein A4)
A6_VAR67 Protein A6
A11_VAR67 Protein A11
A13_VAR67 Virion membrane protein A13
A15_VAR67 Core protein A15
A31_VAR67 Protein A31
A33_VAR67 Protein A33
A51_VAR67 Protein A51
3BHS_VAR67 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (3-beta-HSD) [Includes: ...
A12_VAR67 25 kDa core protein A12L [Cleaved into: 17 kDa core protein A12L (17K)]
A17_VAR67 Virion membrane protein A17 precursor (23 kDa late protein) [Cleaved into: Mature 21 kDa protein ...
A37_VAR67 Protein A37 homolog
A49_VAR67 Protein A49
A9_VAR67 Virion membrane protein A9
GLRX1_VAR67 Glutaredoxin-1
GLRX2_VAR67 Glutaredoxin-2
G1_VAR67 Metalloendopeptidase G1 (EC 3.4.24.-)
H2_VAR67 Late protein H2
H3_VAR67 Envelope protein H3 (Ag35) (Virion envelope protein p35)
H7_VAR67 Late protein H7
HEMA_VAR67 Protein A56 (Hemagglutinin)
H5_VAR67 Late transcription elongation factor H5 (Viral late gene transcription factor 4) (VLTF-4)
ETF2_VAR67 Early transcription factor 82 kDa subunit (ETF large subunit) (VETF A7 subunit)
F7_VAR67 Protein F7
E3_VAR67 Protein E3
F17_VAR67 Core phosphoprotein F17
F8_VAR67 Protein F8
F15_VAR67 Protein F15
F14_VAR67 Protein F14
F6_VAR67 Protein F6
F5_VAR67 36 kDa major membrane protein F5
F9_VAR67 Protein F9
I3_VAR67 Protein I3
I6_VAR67 Telomere-binding protein I6
I1_VAR67 Telomere-binding protein I1
G2_VAR67 Late transcription elongation factor G2 (Protein G2)
G6_VAR67 Uncharacterized protein G6
G3R_VAR67 Ankyrin repeat protein G3R
G3_VAR67 Protein G3
G9_VAR67 Myristoylated protein G9
G7_VAR67 Assembly protein G7
G5_VAR67 Putative nuclease G5 (EC 3.1.-.-)
F11_VAR67 Protein F11
F12_VAR67 Protein F12
F13_VAR67 Envelope protein F13 (37 kDa protein) (Palmitoylated EV membrane protein) (p37K)
DUT_VAR67 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
I5_VAR67 Protein I5
I7_VAR67 Core protease I7 (EC 3.4.22.-)
E11_VAR67 Protein E11
F16_VAR67 Protein F16
E5_VAR67 Protein E5
E10_VAR67 Probable FAD-linked sulfhydryl oxidase E10 (EC 1.8.3.2)
E7_VAR67 Protein E7
ETF1_VAR67 Early transcription factor 70 kDa subunit (EC 3.6.4.-) (ATP-dependent helicase VETFS) (ETF small ...
E2_VAR67 Protein E2
E8_VAR67 Protein E8
J1_VAR67 Protein J1
J5_VAR67 Protein J5
I2_VAR67 Protein I2
VGF_VAR67 Pro-variola growth factor (Pro-VGF) [Cleaved into: Variola growth factor (VGF) (Secreted epidermal ...
VTF3S_VAR67 Intermediate transcription factor 3 small subunit (VITF-3 32 kDa subunit) (VITF-3 small subunit)
VLTF2_VAR67 Viral late gene transcription factor 2 (VLTF-2) (Trans-activator protein A1)
VLTF3_VAR67 Viral late gene transcription factor 3 (VLTF-3) (Trans-activator protein A2)
VP8_VAR67 Core protein VP8 (25 kDa major core protein) (L4 core protein) (P25K)
VITF3_VAR67 Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)
SPI2_VAR67 Serine proteinase inhibitor 2 (Serp-2) (Serpin-2)
SPI3_VAR67 Protein K2 (Serine proteinase inhibitor 3)
TOP1_VAR67 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)
VB18_VAR67 Ankyrin repeat protein B18
VB04_VAR67 Ankyrin repeat protein B4
VPK2_VAR67 Serine/threonine-protein kinase 2 (EC 2.7.11.1)
UNG_VAR67 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)
VLTF1_VAR67 Late transcription factor 1 (VLTF-1) (Trans-activator protein GK1)

1 entry

Vaccinia virus (strain Ankara) (VACV) reference strain

CAHH_VACCA Cell surface-binding protein (Carbonic anhydrase homolog)

13 entries

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))

Select_allDeselect_all
YVD2_VACCW Uncharacterized 8.6 kDa protein
VA54_VACCW Protein A54
Y7K5_VACCW Uncharacterized 7.5 kDa protein
Y7K4_VACCW Uncharacterized 7.4 kDa protein
YVD1_VACCW Uncharacterized 7.0 kDa protein
YVDF_VACCW Uncharacterized 7.7 kDa protein
YVDA_VACCW Uncharacterized 9.2 kDa protein
YVDC_VACCW Uncharacterized 7.3 kDa protein
YVDD_VACCW Uncharacterized 7.9 kDa protein
YVDH_VACCW Uncharacterized 7.2 kDa protein
YVDB_VACCW Uncharacterized 8.5 kDa protein
YVDE_VACCW Uncharacterized 9.3 kDa protein
YVDG_VACCW Uncharacterized 10.4 kDa protein

80 entries

Vaccinia virus (strain Ankara) (VACV)

Select_allDeselect_all
B1_VACCA B1 kinase (Serine/threonine-protein kinase 1) (EC 2.7.11.1)
RP35_VACCA DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP07_VACCA DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP19_VACCA DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
PROF_VACCA Profilin
RUVV_VACCA Holliday junction resolvase (EC 3.1.-.-)
RP132_VACCA DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
RP147_VACCA DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP18_VACCA DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RPO5_VACCA DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RIR1_VACCA Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large ...
RIR2_VACCA Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small ...
SODL_VACCA Cu-Zn superoxide dismutase-like protein
SPI3_VACCA Protein K2 (Serine proteinase inhibitor 3)
LR_VACCA Protein L2
GLRX2_VACCA Glutaredoxin-2
L1_VACCA Protein L1 (Virion membrane protein M25)
PAP1_VACCA Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L) (VP55)
MP44_VACCA Metalloendopeptidase G1 (EC 3.4.24.-)
MCES_VACCA mRNA-capping enzyme regulatory subunit (Virus termination factor small subunit) (VTF small subunit) ...
NPH2_VACCA RNA helicase NPH-II (EC 3.6.4.13) (Nucleoside triphosphatase II) (NTPase II) (Nucleoside ...
MCEL_VACCA mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
MCE_VACCA Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57) (Poly(A) polymerase regulatory ...
L5_VACCA Protein L5
NTP1_VACCA Nucleoside triphosphatase I (EC 3.6.1.15) (Factor X) (Nucleoside triphosphate phosphohydrolase I) ...
KRB2_VACCA Probable serine/threonine-protein kinase B12 (EC 2.7.11.1)
KITH_VACCA Thymidine kinase (EC 2.7.1.21)
KTHY_VACCA Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
RAP94_VACCA RNA polymerase-associated transcription-specificity factor RAP94 (Protein H4) (RPO-associated ...
A11_VACCA Protein A11
A20_VACCA DNA polymerase processivity factor component A20
A49_VACCA Protein A49
A51_VACCA Protein A51
C10_VACCA Protein C10
D13_VACCA Scaffold protein D13 (62 kDa protein) (Rifampicin resistance protein)
D3_VACCA Core protein D3 (27 kDa virion core protein)
DNLI_VACCA DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
DPOL_VACCA DNA polymerase (EC 2.7.7.7) [Includes: 3'-5' exodeoxyribonuclease (3'-5' exonuclease) (EC 3.1.11.-)]
DUT_VACCA Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
C7_VACCA Interferon antagonist C7 (Host range protein 2)
A12_VACCA 25 kDa core protein A12L [Cleaved into: 17 kDa core protein A12L (17K)]
A21_VACCA Virion membrane protein A21
A47_VACCA Protein A47
A28_VACCA Envelope protein A28 homolog
A15_VACCA Core protein A15
A16_VACCA Virion membrane protein A16
3BHS_VACCA 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (3-beta-HSD) [Includes: ...
A18_VACCA Transcript termination protein A18 (EC 3.6.4.-) (56 kDa abortive late protein)
A19_VACCA Protein A19
A9_VACCA Virion membrane protein A9
GLRX1_VACCA Glutaredoxin-1
HEMA_VACCA Protein A56 (Hemagglutinin)
H7_VACCA Late protein H7
H2_VACCA Late protein H2
F12_VACCA Protein F12
ETF1_VACCA Early transcription factor 70 kDa subunit (EC 3.6.4.-) (ATP-dependent helicase VETFS) (ETF small ...
F3_VACCA Kelch repeat protein F3
F6_VACCA Protein F6
I1_VACCA Telomere-binding protein I1
G9_VACCA Myristoylated protein G9
G7_VACCA Assembly protein G7
F13_VACCA Envelope protein F13 (37 kDa protein) (Palmitoylated EV membrane protein) (p37K)
F14_VACCA Protein F14
F1_VACCA Protein F1
J5_VACCA Protein J5
K7_VACCA Protein K7
ETF2_VACCA Early transcription factor 82 kDa subunit (ETF large subunit) (VETF A7 subunit) (Vaccinia virus ...
IL1BP_VACCA Interleukin-1-binding protein (Protein B16)
VLTF1_VACCA Late transcription factor 1 (VLTF-1) (Trans-activator protein GK1)
VLTF2_VACCA Viral late gene transcription factor 2 (VLTF-2) (Trans-activator protein A1)
VB05_VACCA Plaque-size/host range protein (Protein B5)
VGF_VACCA Pro-vaccinia growth factor (Pro-VGF) [Cleaved into: Vaccinia growth factor (VGF) (Secreted epidermal ...
VTF3L_VACCA Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)
VTF3S_VACCA Intermediate transcription factor 3 small subunit (VITF-3 32 kDa subunit) (VITF-3 small subunit)
TOP1_VACCA DNA topoisomerase 1B (TopIB) (EC 5.99.1.2) (DNA topoisomerase I) (Late protein H6)
VPK2_VACCA Serine/threonine-protein kinase 2 (EC 2.7.11.1) (Vaccinia protein kinase 2)
VB10_VACCA Kelch repeat protein B10
VB18_VACCA Ankyrin repeat protein B18
VLTF3_VACCA Viral late gene transcription factor 3 (VLTF-3) (Trans-activator protein A2)
UNG_VACCA Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)

33 entries

Vaccinia virus (strain Tian Tan) (VACV)

Select_allDeselect_all
RP07_VACCT DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP35_VACCT DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP132_VACCT DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
PROF_VACCT Profilin
SODL_VACCT Cu-Zn superoxide dismutase-like protein
KITH_VACCT Thymidine kinase (EC 2.7.1.21)
KTHY_VACCT Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
PAP1_VACCT Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L) (VP55)
MCEL_VACCT mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
NPH2_VACCT RNA helicase NPH-II (EC 3.6.4.13) (Nucleoside triphosphatase II) (NTPase II) (Nucleoside ...
MP44_VACCT Metalloendopeptidase G1 (EC 3.4.24.-)
D3_VACCT Core protein D3 (27 kDa virion core protein)
CAHH_VACCT Cell surface-binding protein (Carbonic anhydrase homolog)
D13_VACCT Scaffold protein D13 (62 kDa protein) (Rifampicin resistance protein)
A16_VACCT Virion membrane protein A16
A18_VACCT Transcript termination protein A18 (EC 3.6.4.-) (56 kDa abortive late protein)
GLRX1_VACCT Glutaredoxin-1
GLRX2_VACCT Glutaredoxin-2
H7_VACCT Late protein H7
HEMA_VACCT Protein A56 (Hemagglutinin)
F1_VACCT Protein F1
I1_VACCT Telomere-binding protein I1
G3_VACCT Protein G3
G9_VACCT Myristoylated protein G9
ETF2_VACCT Early transcription factor 82 kDa subunit (ETF large subunit) (VETF A7 subunit) (Vaccinia virus ...
F17_VACCT Core phosphoprotein F17
ETF1_VACCT Early transcription factor 70 kDa subunit (EC 3.6.4.-) (ATP-dependent helicase VETFS) (ETF small ...
VB10_VACCT Kelch repeat protein B10
VPK2_VACCT Serine/threonine-protein kinase 2 (EC 2.7.11.1) (Vaccinia protein kinase 2)
VTF3L_VACCT Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)
VGF_VACCT Pro-vaccinia growth factor (Pro-VGF) [Cleaved into: Vaccinia growth factor (VGF) (Secreted epidermal ...
VB05_VACCT Plaque-size/host range protein (Protein B5)
VC02_VACCT Kelch repeat protein C2

22 entries

Rabbitpox virus (strain Utrecht) (RPV)

Select_allDeselect_all
RP35_RABPU DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP132_RABPU DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
SPI2_RABPU Serine proteinase inhibitor 2 (Serp-2) (Serpin-2)
SPI1_RABPU Serine proteinase inhibitor 1 (Serp-1) (Serpin-1)
PROF_RABPU Profilin
KTHY_RABPU Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
PAP1_RABPU Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)
D3_RABPU 27 kDa core protein
CAHH_RABPU Cell surface-binding protein (Carbonic anhydrase homolog)
C2_RABPU Kelch repeat protein C2
A16_RABPU Virion membrane protein A16
A18_RABPU Transcript termination protein A18 (EC 3.6.4.-)
GLRX2_RABPU Glutaredoxin-2
GLRX1_RABPU Glutaredoxin-1
H7_RABPU Late protein H7 homolog
GRFA_RABPU Growth factor (Secreted epidermal growth factor-like)
F1_RABPU Protein F1
I1_RABPU Telomere-binding protein I1
DUT_RABPU Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
VB10_RABPU Kelch repeat protein B10
VTF3L_RABPU Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)
SODL_RABPU Cu-Zn superoxide dismutase-like protein

19 entries

Camelpox virus (strain CMS)

Select_allDeselect_all
ATI_CAMPS A-type inclusion protein A25 homolog (ATI)
RP132_CAMPS DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
PROF_CAMPS Profilin
SODL_CAMPS Cu-Zn superoxide dismutase-like protein
GLRX2_CAMPS Glutaredoxin-2
KBTB1_CAMPS Kelch repeat and BTB domain-containing protein 1
KTHY_CAMPS Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
PAP1_CAMPS Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)
MCEL_CAMPS mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
CRMB_CAMPS Soluble TNF receptor II (Cytokine response-modifying protein B)
C2_CAMPS Kelch repeat protein C2
C7_CAMPS Probable host range protein 2
D3_CAMPS 27 kDa core protein
A18_CAMPS Transcript termination protein A18 (EC 3.6.4.-)
A28_CAMPS Envelope protein A28 homolog (Protein CMP145)
GRFA_CAMPS Growth factor (Secreted epidermal growth factor-like)
GLRX1_CAMPS Glutaredoxin-1
DUT_CAMPS Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
VTF3L_CAMPS Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)

19 entries

Camelpox virus (strain M-96)

Select_allDeselect_all
ATI_CAMPM A-type inclusion protein A25 homolog (ATI)
PROF_CAMPM Profilin
RP132_CAMPM DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
SODL_CAMPM Cu-Zn superoxide dismutase-like protein
GLRX1_CAMPM Glutaredoxin-1
PAP1_CAMPM Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)
MCEL_CAMPM mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
KTHY_CAMPM Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
A18_CAMPM Transcript termination protein A18 (EC 3.6.4.-)
CRMB_CAMPM Soluble TNF receptor II (Cytokine response-modifying protein B)
D3_CAMPM 27 kDa core protein
C2_CAMPM Kelch repeat protein C2
C7_CAMPM Probable host range protein 2
A28_CAMPM Envelope protein A28 homolog (Protein CMLV147)
GLRX2_CAMPM Glutaredoxin-2
GRFA_CAMPM Growth factor (Secreted epidermal growth factor-like)
F12_CAMPM Protein F12 homolog
DUT_CAMPM Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
VTF3L_CAMPM Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)

19 entries

Cowpox virus (strain GRI-90 / Grishak) (CPV)

Select_allDeselect_all
PROF_CWPXG Profilin
RP132_CWPXG DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
SODL_CWPXG Cu-Zn superoxide dismutase-like protein
GLRX2_CWPXG Glutaredoxin-2
KBTB1_CWPXG Kelch repeat and BTB domain-containing protein 1
PAP1_CWPXG Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)
P28_CWPXG E3 ubiquitin-protein ligase p28-like (EC 2.3.2.27) (Protein C7R) (RING-type E3 ubiquitin transferase ...
MCEL_CWPXG mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
KTHY_CWPXG Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
CRMB_CWPXG Soluble TNF receptor II (Cytokine response-modifying protein B)
C2_CWPXG Kelch repeat protein C2
DUT_CWPXG Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
A18_CWPXG Transcript termination protein A18 (EC 3.6.4.-)
A28_CWPXG Envelope protein A28 homolog (Protein A29)
GLRX1_CWPXG Glutaredoxin-1
HEMA_CWPXG Protein A56 (Hemagglutinin)
KBTB2_CWPXG Kelch repeat and BTB domain-containing protein 2
VD4L_CWPXG Ankyrin repeat protein D4L/I2R
VHR2_CWPXG Probable host range protein 2

18 entries

Vaccinia virus (strain L-IVP) (VACV)

Select_allDeselect_all
RIR2_VACCP Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small ...
F15_VACCP Protein F15 (Protein F2)
GLRX1_VACCP Glutaredoxin-1
F12_VACCP Protein F12 (Protein F6)
F16_VACCP Protein F16 (Protein F1)
F7_VACCP Protein F7 (Protein F11)
F5_VACCP 36 kDa major membrane protein F5
F6_VACCP Protein F6 (Protein F12)
F8_VACCP Protein F8 (Protein F10)
F9_VACCP Protein F9
I1_VACCP Telomere-binding protein I1
F13_VACCP Envelope protein F13 (37 kDa protein) (Palmitoylated EV membrane protein) (p37K)
F11_VACCP Protein F11 (Protein F7)
F14_VACCP Protein F14 (Protein F4)
DUT_VACCP Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
I2_VACCP Protein I2
VGF_VACCP Pro-vaccinia growth factor (Pro-VGF) [Cleaved into: Vaccinia growth factor (VGF) (Secreted epidermal ...
VPK2_VACCP Serine/threonine-protein kinase 2 (EC 2.7.11.1) (Vaccinia protein kinase 2)

17 entries

Cowpox virus (strain Brighton Red) (CPV)

Select_allDeselect_all
RP132_CWPXB DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
PROF_CWPXB Profilin
SPI2_CWPXB Serine proteinase inhibitor 2 (Serp-2) (Serpin-2) (Cytokine response modifier protein A) ...
SODL_CWPXB Cu-Zn superoxide dismutase-like protein
KBTB1_CWPXB Kelch repeat and BTB domain-containing protein 1
KBTB2_CWPXB Kelch repeat and BTB domain-containing protein 2
KTHY_CWPXB Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
PAP1_CWPXB Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)
MCEL_CWPXB mRNA-capping enzyme catalytic subunit (Virus termination factor large subunit) (VTF large subunit) ...
P28_CWPXB E3 ubiquitin-protein ligase p28-like (EC 2.3.2.27) (Protein CPXV023) (RING-type E3 ubiquitin ...
CP77_CWPXB Ankyrin repeat domain-containing protein CP77 (Host range protein 1)
A18_CWPXB Transcript termination protein A18 (EC 3.6.4.-)
A28_CWPXB Envelope protein A28 homolog (Protein CPXV163)
GLRX2_CWPXB Glutaredoxin-2
GLRX1_CWPXB Glutaredoxin-1
IL1BP_CWPXB Interleukin-1-binding protein (Protein B15)
SPI1_CWPXB Serine proteinase inhibitor 1 (Serp-1) (Serpin-1)

15 entries

Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)

Select_allDeselect_all
PROF_ECTVM Profilin
SEMA_ECTVM Semaphorin-like protein 139
RP132_ECTVM DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
GLRX2_ECTVM Glutaredoxin-2
KBTB1_ECTVM Kelch repeat and BTB domain-containing protein 1
PAP1_ECTVM Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)
P28_ECTVM E3 ubiquitin-protein ligase p28 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase p28-like)
KTHY_ECTVM Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)
C2_ECTVM Kelch repeat protein C2
A28_ECTVM Envelope protein A28 homolog (Protein EVM130)
A18_ECTVM Transcript termination protein A18 (EC 3.6.4.-)
GLRX1_ECTVM Glutaredoxin-1
KBTB2_ECTVM Kelch repeat and BTB domain-containing protein 2
VTF3L_ECTVM Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)
SODL_ECTVM Cu-Zn superoxide dismutase-like protein

10 entries

Monkeypox virus (strain Zaire-96-I-16) (MPX)

Select_allDeselect_all
RP132_MONPZ DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
PROF_MONPZ Profilin
SODL_MONPZ Cu-Zn superoxide dismutase-like protein
P28_MONPZ E3 ubiquitin-protein ligase p28-like (EC 2.3.2.27) (Protein D5R) (RING-type E3 ubiquitin transferase ...
KITH_MONPZ Thymidine kinase (EC 2.7.1.21)
CAHH_MONPZ Cell surface-binding protein (Carbonic anhydrase homolog)
A28_MONPZ Envelope protein A28 homolog (Protein A30)
I1_MONPZ Telomere-binding protein I1 (36 kDa late protein I1)
VHR2_MONPZ Probable host range protein 2
VTF3L_MONPZ Intermediate transcription factor 3 large subunit (VITF-3 45 kDa subunit)

3 entries

Horsepox virus (HSPV)

Select_allDeselect_all
KBTB2_HSPV Kelch repeat and BTB domain-containing protein 2
KBTB1_HSPV Kelch repeat and BTB domain-containing protein 1
PAP1_HSPV Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)

3 entries

Raccoon poxvirus (RCN)

Select_allDeselect_all
KITH_RACVI Thymidine kinase (EC 2.7.1.21)
DUSP_RACVI Probable dual specificity protein phosphatase H1 homolog (EC 3.1.3.-) (EC 3.1.3.48)
HEMA_RACVI Protein A56 (Hemagglutinin)

3 entries

Vaccinia virus (strain Dairen I) (VACV)

Select_allDeselect_all
SANS_VACCD Surface antigen S (S antigen)
E5_VACCD Protein E5
SODL_VACCD Cu-Zn superoxide dismutase-like protein

3 entries

Vaccinia virus (strain Lister) (VACV)

Select_allDeselect_all
C23L_VACCL Chemokine-binding protein (vCKBP) (35 kDa protein)
GAAP_VACCL Golgi anti-apoptotic protein (GAAP)
VB05_VACCL Plaque-size/host range protein (Protein B5)

2 entries

Cowpox virus (CPV)

Select_allDeselect_all
ATI_COWPX A-type inclusion protein A25 homolog (ATI)
CP77_COWPX Ankyrin repeat domain-containing protein CP77 (Host range protein 1)

2 entries

Vaccinia virus (strain IHD-J) (VACV)

Select_allDeselect_all
HEMA_VACCI Protein A56 (Hemagglutinin)
F13_VACCI Envelope protein F13 (37 kDa protein) (Palmitoylated EV membrane protein) (p37K)

2 entries

Vaccinia virus (strain LC16m0) (VACV)

Select_allDeselect_all
P28_VACC0 E3 ubiquitin ligase p28-like (EC 6.3.2.-)
VB05_VACC0 Plaque-size/host range protein (Protein B5)

2 entries

Vaccinia virus (strain LC16m8) (VACV)

Select_allDeselect_all
P28_VACC8 E3 ubiquitin-protein ligase p28-like (EC 2.3.2.27) (RING-type E3 ubiquitin transferase p28-like)
VB05_VACC8 Truncated plaque-size/host range protein (Protein B5)

1 entry

Camelpox virus (strain CP-1)

ATI_CAMPC A-type inclusion protein A25 homolog (ATI)

1 entry

Vaccinia virus (strain Tashkent) (VACV)

SODL_VACCU Cu-Zn superoxide dismutase-like protein

1 entry

Vaccinia virus (strain WR 65-16) (VACV)

VFUS_VACC6 14 kDa fusion protein