Herpes/interactions

Host-virus interactions of herpesvirus proteins

The table below displays a list of the most relevant interactions between herpesvirus and human proteins.

Virus Genus Viral Protein Time of expression Host protein Host protein function Reference
Herpes simplex 1 Simplexvirus Protein UL12/AN Early Protein MSH6 DNA replication/repair
Herpes simplex 1 Simplexvirus Protein UL12/AN Early Protein RAD50 DNA replication/repair
Herpes simplex 1 Simplexvirus Protein UL12/AN Early Protein MRE11 DNA replication/repair
Herpes simplex 1 Simplexvirus Protein UL12/AN Early Protein NBN DNA replication/repair
Herpes simplex 1 Simplexvirus Protein ICP47 IE Protein TAP1 Immunity/Adaptive
Herpes simplex 1 Simplexvirus Protein ICP47 IE Protein TAP2 Immunity/Adaptive
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein TRIM27 Proteasome/Ubiquitin
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein RNF8 Proteasome/Ubiquitin
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein USP7 Proteasome/Ubiquitin
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein coREST Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein IFI16 Immunity/Innate
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein PML Immunity/Innate
Herpes simplex 1 Simplexvirus Protein ICP0 IE Protein P53 Apoptosis/Survival
Herpes simplex 1 Simplexvirus Protein ICP8 Early Protein IFI16 Immunity/Innate
Herpes simplex 1 Simplexvirus Protein UL41 Late Protein EIF4A Translation
Herpes simplex 1 Simplexvirus Protein UL41 Late Protein EIF4G Translation
Herpes simplex 1 Simplexvirus Protein UL41 Late Protein EIF4H Translation
Herpes simplex 1 Simplexvirus Protein ICP34 IE Protein C1QBP Translation
Herpes simplex 1 Simplexvirus Protein ICP34 IE Protein EIF2A Translation
Herpes simplex 1 Simplexvirus Protein ICP34 IE Protein PPP1CA Translation
Herpes simplex 1 Simplexvirus Protein VP16 IE Protein HCFC1 Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein VP16 IE Protein POU2F1 Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein VP16 IE Protein GTF2B Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein VP16 IE Protein TAF9 Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein UL36 Early Protein TSG101 Vesicular Trafficking
Herpes simplex 1 Simplexvirus Protein ICP22 IE Protein CDK9 Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein ICP22 IE Protein POLR2A Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein ICP27 IE Protein ALYREF mRNA processing/Export
Herpes simplex 1 Simplexvirus Protein ICP27 IE Protein NXF1 mRNA processing/Export
Herpes simplex 1 Simplexvirus Protein ICP27 IE Protein NUP62 Nuclear pore complex
Herpes simplex 1 Simplexvirus Protein ICP27 IE Protein PABP1 mRNA processing/Export
Herpes simplex 1 Simplexvirus Protein ICP27 IE Protein SRPK1 mRNA processing/Export
Herpes simplex 1 Simplexvirus Protein US11 Late Protein PKR Immunity/Innate
Herpes simplex 1 Simplexvirus Protein US11 Late Protein DDX58 Immunity/Innate
Herpes simplex 1 Simplexvirus Protein US11 Late Protein IFIH1 Immunity/Innate
Herpes simplex 1 Simplexvirus Protein UL25 Late Protein C9orf69 Cell cycle
Herpes simplex 1 Simplexvirus Protein UL25 Late Protein NUP214 Nuclear pore complex
Herpes simplex 1 Simplexvirus Protein US2 Early Protein KRT18 -
Herpes simplex 1 Simplexvirus Protein GB Late Protein PILRA Receptor
Herpes simplex 1 Simplexvirus Protein GB Late Protein PDGRFA Receptor
Herpes simplex 1 Simplexvirus Protein GC Late Protein C3B Receptor
Herpes simplex 1 Simplexvirus Protein GD Late Protein TNFRSF14 Receptor
Herpes simplex 1 Simplexvirus Protein GD Late Protein Nectin-1 Receptor
Herpes simplex 1 Simplexvirus Protein GD Late Protein Nectin-2 Receptor
Herpes simplex 1 Simplexvirus Protein GE Late Protein IGHG1 Immunity/Adaptive
Herpes simplex 1 Simplexvirus Protein GH Late Protein ITGA5/B3 Receptor
Herpes simplex 1 Simplexvirus Protein ICP4 IE Protein TBP Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein ICP4 IE Protein TAF1 Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein UL9 Early Protein POLA1 DNA replication/repair
Herpes simplex 1 Simplexvirus Protein UL42 Late Protein RELA Apoptosis/Survival
Herpes simplex 1 Simplexvirus Protein UL42 Late Protein NFKB1 Immunity/Innate
Herpes simplex 1 Simplexvirus Protein UL46 Early Protein LCK Immunity/Adaptive
Herpes simplex 1 Simplexvirus Protein UL46 Early Protein SHC1 Apoptosis/Survival
Herpes simplex 1 Simplexvirus Protein UL46 Early Protein GRB2 Apoptosis/Survival
Herpes simplex 1 Simplexvirus Protein VP22 Early Protein SET Chromatin/Transcription
Herpes simplex 1 Simplexvirus Protein UL47 Early Protein PABP1 mRNA processing/Export
Herpes simplex 1 Simplexvirus Protein UL37 Late Protein DST -
Herpes simplex 1 Simplexvirus Protein UL37 Late Protein TRAF6 Proteasome/Ubiquitin
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein P53 Apoptosis/Survival
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein STAT2 Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein DAXX Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein PML Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein SP100 Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein E2F1 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein IE1 IE Protein RB1 Cell cycle
Human cytomegalovirus Cytomegalovirus Protein IE2 IE Protein HDAC2 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein IE2 IE Protein TBP Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein IE2 IE Protein TFIIB Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein IE2 IE Protein CHAF1A Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein GB Late Protein ITGB1 Receptor
Human cytomegalovirus Cytomegalovirus Protein GB Late Protein EGFR Receptor
Human cytomegalovirus Cytomegalovirus Protein GM Late Protein FIP4 Vesicular Trafficking
Human cytomegalovirus Cytomegalovirus Protein UL69 IE Protein SPT6 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL69 IE Protein UAP56 mRNA processing/export
Human cytomegalovirus Cytomegalovirus Protein UL69 IE Protein DDX39A mRNA processing/export
Human cytomegalovirus Cytomegalovirus Protein UL69 IE Protein CYCT1 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL69 IE Protein EIF4A Translation
Human cytomegalovirus Cytomegalovirus Protein UL69 IE Protein PAPBC1 mRNA processing/export
Human cytomegalovirus Cytomegalovirus Protein IRS1 IE Protein PKR Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein TRS1 IE Protein PKR Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein TRS1 IE Protein BECN1 Autophagy
Human cytomegalovirus Cytomegalovirus Protein UL11 Early Protein PTPRC Immunity/Adaptive
Human cytomegalovirus Cytomegalovirus Protein UL21A Early Protein CYCA2 Cell cycle
Human cytomegalovirus Cytomegalovirus Protein UL27 Early Protein KAT5 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL27 Early Protein PSME3 Protesasome/Ubiquitin
Human cytomegalovirus Cytomegalovirus Protein UL27 ? Protein EP400 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL28/29 Early Protein HDAC1 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL28/29 Early Protein MTA2 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL33 ? Protein CCR5 Receptor
Human cytomegalovirus Cytomegalovirus Protein UL33 ? Protein CXCR4 Receptor
Human cytomegalovirus Cytomegalovirus Protein UL82 ? Protein DAXX Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL70 ? Protein SNAPIN Vesicule trafficking
Human cytomegalovirus Cytomegalovirus Protein US2 Early Protein TRAM1 Vesicule trafficking
Human cytomegalovirus Cytomegalovirus Protein US2 Early Protein CD1D Immunity/Adaptive
Human cytomegalovirus Cytomegalovirus Protein US3 Early Protein TAPASIN Imunity/Adaptive
Human cytomegalovirus Cytomegalovirus Protein US6 Early Protein TAP1 Imunity/Adaptive
Human cytomegalovirus Cytomegalovirus Protein US11 Early Protein TRAM1 Vesicule trafficking
Human cytomegalovirus Cytomegalovirus Protein UL32 Late Protein BIDC1 Vesicule trafficking
Human cytomegalovirus Cytomegalovirus Protein UL36 IE Protein CASP8 Apoptosis/Survival
Human cytomegalovirus Cytomegalovirus Protein UL37 IE Protein BAX Apoptosis/Survival
Human cytomegalovirus Cytomegalovirus Protein UL37 IE Protein VIPERIN Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein UL38 IE Protein TSC2 Apoptosis/Survival
Human cytomegalovirus Cytomegalovirus Protein UL44 ? Protein SMARCB1 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL44 ? Protein NCL Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL76 ? Protein PSMD4 Ubiquitin/Proteasome
Human cytomegalovirus Cytomegalovirus Protein UL78 ? Protein CCR5 Receptor
Human cytomegalovirus Cytomegalovirus Protein UL78 ? Protein CXCR4 Receptor
Human cytomegalovirus Cytomegalovirus Protein UL111 ? Protein IL10RA Immunity/Innate
Human cytomegalovirus Cytomegalovirus Protein UL114 ? Protein SMARCB1 Chromatin/Transcription
Human cytomegalovirus Cytomegalovirus Protein UL119/UL118 ? Protein IG G1 Immunity/Adaptive
Human cytomegalovirus Cytomegalovirus Protein UL136 ? Protein ATP1B1 -
Human cytomegalovirus Cytomegalovirus Protein UL141 ? Protein PVR -
Human cytomegalovirus Cytomegalovirus Protein UL141 ? Protein TNFRSF10A Receptor
Human cytomegalovirus Cytomegalovirus Protein UL141 ? Protein TNFRSF10B Receptor
Human cytomegalovirus Cytomegalovirus Protein UL142 ? Protein SNAPIN Vesicule trafficking
Human cytomegalovirus Cytomegalovirus Protein UL144 ? Protein TRIM23 Ubiquitin proteasome
Human cytomegalovirus Cytomegalovirus Protein UL146 ? Protein CXCR1 Receptor
Human cytomegalovirus Cytomegalovirus Protein UL146 ? Protein CXCR2 Receptor
Epstein-Barr virus Lymphocryptovirus Protein EBNA1 Latency Protein USP7 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein EBNA1 Latency Protein EBP2 mRNAprocessing/Export
Epstein-Barr virus Lymphocryptovirus Protein EBNA1 Latency Protein NCL Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA1 Latency Protein CDC6 DNA replication/repair
Epstein-Barr virus Lymphocryptovirus Protein EBNA1 Latency Protein BRD4 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA2 Latency Protein SMARCB1 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA2 Latency Protein RBPJ Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA2 Latency Protein TFIIH Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA2 Latency Protein ZMYND11 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA2 Latency Protein TAF11 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA2 Latency Protein TFIIB Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3 Latency Protein AIP Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3 Latency Protein CTBP1 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3 Latency Protein UCKL1 -
Epstein-Barr virus Lymphocryptovirus Protein EBNA3 Latency Protein RBPJ Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3B Latency Protein RBPJ Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3C Latency Protein RBPJ Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3C Latency Protein H2AX Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3C Latency Protein MYC Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3C Latency Protein CTBP1 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3C Latency Protein P73 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein EBNA3C Latency Protein HDAC1 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein BALF5 Early Protein PIN1 -
Epstein-Barr virus Lymphocryptovirus Protein BNRF1 ? Protein DAXX Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein LMP1 Latency Protein ZMYND11 Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein LMP1 Latency Protein TRAFS 1,2,3 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein LMP1 Latency Protein UBE2I Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein LMP1 Latency Protein IRF7 Immunity/Innate
Epstein-Barr virus Lymphocryptovirus Protein LMP1 Latency Protein RABAC1 Vesicule trafficking
Epstein-Barr virus Lymphocryptovirus Protein LMP2 Latency Protein SYK Immunity/Adaptive
Epstein-Barr virus Lymphocryptovirus Protein LMP2 Latency Protein LYN Immunity/Adaptive
Epstein-Barr virus Lymphocryptovirus Protein LMP2 Latency Protein ITCH Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein LMP2 Latency Protein WWP2 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein LMP2 Latency Protein NEDD4L Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BZLF1 IE Protein RACK1 Apoptosis/Survival
Epstein-Barr virus Lymphocryptovirus Protein BZLF1 IE Protein CRTC2 Apoptosis/Survival
Epstein-Barr virus Lymphocryptovirus Protein BZLF1 IE Protein RELA Apoptosis/Survival
Epstein-Barr virus Lymphocryptovirus Protein BZLF1 IE Protein UBN1 -
Epstein-Barr virus Lymphocryptovirus Protein BGLF4 ? Protein NUP62 Nucleoporin
Epstein-Barr virus Lymphocryptovirus Protein BGLF4 ? Protein NUP153 Nucleoporin
Epstein-Barr virus Lymphocryptovirus Protein BGLF4 ? Protein SUMO1 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BGLF4 ? Protein SUMO2 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BMRF2 ? Protein ITGB1 Receptor
Epstein-Barr virus Lymphocryptovirus Protein BNLF2a ? Protein TAP1 Immunity/Adaptive
Epstein-Barr virus Lymphocryptovirus Protein BNLF2a ? Protein TAP2 Immunity/Adaptive
Epstein-Barr virus Lymphocryptovirus Protein BPLF1 ? Protein CUL1 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BPLF1 ? Protein CUL4A Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BPLF1 ? Protein RAD18 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BPLF1 ? Protein PCNA DNA replication/repair
Epstein-Barr virus Lymphocryptovirus Protein BPLF1 ? Protein TRAF6 Ubiquitin/Proteasome
Epstein-Barr virus Lymphocryptovirus Protein BLLF1 Late Protein CR2 Receptor
Epstein-Barr virus Lymphocryptovirus Protein BZLF2 Late Protein HLA-DRA Receptor
Epstein-Barr virus Lymphocryptovirus Protein BZLF2 Late Protein HLA-DRB1 Receptor
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein NXF1 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein XPO1 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein OTT1 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein OTT3 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein SHARP Chromatin/Transcription
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein SRSF1 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein SRSF3 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BMLF1 ? Protein SRSF7 mRNA processing/export
Epstein-Barr virus Lymphocryptovirus Protein BCRF1 ? Protein IL10RA Receptor
Kaposi sarcoma virus Rhadinovirus Protein vFLIP/K13 ? Protein TRAF2 Ubiquitin/Proteasome
Kaposi sarcoma virus Rhadinovirus Protein vFLIP/K13 ? Protein MAP3K14 Apoptosis/Survival
Kaposi sarcoma virus Rhadinovirus Protein vFLIP/K13 ? Protein IKBKB Apoptosis/Survival
Kaposi sarcoma virus Rhadinovirus Protein vFLIP/K13 ? Protein RIPK1 Apoptosis/Survival
Kaposi sarcoma virus Rhadinovirus Protein vFLIP/K13 ? Protein IKBKG Apoptosis/Survival
Kaposi sarcoma virus Rhadinovirus Protein vIRF1/K9 ? Protein IRF3 Immunity/Innate
Kaposi sarcoma virus Rhadinovirus Protein vIRF1/K9 ? Protein IRF7 Immunity/Innate
Kaposi sarcoma virus Rhadinovirus Protein vIRF1/K9 ? Protein CREBBP Chromatin/Transcription
Kaposi sarcoma virus Rhadinovirus Protein vIRF2/K11 ? Protein PKR Immunity/Innate
Kaposi sarcoma virus Rhadinovirus Protein vIRF3/K10 ? Protein SKP2 Ubiquitin/Proteasome
Kaposi sarcoma virus Rhadinovirus Protein vIRF4 ? Protein MDM2 Ubiquitin/Proteasome
Kaposi sarcoma virus Rhadinovirus Protein K7 ? Protein CAMLG -
Kaposi sarcoma virus Rhadinovirus Protein K8 ? Protein HDAC1 Chromatin/Transcription
Kaposi sarcoma virus Rhadinovirus Protein K8 ? Protein HDAC2 Chromatin/Transcription
Kaposi sarcoma virus Rhadinovirus Protein K8 ? Protein SMARCB1 Chromatin/Transcription
Kaposi sarcoma virus Rhadinovirus Protein K8 ? Protein UBE2I Ubiquitin/Proteasome
Kaposi sarcoma virus Rhadinovirus Protein K14 ? Protein CD200R1 Receptor
Kaposi sarcoma virus Rhadinovirus Protein ORF50 ? Protein POU2F1 Chromatin/Transcription
Kaposi sarcoma virus Rhadinovirus Protein GB ? Protein ITGB3 Receptor
Kaposi sarcoma virus Rhadinovirus Protein ORF57 ? Protein ALYREF mRNA processing/Export
Kaposi sarcoma virus Rhadinovirus Protein ORF57 ? Protein NXF1 mRNA processing/Export
Kaposi sarcoma virus Rhadinovirus Protein ORF57 ? Protein OTT1 mRNA processing/Export
Kaposi sarcoma virus Rhadinovirus Protein ORF57 ? Protein OTT3 mRNA processing/Export
Kaposi sarcoma virus Rhadinovirus Protein K1 ? Protein HSP90B -
Kaposi sarcoma virus Rhadinovirus Protein K1 ? Protein HSP40 -
Kaposi sarcoma virus Rhadinovirus Protein K1 ? Protein SYK Immunity/Adaptive
Kaposi sarcoma virus Rhadinovirus Protein K2 ? Protein IL6ST Immunity/Adaptive
Kaposi sarcoma virus Rhadinovirus Protein ORF45 ? Protein IRF7 Immunity/Adaptive
Kaposi sarcoma virus Rhadinovirus Protein K15 ? Protein LYN Immunity/Adaptive
Kaposi sarcoma virus Rhadinovirus Protein K15 ? Protein ITSN2 -
Kaposi sarcoma virus Rhadinovirus Protein GH Late Protein EPHA2 Receptor
Kaposi sarcoma virus Rhadinovirus Protein LANA Latent Protein TRIM28 Receptor
Kaposi sarcoma virus Rhadinovirus Protein LANA Latent Protein H2A Receptor
Kaposi sarcoma virus Rhadinovirus Protein LANA Latent Protein H2B Receptor